Laboratory News and Research

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New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections. Researchers have now discovered that a new class of oral drugs that acts directly on human cells can inhibit a diverse range of pathogenic SARS-CoV-2 strains.

13 Mar 2023

Study identifies previously unknown cell types that drive the onset of osteoarthritis

A Michigan Medicine study has identified a new potential target for treating osteoarthritis – a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.

10 Mar 2023

Study shows link between a mitochondrial metabolite and activation of inflammatory response

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

9 Mar 2023

Understanding gas transfer between the atmosphere and ocean can lead to better climate models

The injection of bubbles from waves breaking in turbulent and cold high-latitude regions of the high seas is an underappreciated way in which atmospheric gases are transported into the interior ocean.

8 Mar 2023

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

8 Mar 2023

Analyzing microscopic chalk disks coccoliths formed by the marine algae

Under the guidance of Rutgers University, a research group learning about virus-host interactions of worldwide abundant and armor-plated marine algae, Emiliania huxleyi, has discovered that the circular and chalk plates produced by the algae have the potential to serve as catalysts for viral infection.

From Rutgers University 7 Mar 2023

First wiring map of neurons in insect brain complete

Researchers have built the first ever map showing every single neuron and how they’re wired together in the brain of the fruit fly larva.

6 Mar 2023

New insights into the underlying mechanism that causes arrhythmogenic cardiomyopathy

Researchers from the group of Eva van Rooij in collaboration with the UMC Utrecht identified a new mutation that leads to the cardiac disease arrhythmogenic cardiomyopathy (ACM).

3 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

New technique may offer a pathway to treat undruggable diseases

Certain diseases, including Alzheimer's, are currently considered "undruggable" because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses.

2 Mar 2023

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the commercial launch of the PhysioMimix™ Single-organ Higher Throughput (HT) System.

From CN Bio Innovations Limited 28 Feb 2023

Nanosatellite paves the way for developing RNA-based medicines

Researchers from Aarhus University and Berkeley Laboratory have designed RNA molecules, that folds into nanoscale rectangles, cylinders, and satellites, and have studied their 3D structure and dynamics with advanced nanotechnological methods.

28 Feb 2023

Cell therapy trial promises long-term improvement for patients with chronic heart failure

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

28 Feb 2023

Study shows how pesticides render certain strawberries bland

Have you ever bitten into a plump, red strawberry, only to find it bland and watery? Certain pesticides might be responsible. A team reporting in ACS' Journal of Agricultural and Food Chemistry has found that two common strawberry fungicides can impact cellular mechanisms, creating berries with subdued flavor and sweetness, as well as a lower nutritional value.

28 Feb 2023

Voluntary initiatives to promote the replacement of lead in UK game hunting are not very effective

Three years into a five-year pledge to completely phase out lead shot in UK game hunting, a Cambridge study finds that 94% of pheasants on sale for human consumption were killed using lead.

27 Feb 2023

Study highlights key role of group 2 innate lymphoid cells in shaping the alveolar niche

A study conducted by researchers at the University of Liège on group 2 innate lymphoid cells (or ILC2s) shows that the functional reprogramming of these cells following their exposure to viruses allows our body to react differently to exposure to certain respiratory allergens.

27 Feb 2023

New molecular understanding of how head injury may contribute to glioma risk

Researchers from the UCL Cancer Institute have provided important molecular understanding of how injury may contribute to the development of a relatively rare but often aggressive form of brain tumor called a glioma.

27 Feb 2023

Study shows why a specific gene mutation has opposite effects on mice and human cancers

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

27 Feb 2023

Researchers tease apart the molecular components involved in abdominal aneurysms

When the artery that supplies the stomach and the liver forms a bulge that ruptures, this medical emergency results in the deaths of 50 percent of patients before they reach the hospital.

24 Feb 2023

Discovery of a lung stem cell subset provides opportunity for new COPD treatments

Respiratory viral infections pose significant morbidity and mortality to patients with chronic lung diseases like emphysema and COPD, causing exacerbations that drive destruction of normal lung tissue, and leading to one of the most common diagnoses for hospital admissions.

24 Feb 2023

Laboratory News and Research

New class of oral drugs inhibits a diverse range of SARS-CoV-2 strains

Study identifies previously unknown cell types that drive the onset of osteoarthritis

Study shows link between a mitochondrial metabolite and activation of inflammatory response

Understanding gas transfer between the atmosphere and ocean can lead to better climate models

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Analyzing microscopic chalk disks coccoliths formed by the marine algae

First wiring map of neurons in insect brain complete

New insights into the underlying mechanism that causes arrhythmogenic cardiomyopathy

Using nanoparticles to carry drugs across the blood-brain barrier

New technique may offer a pathway to treat undruggable diseases

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

Nanosatellite paves the way for developing RNA-based medicines

Cell therapy trial promises long-term improvement for patients with chronic heart failure

Study shows how pesticides render certain strawberries bland

Voluntary initiatives to promote the replacement of lead in UK game hunting are not very effective

Study highlights key role of group 2 innate lymphoid cells in shaping the alveolar niche

New molecular understanding of how head injury may contribute to glioma risk

Study shows why a specific gene mutation has opposite effects on mice and human cancers

Researchers tease apart the molecular components involved in abdominal aneurysms

Discovery of a lung stem cell subset provides opportunity for new COPD treatments

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