Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

New drug delivery strategy could make it easier for patients to take their medications

In recent years, scientists have developed monoclonal antibodies -; proteins that mimic the body's own immune defenses -; that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn's disease.

31 Aug 2021

Study explores the link between antibiotics use, gut microbiota, and lifespan

A group of scientists have identified a connection between the type of microbiome that recolonizes the gut after antibiotics and the lessened lifespan in mice.

31 Aug 2021

Study analyzes the health benefits of time-restricted eating

Time-restricted eating (TRE) is a dietary regimen in which eating is restricted to particular hours. It has received great attention in weight-loss circles.

19 Aug 2021

Cytokines play a role in regulation of beige fat

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

6 Aug 2021

Largest study identifies causal genetic variants associated with type 1 diabetes risk

Scientists have completed the largest and most diverse genetic study of type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.

23 Jul 2021

Ethnically diverse genetic study expands understanding about potential causes of type 2 diabetes

Researchers at the Keck School of Medicine (KSOM) of USC are among the contributors to a large-scale ethnically diverse genetic study that has expanded what we know about potential causes of type 2 diabetes.

15 Jun 2021

Some Type 2 diabetes patients could benefit from bone marrow stem cell transplants, study shows

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

4 Jun 2021

Daily intake of fruits can lower risk of type 2 diabetes

Eating at least two serves of fruit daily has been linked with 36 percent lower odds of developing type 2 diabetes, a new Edith Cowan University (ECU) study has found.

3 Jun 2021

Life expectancy can be increased by an average of 30% in transgenic mice, study shows

Aging is associated with an overall decline in health and increased frailty, and is a major risk factor for multiple chronic diseases.

2 Jun 2021

Studies highlight different aspects of link between obesity and cancer

Multi-factorial metabolic and inflammatory abnormalities in obesity, independently or in combination, seems to be the critical biological link of obesity, cancer and racial/gender health disparities. However, the specific cross-talk between these factors remain elusive.

24 May 2021

Study identifies predictive causal role for specific cell types in type 1 diabetes

Researchers revealed a predicted causative role for certain cell types in type 1 diabetes by examining its genetic foundations.

From UC San Diego 20 May 2021

Processed diet reduces gut bacteria and promotes encroachment of microbiota into the intestine

Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

29 Apr 2021

New gene editing approach bypasses disease-causing mutations

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

From Penn State University 22 Apr 2021

Obesity reduces mitochondrial gene expression in fat tissues

A university has recently completed a study that suggests that the machinery responsible for handling the energy in fat tissues is performing poorly in obesity.

12 Apr 2021

Novel device can help treat type I diabetes mellitus

Type I Diabetes Mellitus, also called T1D, is an autoimmune disorder that results in an irreversible loss of insulin-producing beta-cells found in the pancreas.

2 Apr 2021

New AI-based method can lead to faster, low-cost development of protein-based drugs

Thanks to a newly published study by scientists, artificial intelligence (AI) can now create novel and functionally active proteins.

1 Apr 2021

Lowering apolipoprotein CIII levels can prevent deleterious effects of a high-fat diet

Consumption of a diet with high fat levels increases the risk of fatty liver, obesity, cardiovascular diseases, and type 2 diabetes.

15 Mar 2021

UMD awarded grant to explore nettle as a functional food for improving health

Obesity, diabetes, and overall immune system health are issues that are all top-of-mind right now, especially during the pandemic.

9 Mar 2021

Researchers use unique methods to map the mechanism behind cellular communication

A better understanding of cellular interactions is crucial to interpret several biological diseases and systems.

15 Feb 2021

An outlook on latest trends in peptide drug discovery and development

Currently, there are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of diseases such as diabetes, cancer, hormone disorders, HIV infection, and multiple sclerosis.

11 Feb 2021