Hearing loss, impairment or deafness may be of two major types: one that develops some time in life, one that a baby is born with – or congenital deafness. Most commonly, hearing loss is seen with age or is caused by exposure to loud noises.
The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown in both fruit flies and mammals to regulate the expression of thousands of genes. Abrogation of the NSL genes causes the organism to die, which gives rise to the complex’s unusual name.
Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.
In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).
A cochlear signal, the precise role of which has been uncertain since its discovery around 70 years ago, probably gives the brain information on whether the ear is working normally or not.
By 2050, one in 10 individuals are expected to live with some form of hearing loss. Of the hundreds of millions of cases of hearing loss affecting individuals worldwide, genetic hearing loss is often the most difficult to treat.
Usher Syndrome type 1F is a rare but severe genetic disease that causes deafness, lack of balance, and progressive blindness.
Usher syndrome, a rare inherited genetic disease, is a leading cause of combined deafness and blindness with type 2A (USH2A) being the most common form.
Taking a bite of an apple is considered a healthy choice. But have you ever thought about putting in earplugs before your favorite band takes the stage?
Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.
New findings from the FinnGen study illustrate the clear advantages of the Finnish health research environment for genomic research.
The development of “mini eyes” by researchers at the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) has made it possible to study and comprehend the onset of blindness in the rare genetic disease known as Usher syndrome more.
The NHS Genomic Medicine Service, launched by the Department of Health in the United Kingdom in 2018, enables patients with unusual conditions to have their complete genetic code evaluated in the hopes of gaining a critical diagnosis.
Scientists at the National Institutes of Health have identified a particular protein network required for cell regeneration to restore hearing in zebrafish.
The research, headed by Professor Michael Schrader of the University of Exeter, looked at peroxisome dynamics and discovered new ways for them to divide.
Scientists from Uppsala University recently documented and visualized genes linked to hearing loss in the human inner ear.
The main cause of preventable hearing loss and deafness in Indigenous communities is chronic middle ear infections.
Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.
A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.
A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.
New research offers insight into the origins of the 2012 Bundibugyo viral disease outbreak in the Democratic Republic of the Congo.