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Gut Microbes Transform Excreted Glucose into Crucial Fatty Acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

PanK4 Protein Could Be Key to Better Control of Blood Sugar and Metabolism

Physical activity is not only important for fitness, but also for health. This is confirmed by a new study conducted under the direction of Prof. Dr. Maximilian Kleinert at the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE). His team discovered that the protein PanK4 plays a crucial role in the energy metabolism of skeletal muscles.

13 Feb 2025

New Technology for Visualizing Gene Activity in Single Cells

How do bacteria whether harmless ones residing in human bodies or those causing diseases coordinate their activities?

6 Feb 2025

CRISPR-Engineered Fat Cells Show Promise in Preclinical Cancer Models

Cancer is rarely discussed in the same breath as liposuction or plastic surgery.

5 Feb 2025

New DNA Sequencing Method Revolutionizes Metabolite Measurement

Researchers at the University of Toronto have developed a novel approach to measure metabolites using DNA sequencing.

5 Feb 2025

Gut Microbes May Explain Link Between Sugar-Sweetened Beverages and Diabetes

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear.

3 Feb 2025

New Method Helps T Cells Live Longer and Fight Cancer More Effectively

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

29 Jan 2025

Shade Plants Harness Far-Red Light for Photosynthesis in a Surprising Way

Plants in the shade of other plants receive more light than scientists had previously believed. A team of researchers from Utrecht University and Wageningen University & Research (WUR) describe how, in a recent article in the scientific journal Plant Cell & Environment.

10 Jan 2025

Genetic Discovery Offers Potential for Higher Crop Yields and Biofuel Production

A team of scientists with two Department of Energy Bioenergy Research Centers -; the Center for Bioenergy Innovation, or CBI, at Oak Ridge National Laboratory and the Center for Advanced Bioenergy and Bioproducts Innovation, or CABBI, at the University of Illinois Urbana-Champaign -; identified a gene in a poplar tree that enhances photosynthesis and can boost tree height by about 30% in the field and by as much as 200% in the greenhouse.

6 Jan 2025

Research Reveals Regulatory Role of Glucose-6-Phosphate Dehydrogenase in Mitophagy

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway.

30 Dec 2024

Overactive Chemoreceptors Affect Cardiovascular and Metabolic Consequences of Type 2 Diabetes

Researchers from the University of Missouri are studying potential therapies to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes.

20 Dec 2024

Study Reveals Mechanism Behind T Cells' Cancer-Killing Power in Hypoxia

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective.

16 Dec 2024

Study Offers a New Perspective on the Evolution of Large Human Brains

Brain tissue is among the most energetically costly in the body, and as a result, larger-brained mammals require more energy to support brain growth and maintenance.

3 Dec 2024

Genetic Signatures Driving Early Type 2 Diabetes in South Asians Revealed

A genetic predisposition to having lower insulin production and less healthy fat distribution are major causes of early-onset type 2 diabetes in British Asian people.

28 Nov 2024

New Insights Into the Role of p53 in Intestinal Inflammation

A group of scientists from Charité – Universitätsmedizin and the Berlin Institute for Medical Systems Biology of the Max Delbrück Center have provided fresh insight into the pathophysiology of ulcerative colitis an inflammatory bowel disease that affects an estimated five million people globally and is associated with a higher risk of colon cancer.

28 Oct 2024

Simple Neural Circuit Controls Chewing and Appetite

Speaking, singing, coughing, laughing, yelling, yawning, chewing-;we use our jaws for many purposes. Each action requires a complex coordination of muscles whose activity is managed by neurons in the brain.

24 Oct 2024

Metabolic Profiling of Lung-Resident NK Cells Reveals Novel Therapeutic Targets

Trinity College Dublin researchers, based at St James's Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown, but crucial 'natural killer' (NK) immune cell resident in the lungs.

14 Oct 2024

Unveiling the Protective Role of KLF6 in Diabetic Kidney Disease

Research by Stony Brook Medicine nephrology specialists may help prevent or reduce diabetic kidney disease progression by targeting cellular signaling between kidney cells and inducing a specific gene.

11 Oct 2024

The Role of Yeast Ribosomes in Cellular Survival During Starvation

Researchers from EMBL Heidelberg and the University of Virginia School of Medicine have uncovered a fascinating mechanism by which cells respond to nutrient deprivation. This discovery holds intriguing implications for understanding cancer development.

10 Oct 2024

A Novel Biosensor for Calcium Detection in Fruit Flies, Zebrafish, and Mice

In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes.

23 Sep 2024