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Study pinpoints specific genes that cause ovarian cancer

High-grade serious ovarian carcinoma is the fifth major cause of cancer-associated deaths in women in the United States.

14 Sep 2020

Study may lead to future treatments for hearing loss

Scientists have performed a study that has successfully established the role played by a crucial protein in the development of hair cells.

14 Sep 2020

Genomic study can advance wheat research and breeding

The objective of the Seeds of Discovery (SeeD) initiative is to enable the effective application of the genetic diversity of wheat and maize.

14 Sep 2020

Developing computational algorithms to enable a closer look at the 3D genome

Breakthrough advances in biomedical technology have come a long way, especially with three-dimensional mapping of the structure of the genome.

14 Sep 2020

Inherited variation in GATA3 gene associated with relapse in children with leukemia

Scientists at St. Jude Children's Research Hospital are investigating the inherited genetics of childhood leukemia and how particular gene variations can affect treatment outcomes. The research showed that an inherited variation in the GATA3 gene strongly influences early response to chemotherapy and is linked to relapse in children with acute lymphoblastic leukemia (ALL).

14 Sep 2020

Study shows how genetic variants affect gene regulation and contribute to disease risk

The multi-institutional Genotype-Tissue Expression (GTEx) Consortium has published its final series of studies, as part of a final-phase initiative.

14 Sep 2020

Researchers develop new tool to predict protein disorder

Nobel Prize winner Christian Boehmer Anfinsen had demonstrated clearly that a protein is capable of finding its way back to its “native” 3D structure.

11 Sep 2020

Bioengineers detect the presence of maxRNA on the surface of human cells

Bioengineers have demonstrated that RNA produced by the human genome is found on the surface of human cells.

11 Sep 2020

CRISPR in a Box: New educational gene editing tool kit

Introducing CRISPR in a Box™ - it's not a new crunchy cereal or the latest snack - it's an educational tool kit consisting of state-of-the-science gene editing technology that could be coming to a school near you.

10 Sep 2020

Researchers reconstruct the birth of a male sex chromosome in Atlantic herring

The evolution of sex chromosomes is of crucial importance in biology as it stabilises the mechanism underlying sex determination and usually results in an equal sex ratio.

10 Sep 2020

Research shows how mutations in DNA packaging machines can drive cancer development

Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells to control how genes are turned on and made into proteins.

9 Sep 2020

New gene test predicts risk of drug-induced liver injury

Researchers who were exploring ways to establish the feasibility of batches of small liver organoids have now identified a new testing approach.

9 Sep 2020

Zika virus infection during pregnancy can cause severe abnormalities in the fetus

Zika virus infection during pregnancy can cause severe abnormalities in the fetus, including malformations such as microcephaly. In a small proportion of cases, the disease may lead to miscarriage and perinatal death.

4 Sep 2020

Study sheds more light on plant evolution

A study led by researchers from Tasmania, Chile and Germany has furthered our understanding of plant evolution by tracking the origins of electrical signaling components that plants developed to communicate and adapt to life on land.

4 Sep 2020

Gut bacterium is linked to increased risk of stomach cancer

The bacterium Helicobacter pylori is linked to increased risk of stomach cancer, and is genetically highly variable. A new study by researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich explores the role played by this diversity in the early phase of infection in adult humans.

3 Sep 2020

Researchers develop new gene therapy for congenital blindness

Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that targeted activation of genes of similar function can compensate for the primary defect.

3 Sep 2020