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T cell-driven changes in the gut may affect brain function associated with depression

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.

21 Mar 2023

Genome editing proven effective to restore the vision of mice with genetic diseases

Chinese researchers have turned out to be successful in restoring the vision of mice with retinitis pigmentosa, which is considered to be one of the significant causes of blindness in humans.

20 Mar 2023

Study presents top 100 research questions facing plant science

Without plants, we'd have no air to breathe or food to eat, yet plant science lingers in the shadowy wings while other fields take center stage.

20 Mar 2023

Genomic study helps to better understand the origins, history of Tibetan and Sherpa ethnic groups

The Tibetan Plateau, the highest and largest plateau above sea level, is one of the harshest environments settled by humans.

20 Mar 2023

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

University of Utah Health scientists have corrected abnormal heart rhythms in mice by restoring healthy levels of a protein that heart cells need to establish connections with one another.

20 Mar 2023

Study may help identify new sex-specific treatments for depression

Depression is widely reported to be more common in women than in men, with women twice as likely to receive a diagnosis than men.

20 Mar 2023

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

20 Mar 2023

Previously unknown genetic causes of three rare conditions discovered

Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.

20 Mar 2023

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.

17 Mar 2023

Novel genetics tool for mining impact assessment and biomonitoring of endangered chimpanzees

The western chimpanzees of Guinea are threatened by mining activities. Using a novel genetic approach, UZH researchers and an international team have collected information on population size and community structure of the endangered species.

17 Mar 2023

Genomic analysis shows Ashaninka people are not as homogeneous as previously reported

The Ashaninka are the most numerous Indigenous people living in the rainforests of Peru and Brazil where they inhabit a crucial area between the Andes and sources of the Amazon River. And yet, despite the size of the population and their importance in the past and present, their genetic history has remained understudied.

17 Mar 2023

Researchers discover previously unknown genetic causes of three rare conditions

17 Mar 2023

The impact of genome doubling on the development of cancer

Since a single cell has 2–3 m of DNA, the only method to store it is in tight coils. The answer is chromatin, a DNA-protein complex that is wrapped around histone proteins.

17 Mar 2023

Influence of molecular component of caffeine on gut health

Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).

16 Mar 2023

Novel web-based tool deoptimizes genetic sequences based on different codon usage

A new software tool developed by Texas Biomedical Research Institute and collaborators can help scientists and vaccine developers quickly edit genetic blueprints of pathogens to make them less harmful.

16 Mar 2023

High blood caffeine levels lower body fat and the long-term risks of type 2 diabetes, study finds

A high blood caffeine level might curb the amount of body fat a person carries and their risk of type 2 diabetes, suggests research published in the open access journal BMJ Medicine.

16 Mar 2023

Novel newborn screening test for HCU works by measuring homocysteine levels

Scientists have developed a test that could greatly improve quality of life for infants with homocystinuria (HCU)-;a congenital disease that, if not treated early, causes serious complications. Research demonstrating the efficacy of this test was published today in AACC's Clinical Chemistry journal.

16 Mar 2023

Study evaluates the risk posed by the fungus Bd to amphibians across the continent of Africa

Mass fungus infections that drive populations worldwide to near-collapse don't just occur in science fiction. Chytridiomycosis, the worst vertebrate disease in recorded history, has already wiped out hundreds of species of amphibians around the world. Due to a large part to this fungal disease, 41% of amphibians are currently threatened with extinction. Only species living in Africa seemed to have been relatively spared from the scourge of chytridiomycosis – at least so far.

15 Mar 2023

Gene that regulates cadmium distribution between leaf and grain in rice

Due to its accumulation in crops, specifically rice, cadmium (Cd), a hazardous heavy metal contaminant of cultivated land, poses a threat to human health. Thus, it is vital to develop methods to prevent Cd from accumulating in rice grains.

14 Mar 2023

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Synthetic biologists at Rice University are embarking on a three-year project to create "genetically encoded antibiotics," strands of RNA that bacteria will readily copy and share that will selectively kill only disease-causing, pathogenic bacteria.

14 Mar 2023

Genetic News and Research

T cell-driven changes in the gut may affect brain function associated with depression

Genome editing proven effective to restore the vision of mice with genetic diseases

Study presents top 100 research questions facing plant science

Genomic study helps to better understand the origins, history of Tibetan and Sherpa ethnic groups

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

Study may help identify new sex-specific treatments for depression

Cancer cells use new DNA repair mechanism to recover from next-generation cancer radiation therapy

Previously unknown genetic causes of three rare conditions discovered

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Novel genetics tool for mining impact assessment and biomonitoring of endangered chimpanzees

Genomic analysis shows Ashaninka people are not as homogeneous as previously reported

Researchers discover previously unknown genetic causes of three rare conditions

The impact of genome doubling on the development of cancer

Influence of molecular component of caffeine on gut health

Novel web-based tool deoptimizes genetic sequences based on different codon usage

High blood caffeine levels lower body fat and the long-term risks of type 2 diabetes, study finds

Novel newborn screening test for HCU works by measuring homocysteine levels

Study evaluates the risk posed by the fungus Bd to amphibians across the continent of Africa

Gene that regulates cadmium distribution between leaf and grain in rice

Rice biologists embark on a three-year project to create genetically encoded antibiotics

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