A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.
Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.
A research team comprising members from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has made a groundbreaking discovery, highlighting the central role of macrophages in the regeneration of intestinal cells.
Our cells have a fleet of 300 molecular machines, called cullin-RING ligases, or "CRLs" for short, that each is capable of triggering destruction of specific proteins for the well-being of our cells.
In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).
Obesity is on the rise in the US, which is linked to worse health outcomes and a lower quality of life. Over 30% of American individuals are currently considered fat. Obesity is a significant and expanding public health issue since it is a risk factor for several diseases, including diabetes, cardiovascular disease, and COVID-19.
Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin and the Centre for Genomic Regulation (CRG) in Barcelona have discovered how cells speed changes to their identity known as “cell fate conversion.”
Macrophages, a type of white blood cell, defend the body by engulfing and digesting foreign particles, such as bacteria, viruses, and dead cells.
Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to edema and ascites.
Carbon nanotubes (CNTs) are novel nanomaterials with potential uses in a variety of sectors. However, the harm they represent to people is unknown, and studies have revealed that multiwalled CNTs cause an immune response in mice.
Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.
M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis.
A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.
To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.
The removal of obsolete and damaged cell components by the body is crucial for fighting diseases like tuberculosis (TB), which establish themselves inside human cells, according to researchers from the Francis Crick Institute.
Most immunotherapies that aim to increase T cell activity are ineffective in treating estrogen receptor-positive (ER+) breast cancer. A new study of invasive ER+ breast cancers led by researchers at the University of Pittsburgh School of Medicine implies that targeting a different type of immune cell called macrophages may be a more effective approach.
Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer.
A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.
For almost 140 years, the origin and behavior of an enigmatic cell type inside lymph nodes, called a tingible body macrophage, has remained a mystery.
Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.
Thanks to a new prognostic method for detecting cancers including cancer of the large intestine, doctors could provide clearer disease prognoses and predict which patients will respond best to immunotherapy.