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Epidemiology and Genetic Underpinnings of Clonal Hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

3D Bioprinting Technology Developed to Eliminate Cancer Cells

A three-dimensional (3D) bioprinting technology capable of eliminating cancer cells using the function of immune cells has been developed for the first time in the world.

12 Jul 2023

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

The immune system has a biological telecommunications system -; small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

8 May 2023

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

8 Mar 2023

Researchers reveal link immune system genetics and a person's ability to resist new COVID-19 variants

An international team including researchers from the HSE University Faculty of Biology and Biotechnology has found a link between certain genetic features of the immune system and one's ability to effectively resist new waves of COVID-19.

17 Feb 2023

Study findings may pave way for personalized cancer treatment

In a step likely to advance personalized cancer treatment, scientists have for the first time shown in patients that levels of biomarkers are not enough to tell which patients are likely to respond best to immunotherapy.

31 Jan 2023

Immunity to the SARS-CoV-2 virus likely to protect against omicron

People who developed immunity to SARS-CoV-2, either by vaccination or contact, are expected to get some protection against the pathogen’s omicron version.

16 Mar 2022

L452R mutation of SARS-CoV-2 spike protein is involved in cellular immunity evasion

A research team has demonstrated that the L452R mutation of the SARS-CoV-2 spike protein plays a role in cellular immunity evasion.

21 Jul 2021

Study shows that Bubonic Plague had a long-term impact on immune gene expression

A new study shows that the Bubonic Plague has had a long-term impact on immune gene expression.

20 May 2021

Study suggests that bubonic plague had long-term impact on human immune genes

Scientists examining the remains of 36 bubonic plague victims from a 16th century mass grave in Germany have found the first evidence that evolutionary adaptive processes, driven by the disease, may have conferred immunity on later generations of people from the region.

7 May 2021

New breakthrough in understanding the role of high-risk immune genes in rheumatoid arthritis

Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA).

19 Apr 2021

New label-free immune profiling assay to assess rapidly changing host immune response

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a new label-free immune profiling assay that profiles the rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves, which can often be at low levels within a host.

26 Mar 2021

Immune receptor proteins can help treat autoimmune diseases

TARM1 is a receptor protein, whose function in the working of the immune system is not known yet. Now, in a new research work, Japanese researchers have analyzed mouse models to investigate the promising role of TARM1 protein in the pathogenesis of rheumatoid arthritis.

From Tokyo University of Science 18 Mar 2021

Mutant peptides derived from SARS-CoV-2 hamper activation of CD8+ killer T cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

5 Mar 2021

Genes inherited from parents are responsible for severe COVID-19

For the first time, scientists have discovered the genetic predisposition of severe COVID-19 disease.

24 Feb 2021

Study sheds new light on penicillin allergy

Scientists have reported the first strong evidence of the role of HLA-B, a crucial histocompatibility complex gene, in penicillin allergy.

27 Oct 2020

Researchers identify the targets of immune rejection

Human pluripotent stem cells (hPSCs) show promise in regenerative medicine for how they lead to the fraction of every other type of cells in the body.

17 Sep 2020

Researchers identify phosphoprotein biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

29 Jul 2020

Study shows neo-self antibody as major cause of recurrent pregnancy loss

A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss.

23 Jul 2020

Study provides roadmap for developing effective vaccine against Staphylococcal infections

Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.

1 Jul 2020