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Black death and the development of immune genes

The Black Death, which wiped off up to 50% of the European population in less than five years, was the single-worst mortality catastrophe in recorded history.

21 Oct 2022

Meiotic drive systems can be maintained for long evolutionary timespans

Meiotic drivers, which are a sort of selfish gene, are, in fact, selfish. They are found in nearly all species’ genomes, including humans, and unfairly convey their genetic information to more than half of their offspring, resulting in infertility and impaired organism health.

21 Oct 2022

All normal human tissues express remnants of widespread retrovirus

Ancient viral remnants in the human genome are active in both healthy and diseased tissues, restricting their applicability as disease indicators, according to a study published on October 18th, 2022, in the open access journal PLOS Biology by Aidan Burn at Tufts University in Boston, USA and colleagues.

20 Oct 2022

Saving ocean habitats with newer genomic technologies

In an essay published on October 17th, 2022 in the open-access journal PLOS Biology, Madeleine van Oppen of the Australian Institute of Marine Science and the University of Melbourne and Melinda Coleman of the New South Wales Department of Primary Industries argue that genetic and genomic technologies have tremendous potential for protecting marine life but are currently underutilized.

20 Oct 2022

Novel method for comparing single-cell trajectories with tree alignment

The genes that are activated in a single cell can now be determined thanks to advances in high-throughput biological studies. However, interpreting the resulting complex datasets might be difficult.

From Osaka University 20 Oct 2022

Large 'omics' dataset reveals a year in the biological life of Arctic Ocean

A major new project will help benchmark biodiversity change in the Arctic Ocean and guide conservation efforts by identifying unique species and assessing their extinction risk.

18 Oct 2022

Innovative method opens myriad new avenues for understanding the biology behind COVID-19

A highly innovative method using the latest technology has generated a comprehensive list of SARS-CoV-2 viral and human proteins that interact with each other, with one such interaction showing the virus directly influencing proteins that regulate the human immune system.

18 Oct 2022

An accurate overview of gene activity could provide targeted therapies

Normal gene activity in the afflicted cells is changed during pathological events. Therefore, obtaining a precise picture of gene activity could hold the key to the creation of new, targeted therapies.

18 Oct 2022

Role of hormones and their receptors in the plant stress response

Crops are frequently subjected to unfavorable growing conditions. Disease, severe temperatures, and saline soils, for example, cause plants to utilize energy to adapt to stress rather than for development.

18 Oct 2022

Prolonged longevity in mice with gene clusters

Numerous candidate genes that affect longevity have recently been found, according to research from the Interventions Testing Program, which is supported by the National Institute on Aging (NIA).

14 Oct 2022

A more efficient way to deliver gene therapies to the CNS

For gene therapy, the blood-brain barrier (BBB) poses a formidable obstacle. The BBB, which is made up of cells that are closely packed together, prevents poisons and pathogens from accessing brain tissue while also blocking potential treatments for diseases that impact the CNS.

12 Oct 2022

New technique identifies tumor-associated microbes

Researchers from Rutgers Cancer Institute of New Jersey and RWJBarnabas Health investigated the microbiome of pancreatic tumors and discovered certain microbes linked to inflammation and poor survival.

From Rutgers University 12 Oct 2022

Discovery and characterization of a new antifungal compound

Antimicrobial resistance has prompted scientists to search for novel compounds everywhere. A multinational group of European scientists reports the discovery of solanimycin, a novel antifungal antibiotic.

12 Oct 2022

Building designer plant cuticles with important protective functions

Scientists are working to bioengineer a common defense mechanism that most plants develop naturally to protect against drought, insects and other environmental stresses.

11 Oct 2022

Adults with congenital blindness experience striking recoveries of night vision after gene therapy

Adults with a genetic form of childhood-onset blindness experienced striking recoveries of night vision within days of receiving an experimental gene therapy, according to researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

11 Oct 2022

The science behind gene activation in plants

Researchers explain how a particular variety of GFP can be utilized to allow people to visually observe protein synthesis in this study.

10 Oct 2022

Distinct roles of aging and genetics on expression phenotypes

Research conducted by the University of California, Berkeley, found that individual distinctions in human DNA matter less as people age and become more susceptible to aging disorders like diabetes and cancer.

10 Oct 2022

Genomic research helps in tackling the fatal complications of fungal infections

An important genetic discovery made by a research team led by a University of Massachusetts Amherst scientist sheds new light on the application of the drug caspofungin to treat the deadly fungal infection Aspergillus fumigatus, which claims the lives of about 100,000 severely immunocompromised individuals every year.

7 Oct 2022

A remarkable finding reorients attempts to cure liver disease

A long-running debate in gastroenterology has been settled by WEHI researchers who have shown that prevalent liver diseases are not caused by inflammatory cell death as previously believed.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Oct 2022

Multi-institutional project aims to deepen the understanding of a versatile bioenergy crop

Principal Investigator, Andrea Eveland, Ph.D., associate member at the Donald Danforth Plant Science Center, will lead a multi-institutional project to deepen the understanding of sorghum, a versatile bioenergy crop, and its response to drought.

6 Oct 2022