Genes News and Research

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Importance of localizing BRCA gene mutations for ovarian cancer treatment

Mutations in the BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 persons, respectively, elevate the risk of various malignancies such as ovarian, breast, pancreatic, and prostate cancer considerably.

30 Nov 2022

Study unravels a novel function of the gene scissors

Many years earlier, the CRISPR/Cas9 gene scissors have been making a sensation in science and medicine. This new tool of molecular biology consists of its origins in an ancient bacterial immune system.

28 Nov 2022

Gaining better insights into the origins of jaws by DNA sequence

At Uppsala University, a DNA sequence found in jawed vertebrates has been discovered and characterized by scientists. This includes sharks and humans, but it is absent in jawless vertebrates, like lampreys.

28 Nov 2022

AI creates artificial DNA to control cell protein production

Researchers at Chalmers University of Technology in Sweden have developed synthetic DNA that uses artificial intelligence to control the production of proteins in cells.

25 Nov 2022

Newly developed tool helps snip out faulty genes in a safe manner

Scientists from the Massachusetts Institute of Technology (MIT) have come up with a new tool that has the potential to detach faulty genes and exchange them with new ones in a highly safe and effective way.

From Massachusetts Institute of Technology (MIT) 25 Nov 2022

Breakthrough on the way to new therapeutic strategies

As far as the field of cancer research is concerned, hollow spheres composed of MYC proteins sets the stage. Researchers from Würzburg have found them out and have reported this discovery in the Nature journal.

25 Nov 2022

Fastest-evolved regions of the human genome diverged rapidly after split from chimpanzee ancestor

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

New computational approach enhances the performance of bioinformatics tools

UVA Health researchers have created an innovative tool to assist scientists in distinguishing signals from noise as they investigate the genetic underpinnings of cancer and other disorders.

24 Nov 2022

New effort to generate high quality reference genomes for 1,000 known species of euglenoids

The Euglena International Network (EIN) (https://euglenanetwork.org/), founded in 2020, is a global consortium of hundreds of scientists around the world with the collective goal of supporting euglenoid science through collaborative and integrative omics between academics and industry.

23 Nov 2022

Highlighting the potential of new techniques to study mental disorders

Researchers investigating the fundamental brain mechanics of autism spectrum disorder have discovered that a gene mutation known to be connected with the illness causes considerably more overstimulation of brain cells than in neuronal cells without the mutation.

23 Nov 2022

The influence of genes and small molecules on personal disease risk

Each individual has a unique chemical fingerprint. Small molecules in the blood, like fats or sugars, have a significant impact on how the human body responds to stress, which diseases people are predisposed to, and how serious an illness will be.

23 Nov 2022

Molecular motion of “undruggable” proteins reveals drug-binding sites

“Undruggable” proteins, whose structures and roles in disease are known but who appear unable to be targeted by drugs that will bind to them, present some of the hardest problems in disease treatment.

23 Nov 2022

3D “mini eyes” provide insight into genetically induced blindness

The development of “mini eyes” by researchers at the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) has made it possible to study and comprehend the onset of blindness in the rare genetic disease known as Usher syndrome more.

From University College London 22 Nov 2022

Genetics and extensive schooling likely cause nearsightedness in children

Researchers have discovered five genetic variations that, the longer a person attends school, increase their risk of developing nearsightedness. These results were published on November 17th, 2022 in the open-access journal PLOS Genetics by a team at Cardiff University in the United Kingdom, led by Jeremy Guggenheim.

21 Nov 2022

Adaptation to climate change in plants aided by epigenetic memories

Animals are able to quickly adapt to changing environmental conditions and survive. There is growing evidence that plants can, too.

21 Nov 2022

Mitochondria play a crucial role in the regulation of the NF-κB signaling pathway

Mitochondria are highly regarded as the cell's powerhouse. However, these cellular organelles are essential for more than only energy production: Professor Konstanze Winklhofer and her colleagues at Ruhr University Bochum’s Faculty of Medicine have found that mitochondria play an essential role in signal transduction in innate immune pathways.

21 Nov 2022

Revealing the functional significance of DDX41 in great detail

The DDX41 gene encodes the nuclear enzyme DEAD-box-type RNA helicase. Hematopoietic malignancies are caused by DDX41 mutations. However, the mechanism behind the development of this malignancy remains unknown.

21 Nov 2022

Scientists discover how plant roots adapt their shape to maximize water uptake

Researchers have discovered how plant roots adapt their shape to maximise their uptake of water, pausing branching when they lose contact with water and only resuming once they reconnect with moisture, ensuring they can survive even in the driest conditions.

19 Nov 2022

Waste disposal mechanism of mitochondria to remove mtDNA mutations

University of Cologne researchers have uncovered the mechanism by which cells can get rid of mutated mitochondrial DNA (mtDNA)—the heart of each of our cells, the mitochondria.

17 Nov 2022

The genetic mechanisms that induce protein decline in modern maize

The wild ancestor of maize, teosinte, contains three times as much seed protein as the majority of cultivars of maize today. The mechanisms causing the declining seed protein content in maize hybrids and inbred lines were identified by researchers at the Chinese Academy of Sciences Headquarters.

17 Nov 2022