Immunology News and Research

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Immunology is the study of the body's immune system.

IgA Described as "Tuner" in Microbe Interaction Regulation

Throughout the world, IgA deficiency is considered to be the most common primary immune deficiency, but its presentation has continued to confuse researchers and physicians.

29 May 2023

Study Characterizes the Properties of MAIT Cells in Mouse Lung

A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike.

26 May 2023

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

23 May 2023

'Lost' Immune Cells Could be Partly Blamed for Impaired Vaccine Responses During Aging

Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.

23 May 2023

Novel Gene-Editing Strategy Harnesses Unusual Protective Ability to Eliminate HIV-1 Infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

22 May 2023

Scarring on the Extracellular Matrix Causes Muscles to Stop Working in Duchenne Muscular Dystrophy

Muscles that ache after a hard workout usually don't hurt for long, thanks to stem cells that rush to the injured site along "collagen highways" within the muscle and repair the damaged tissue.

12 May 2023

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

The immune system has a biological telecommunications system -; small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

8 May 2023

New Insights on Cases of Post-Vaccine Heart Inflammation

Public health experts discovered an increase in cases of myocarditis, an inflammation of heart muscle, after the introduction of the new COVID-19 vaccinations two years ago, particularly in young males who had received mRNA vaccines.

8 May 2023

Innate Tumor Suppression Mechanism Uncovered

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Immune Evasion Mechanism of TNBC Cells Discovered

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

5 May 2023

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients.

4 May 2023

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

2 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

3D Genome Mapping may Lead to Targeted Therapeutic Options for Ependymoma

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

28 Apr 2023

Some Promising Human Antibodies can Fight New Variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

27 Apr 2023

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

A breakthrough in gene variants of an inflammation “brake” brings researchers one step closer to developing personalized treatments for those at risk of kidney disease and kidney failure.

26 Apr 2023

Study Provides Insight into the Formation of Protective Memory T Cells Against Salmonella

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Microbial Drought Resistance Could Result in Soil Carbon Losses

Soil stores more carbon than plants and the atmosphere combined, and soil microbes are largely responsible for putting it there.

13 Apr 2023

Immunotherapy Response in Advanced Melanoma: Effect of Previous Treatments

According to a study conducted by UCLA, patients with advanced melanoma responded differently to PD-1 checkpoint blockade immunotherapy depending on a variety of variables, including whether or not they had previously received CTLA-4 blockade, another type of immunotherapy.

11 Apr 2023