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Lack of functional GAS2 gene causes severe hearing impairment in mice

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

10 May 2021

Genomic Analysis for the Conservation of Koalas

In this interview, AZoLifeSciences speaks to Professor Parwinder Kaur about her latest research that uses genomic analysis for the conservation of koalas.

From The University of Western Australia 10 May 2021

Highly efficient method to identify the genetic “switches” that control gene expression

Scientists have created a high-throughput method to help explain and regulate gene expression for the treatment of diseases like beta-thalassemia and sickle cell disease.

7 May 2021

Study defines genetic positions associated with the progression of Parkinson’s disease

The progression of Parkinson’s disease (PD) is an important factor in patients’ well-being and clinical trials.

7 May 2021

Study reveals that bacteria DNA signals can be read either forward or backward

Bacteria’s DNA signals have symmetry that allows them to be read either backward or forward, challenging the current understanding of gene transcription.

7 May 2021

Study suggests that bubonic plague had long-term impact on human immune genes

Scientists examining the remains of 36 bubonic plague victims from a 16th century mass grave in Germany have found the first evidence that evolutionary adaptive processes, driven by the disease, may have conferred immunity on later generations of people from the region.

7 May 2021

New open-source image library illustrates content on genome-editing and their use in plants

Are you looking for clear, accurate images to bring your content on genome-editing and genetic modification to life? The John Innes Center has launched an open-source image library for journalists, writers and picture editors seeking to illustrate content on these important technologies and their use in plants.

7 May 2021

Researchers map unique genetic profile of osteocytes for the first time

Researchers have mapped the specific genetic profile of the skeleton’s “master regulator” cells, called osteocytes, for the first time.

7 May 2021

Research uncovers how antibiotics target bacterial RNA Polymerase to inhibit gene transcription

The emergence and spread of new forms of resistance remains a concern that urgently demand new antibiotics. Transcription is a vital process in bacterial cell, where genetic information in DNA is transcribed to RNA for the translation of proteins that perform cellular function.

6 May 2021

Researchers sequence genome of raccoon dogs that are reservoir hosts for coronaviruses

For the first time, a research team has sequenced the genome of a raccoon dog. Genetic data now supports the animal’s ability to spread SARS-CoV-2.

6 May 2021

New technology efficiently detects gene mutation in blood with low error rate

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

5 May 2021

Study reveals genetic mutation associated with exfoliation syndrome

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma.

5 May 2021

Mutant corn gene found to increase the amount of sugars in the seeds and leaves

An abnormal accumulation of carbohydrates—starches and sugars—in the kernels and leaves of a mutant line of corn can be traced back to a single misregulated gene, and this finding provides insights into how the plant responds to stress.

From Penn State University 5 May 2021

New atlas may support present and future conservation efforts to protect coral reefs

A team of researchers has created the world’s first atlas of all the different types of cells in a reef-building stony coral that inhabits the Indo-Pacific oceans.

5 May 2021

Study reveals relationship between form and function in the genetic material of dinoflagellates

A new study unfolds a longstanding puzzle about the connection between the function and form in the genetic material of a complex group of algae.

5 May 2021

New nanopore sequencing tool can identify the existence of nucleobases

Nanopore technology has the potential to enable the development of portable, low-cost, small devices capable of real-time DNA sequencing.

4 May 2021

New genetic database maps how immune disorders evolve

A first-of-its-kind genetic database for autoinflammatory and autoimmune disorders has been created by Japanese researchers.

4 May 2021

Researchers study the unique genomic organization of coral symbionts

According to recent findings, the genome of single-celled plankton, called dinoflagellates, is arranged in an extremely unusual and strange manner. The study results set the foundations for further research into these vital aquatic species and significantly broaden the understanding of what a eukaryotic genome can look like.

3 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

New gene therapy could help treat Duchenne muscular dystrophy

Researchers from UT Southwestern used a new kind of gene therapy to successfully treat mice with Duchenne muscular dystrophy (DMD), distinctively employing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein missing in several DMD patients.

3 May 2021