Hearing Loss News and Research

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Hearing loss, impairment or deafness may be of two major types: one that develops some time in life, one that a baby is born with – or congenital deafness. Most commonly, hearing loss is seen with age or is caused by exposure to loud noises.

NSL Complex Regulates Intraciliary Transport Genes in Multiple Cell Types

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown in both fruit flies and mammals to regulate the expression of thousands of genes. Abrogation of the NSL genes causes the organism to die, which gives rise to the complex’s unusual name.

28 Aug 2023

Age-Related Hearing Loss Associated With Decrease of Cholesterol in the Inner Ear

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

25 Aug 2023

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

23 Aug 2023

Uncovering the Role of Cochlear Signal in Hearing Loss

A cochlear signal, the precise role of which has been uncertain since its discovery around 70 years ago, probably gives the brain information on whether the ear is working normally or not.

5 Jul 2023

Virally Mediated Gene Therapy Rescues Hearing in Aging Mice

By 2050, one in 10 individuals are expected to live with some form of hearing loss. Of the hundreds of millions of cases of hearing loss affecting individuals worldwide, genetic hearing loss is often the most difficult to treat.

29 May 2023

New Gene Therapy may be on the Horizon for Usher Syndrome Type 1F

Usher Syndrome type 1F is a rare but severe genetic disease that causes deafness, lack of balance, and progressive blindness.

27 Apr 2023

UH Researcher Designs New Model Expressing the Most Common Disease Mutation in USH2A

Usher syndrome, a rare inherited genetic disease, is a leading cause of combined deafness and blindness with type 2A (USH2A) being the most common form.

18 Apr 2023

Identifying mechanisms that may promote hair cell regeneration in mammals

Taking a bite of an apple is considered a healthy choice. But have you ever thought about putting in earplugs before your favorite band takes the stage?

14 Feb 2023

Cochlear organoids provide a platform to understand sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

Benefits of Finnish health research environment for genomic research

New findings from the FinnGen study illustrate the clear advantages of the Finnish health research environment for genomic research.

19 Jan 2023

3D “mini eyes” provide insight into genetically induced blindness

The development of “mini eyes” by researchers at the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) has made it possible to study and comprehend the onset of blindness in the rare genetic disease known as Usher syndrome more.

From University College London 22 Nov 2022

Multidisciplinary analysis of WGS improves diagnostic rates

The NHS Genomic Medicine Service, launched by the Department of Health in the United Kingdom in 2018, enables patients with unusual conditions to have their complete genetic code evaluated in the hopes of gaining a critical diagnosis.

From University College London 8 Nov 2022

Unique combination of transcription factors trigger cell regeneration in zebrafish

Scientists at the National Institutes of Health have identified a particular protein network required for cell regeneration to restore hearing in zebrafish.

From National Human Genome Research Institute (NHGRI) 15 Sep 2022

Researchers analyze and demonstrate how organelles divide into cells

The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.

From University of Exeter 10 Jun 2022

Experts visualize genes linked to hearing loss in humans

Scientists from Uppsala University recently documented and visualized genes linked to hearing loss in the human inner ear.

7 Dec 2021

New microbiome study could enable new treatments for middle ear infections

The main cause of preventable hearing loss and deafness in Indigenous communities is chronic middle ear infections.

10 Nov 2021

SARS-CoV-2 virus may be able to infect the inner ear, study shows

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

1 Nov 2021

Researchers identify the mechanism leading to deafness in Norrie disease

A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.

6 Oct 2021

Gene expression changes help understand the mechanism behind noise-induced hearing loss

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.

30 Sep 2021