Immunology News and Research

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Immunology is the study of the body's immune system.

Commonly used antidepressant drugs can also help the immune system to attack cancer

A class of drug called monoamine oxidase inhibitors is commonly prescribed to treat depression; the medications work by boosting levels of serotonin, the brain's "happiness hormone."

10 Jun 2021

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP).

8 Jun 2021

Antibody treatment reactivates the immune defense in advanced-stage cancer patients

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer. The treatment alters the function of the body's phagocytes and facilitates extensive activation of the immune system.

4 Jun 2021

NCI grants over $4.2 million to launch the Cancer Epitope Database and Analysis Resource

Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.

3 Jun 2021

Researchers discover what fuels the immune system’s “natural killers”

Natural killer (NK) cells, while having a name straight out of a Tarantino film, are allies of humans when it comes to combating cancer and infections.

3 Jun 2021

New consortium of bacteria can be used to treat aggressive colitis in humanized mouse models

A new study reported in Nature Communications shows that a consortium of bacteria, developed to complement lacking or poorly represented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, inhibited and treated chronic immune-mediated colitis in humanized mouse models.

31 May 2021

Novel drug is highly effective in preventing severe COVID-19 in mice

The drug diABZI -- which activates the body's innate immune response -- was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2,

31 May 2021

New wiki promotes development of innovative saliva-based diagnostic tests and customized treatment

The NIDCR has funded the creation of the Human Salivary Proteome Wiki, the first public platform that organizes information on each of the proteins found in human saliva.

27 May 2021

Study finds unique molecular mechanism by which Hepatitis C virus evades host’s immune system

Hepatitis C virus (HCV) can cause chronic liver infection, which can lead to irreparable liver damage and liver cancer.

27 May 2021

Neutralizing antibodies are produced after SARS-CoV-2 infection

A research group from Osaka University led by Professor Hisashi Arase and consisting of researchers from the Research Institute for Microbial Diseases, the Institute for Protein Research, the Immunology Frontier Research Center, the Center for Infectious Diseases, and the Graduate School of Medicine has discovered for the first time that both neutralizing antibodies that protect against infection as well as infection-enhancing antibodies that increase infectivity are produced after infection with SARS-CoV-2 by analyzing antibodies derived from COVID-19 patients.

26 May 2021

Three-dimensional organization of genome is extremely dynamic during gamete formation

Inside the nuclei of cells, the genome is tightly organized (packaged). This three-dimensional (3D) genome organization is basic because it controls gene expression.

21 May 2021

High-fat, high-sugar diet reduces intestinal immune cell activity in mice

A team of researchers led by Thaddeus Stappenbeck discovered that a high-fat, high-sugar diet relates to reduced intestinal immune cell activity in mice.

20 May 2021

New kind of biomolecule could play a vital role in the biology of all living things

Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.

18 May 2021

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells produce antibodies in response to a pathogen or a vaccine, providing immunity.

14 May 2021

Food dyes may cause disease when the immune system is dysregulated

Artificial food colorants can cause disease when the immune system has become dysregulated, Icahn School of Medicine at Mount Sinai researchers report.

14 May 2021

Genomic Analysis for the Conservation of Koalas

In this interview, AZoLifeSciences speaks to Professor Parwinder Kaur about her latest research that uses genomic analysis for the conservation of koalas.

10 May 2021

Study shows how T cells detect dangerous invaders in the human body

T-cells are known to play a crucial role in the human immune system.

7 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

New genetic database maps how immune disorders evolve

A first-of-its-kind genetic database for autoinflammatory and autoimmune disorders has been created by Japanese researchers.