Herpes simplex is a viral disease caused by herpes simplex viruses; both herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2) cause herpes simplex. Infection with the herpes virus is categorized into one of several distinct disorders based on the site of infection.
Recent research by scientists from the University of Illinois demonstrates a process that halts the herpes simplex virus 1 from inducing severe brain damage and death.
Immunologists discovered how immune sensors in infected cells organize and initiate an immune response to infections with living bacteria and viruses.
In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.
Scientists from the University of Illinois Chicago (UIC) have found that heparanase (HPSE) is an important regulator of innate defense mechanisms of cells.
Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.
A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.
A new study shows how the immune system has a damaging effect on a severe brain condition, which is most commonly caused by the cold sore virus.
The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule. Now, UT Southwestern scientists have revealed that STING also activates a separate pathway, one that directly kills tumor-fighting immune cells.
Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.
Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans.
VRAC/LRRC8 chloride channels play a crucial role in the transport of neurotransmitters, amino acids, and cytostatics.