Genetic News and Research

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Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

From Harvard Medical School 15 Apr 2022

Immune cell migration contributes to inefficient antitumor immunity, study finds

Mutations in the APC gene cause the production of intestinal polyps in persons suffering from familial adenomatous polyposis, a genetic disease that predisposes them to colon cancer.

From Institut Pasteur 15 Apr 2022

Bioprinting bone along with two growth factor encoding genes improves bone repair

Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing.

From Penn State University 13 Apr 2022

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

VectorBuilder Inc. has announced the construction of a new R&D and manufacturing center in Guangzhou, China.

From VectorBuilder 12 Apr 2022

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

11 Apr 2022

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

A single cell’s genome or transcriptome can reveal considerably more data about its place in biological systems than sequencing a full batch of cells, just as interviewing a single person about their health will provide specialized, personalized information hard to obtain from a big poll.

11 Apr 2022

Single-molecule analysis to study how tetraploid cells replicate DNA from diploid cells

Human cells have two sets of chromosomes (diploid). It is possible, however, that cells have a tetraploid (quadruple) set.

11 Apr 2022

Researchers identify specific genes that cause schizophrenia

A substantial number of individual genes that potentially play essential roles in schizophrenia have been uncovered in the largest-ever genomic analysis of the psychiatric condition.

11 Apr 2022

Intracellular microbiota promote cell survival during tumor progression

Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report April 7th in the journal Cell.

8 Apr 2022

Researchers identify a large number of specific genes associated with schizophrenia

What is the role of genetics in schizophrenia? To address this question, an international group of researchers led by Charité – Universitätsmedizin Berlin and Cardiff University developed and conducted the largest-ever genetic study on schizophrenia.

8 Apr 2022

Mice study explains why humans expressing CHT gene variant exhibit attentional vulnerabilities

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD).

8 Apr 2022

Edinburgh scientists solve century-old evolutionary puzzle about malaria parasites

Scientists have solved a 100-year-old mystery about the evolutionary links between malaria parasites that infect humans and chimpanzees.

7 Apr 2022

Scientists identify factors that regulate the development of brain cells in a specific order

Researchers have identified the complete series of 10 factors that regulate the development of brain cell types in the visual system of fruit flies-; including in what order these neurons develop.

From New York University (NYU) 7 Apr 2022

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

A vaccine for hepatitis C has eluded scientists for more than 30 years, for several reasons. For one, the virus that causes the disease comes in many genetic forms, complicating the creation of a widely effective vaccine.

7 Apr 2022

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

7 Apr 2022

Researchers discover how an “accordion effect” is vital for switching off genes

In a study that changes the fundamentals of what researchers know about gene silencing, WEHI researchers demonstrated how an “accordion effect” is key to switching off genes.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Apr 2022

Transposons are a potential antibiotic resistance, a study reveals

According to biomedical engineers at Duke University, the physical mechanism that enables high doses of antibiotics to encourage the transmission of antibiotic resistance across bacteria is now identified.

7 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

Novel method to obtain genomic data shows potential success

Researchers at the University of Otago have developed a novel technique for acquiring ancient genomic data without causing damage to the source material, opening up new possibilities for museum and archaeological collections around the world.

7 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

Genetic News and Research

Spatial maps offer insights into the battle between melanoma cells and immune cells

Immune cell migration contributes to inefficient antitumor immunity, study finds

Bioprinting bone along with two growth factor encoding genes improves bone repair

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Researchers develop a universal AI algorithm for deep clean-up of single cell genomic data

Single-molecule analysis to study how tetraploid cells replicate DNA from diploid cells

Researchers identify specific genes that cause schizophrenia

Intracellular microbiota promote cell survival during tumor progression

Researchers identify a large number of specific genes associated with schizophrenia

Mice study explains why humans expressing CHT gene variant exhibit attentional vulnerabilities

Edinburgh scientists solve century-old evolutionary puzzle about malaria parasites

Scientists identify factors that regulate the development of brain cells in a specific order

Combining organoids and microfluidics to study how the immune system responds to hepatitis C

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Researchers discover how an “accordion effect” is vital for switching off genes

Transposons are a potential antibiotic resistance, a study reveals

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

Novel method to obtain genomic data shows potential success

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

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