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Boosting Post-Transplant Survival: Tailoring Gut Microbiome to Fight GvHD

After stem cell transplantation, the donated immune cells sometimes attack the patients' bodies. This is known as graft versus host disease or GvHD.

9 Jan 2024

Computational Creation of Complex Protein All-α Structures

Based on their amino acid sequences, proteins fold into distinct three-dimensional structures that determine their function. While de novo protein design has advanced significantly, complex all-αproteins, in which α-helices are not stacked in a parallel fashion within three-dimensional structures, have not been as easily designed.

8 Jan 2024

Breakthrough in Bdellovibrio's Prey Recognition System

Researchers from the Universities of Birmingham and Nottingham have uncovered how naturally occurring antimicrobial predatory bacteria, known as Bdellovibrio bacterivorous, produce fiber-like proteins on their surface to entice prey in a study published on January 4th, 2024, in Nature Microbiology.

8 Jan 2024

mEnrich-seq: A High-Specificity Bacterial Enrichment Technique for Microbiome Research

In a landmark study recently published in the journal Nature Methods, researchers at the Icahn School of Medicine at Mount Sinai have unveiled mEnrich-seq-;an innovative method designed to substantially enhance the specificity and efficiency of research into microbiomes, the complex communities of microorganisms that inhabit the human body.

5 Jan 2024

Research Reveals Unforeseen Functions for Autophagy Genes in Neuronal Health and Aging

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions

5 Jan 2024

New Method Designs Proteins With Complex Shapes

A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin.

5 Jan 2024

The Sophisticated Healthcare System of Matabele Ants

The diet of the ubiquitous Matabele ants (Megaponera analis) found south of the Sahara is restricted to termites.

3 Jan 2024

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.

26 Dec 2023

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

26 Dec 2023

New Tool Brings Order to Single-Cell Data Chaos

A new methodology that allows for the categorization and organisation of single-cell data has been launched. It can be used to create a harmonized dataset for the study of human health and disease.

26 Dec 2023

How Next-Gen Sequencing is Revolutionizing Infection Diagnosis

Scientists from Necker-Enfants Malades Hospital (AP-HP), the Institut Pasteur, Université Paris Cité, Inserm, Université Paris-Est Créteil and the Alfort National Veterinary School, coordinated by Professor Marc Eloit and Dr. Anne Jamet in collaboration with Dr. Jacques Fourgeaud and Beatrice Regnault, studied the role of global genetic characterization of samples (or non-targeted metagenomics) using next-generation sequencing (mNGS) in diagnosing infections.

19 Dec 2023

Free AI Drug Discovery Course Surpasses 2,500 Users

An online course on Disease Modeling and Target Discovery launched 7 months ago by clinical stage generative artificial intelligence (AI)-driven biotechnology company Insilico Medicine has surpassed 2,500 users.

12 Dec 2023

Insights into the Shaping and Organization of Microbial Communities

Dental plaque, gut bacteria, and the slick coating on river rocks exemplify biofilms—structured communities of microorganisms that inhabit both human bodies and the surrounding environment.

11 Dec 2023

Evonetix Announces Agreement for Revolutionary Gene Synthesis Platform With Analog Devices

EVONETIX LTD (‘Evonetix’), the company developing semiconductor scale technology to improve access to gene synthesis, today announces the signing of a joint development agreement and commercial supply agreement with Analog Devices, Inc. (ADI), a global semiconductor leader.

6 Dec 2023

Unlocking the Mysteries of Fetal Brain Development

Cheryl Rosenfeld has dedicated three decades to investigating the transmission of biological information from mothers to babies during pregnancy.

6 Dec 2023

A Breakthrough in Combatting Multi-Drug Resistant Bacteria

Healthcare-associated infections pose a widespread challenge in the treatment of suppurating wounds, compounded by the escalating prevalence of multi-drug resistant bacteria.

6 Dec 2023

Brain Cell Genetics Drive Alzheimer's Progression

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

6 Dec 2023

Biomedical Publisher Future Science Group Joins Taylor & Francis

Taylor & Francis’ Support for Scientific and Medical Communities Expanded with Journals, Digital Hubs and Publishing Solutions

5 Dec 2023

Discovery Park Ventures Expands Fund to £3m to Invest in More Innovative Science and Technology Start-Ups

Discovery Park Ventures (DPV) announces the expansion of its early-stage life science fund from £1m to £3m, in order to capitalise on exciting investment opportunities and support its existing portfolio.

5 Dec 2023

A Glimpse into Future: Bioprinted Organs May Become Reality in Two Decades

In recent years, 3D printing has emerged as a transformative technology for the field of organ transplantation. Doctors are already using 3D-printed skin for burn treatment and wound healing, and this year has seen the first successful use of 3D-printed cartilage for ear reconstruction.

22 Nov 2023