Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Researchers identify changes in gene expression and cellular interactions in COPD lung cells

Researchers at Baylor College of Medicine, Yale University and other institutions have identified previously unrecognized changes in gene expression and cellular interactions in distinct cell populations in chronic obstructive pulmonary disease (COPD).

28 Jan 2022

Immune cells in arteries can sniff out their surroundings and cause inflammation

An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.

17 Jan 2022

Research sheds new insights into development of lung macrophages in humans

The lungs are exposed to microorganisms like viruses and bacteria from the moment of the first breath.

13 Jan 2022

Scientists use fruit fly embryos to study immune cell invasion

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

7 Jan 2022

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

Apoptosis of mesenchymal stromal cells benefits therapeutic function

Scientists recently identified the therapeutic benefits to patients receiving mesenchymal stromal cell (MSC) therapy.

15 Nov 2021

Experts identify novel mechanisms involved in macrophage polarization

Macrophages are important cells of the immune system with numerous beneficial functions. However, macrophages also aggravate common diseases.

8 Nov 2021

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed macrophage–tumor chimeric exosomes that co-activate the immune response and tumor microenvironment to support cancer immunotherapy.

18 Oct 2021

Newly identified antibacterial mechanism could inspire novel strategies to combat bacterial pathogens

Similar to how a spider traps its prey, the cells of the human immune system cooperate to trap and “eat” bacteria.

14 Sep 2021

Cytokines play a role in regulation of beige fat

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

6 Aug 2021

Cell-analysis method could pave the way for new strategies to fight tuberculosis

A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world.

23 Jul 2021

Scientists are paving the way for cancer treatments with fewer side effects

In recent years, immunotherapy has revolutionized the field of cancer treatment. However, inflammatory reactions in healthy tissues frequently trigger side effects that can be serious and lead to the permanent discontinuation of treatment.

5 Jul 2021

Antibody treatment reactivates the immune defense in advanced-stage cancer patients

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer. The treatment alters the function of the body's phagocytes and facilitates extensive activation of the immune system.

4 Jun 2021

Scientists identify the language the body uses to marshal responses to threats

UCLA life scientists have identified six "words" that specific immune cells use to call up immune defense genes -- an important step toward understanding the language the body uses to marshal responses to threats.

13 May 2021

Study identifies molecular mechanism by which HSPCs recover after chemotherapy-induced injury

Chemotherapy has a damaging effect on hematopoietic stem and progenitor cells (HSPCs) in bone marrow. However, once chemotherapy ends, HSPCs regenerate, a process that has remained unknown--until now.

From Osaka University 8 Mar 2021

Oncotarget review highlights molecular connections between cancer stem cells and macrophages

Oncotarget published "Cancer stem cells and macrophages: molecular connections and future perspectives against cancer" which reported that Cancer stem cells have been considered the key drivers of cancer initiation and progression due to their unlimited self-renewal capacity and their ability to induce tumor formation.

17 Feb 2021

Macrophage News and Research

Researchers identify changes in gene expression and cellular interactions in COPD lung cells

Immune cells in arteries can sniff out their surroundings and cause inflammation

Research sheds new insights into development of lung macrophages in humans

Scientists use fruit fly embryos to study immune cell invasion

Treatment with common allergy medication linked to improved immunotherapy response

Apoptosis of mesenchymal stromal cells benefits therapeutic function

Experts identify novel mechanisms involved in macrophage polarization

Researchers develop chimeric exosomes that co-activate immune response and tumor microenvironment

Newly identified antibacterial mechanism could inspire novel strategies to combat bacterial pathogens

Cytokines play a role in regulation of beige fat

Cell-analysis method could pave the way for new strategies to fight tuberculosis

Scientists are paving the way for cancer treatments with fewer side effects

Antibody treatment reactivates the immune defense in advanced-stage cancer patients

Scientists identify the language the body uses to marshal responses to threats

Study identifies molecular mechanism by which HSPCs recover after chemotherapy-induced injury

Oncotarget review highlights molecular connections between cancer stem cells and macrophages

Noncoding RNA plays key role in sepsis, regulates inflammatory gene expression

Circadian rhythms control killer cells in the immune system

Researchers discover protein that may trigger lung scarring

Discovering a new step in immune cell generation

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