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Hematopoietic stem cells play key focus of stem-cell-based medical research

According to a recent study, a protein that controls how DNA is wrapped within chromosomes plays a key role in the proper functioning of blood stem cells.

2 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Mother's unhealthy vaginal microbiome may contribute to mortality and altered development in babies

A new study in mice from University of Maryland School of Medicine researchers showed that an unhealthy vaginal microbiome in pregnant mothers in combination with an unhealthy diet contributed to increased pup deaths and altered development in the surviving babies.

28 Jan 2022

An Interview with The Million Veteran Program (MVP)

In this interview, we speak to Dr. Sumitra Muralidhar, the Program Director for VA’s Million Veteran Program (MVP) about the program and its aims for veterans.

28 Jan 2022

Stanford study reveals how ribosomes may contribute to age-related diseases

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein folding.

20 Jan 2022

Coffee found to have a stimulating effect on some digestive processes

A new scientific review, published in Nutrients, highlights coffee's effects on digestion and the gut, and its impact on organs involved in digestion.

19 Jan 2022

Columbia researchers develop new blood test to measure the pace of biological aging

Researchers at Columbia University Mailman School of Public Health have developed a new blood test to measure the pace of biological aging. Based on an analysis of chemical tags on the DNA contained in white blood cells, called DNA methylation marks, the new test is named DunedinPACE, after the Dunedin Birth Cohort used to develop it.

19 Jan 2022

First molecular images of enzyme may help solve the mystery cause of hereditary neurodegenerative diseases

WEHI researchers have produced the first molecular images of an enzyme that controls proteins to signal and communicate with each other in human cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 13 Jan 2022

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

12 Jan 2022

Neurons derived from human stem cells can predict the cardinal features of psychiatric illness

In a breakthrough that holds significant promise for early diagnosis and better treatment of psychiatric illness, researchers have for the first time used neurons derived from human stem cells to predict the cardinal features of a psychiatric illness, such as psychosis and cognitive deficits in patients with schizophrenia.

11 Jan 2022

A folic acid-like drug changes a DNA process within brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

From Vanderbilt University 6 Jan 2022

Study reveals a tug-of-war between genes inherited from the father and the mother

Cambridge scientists have identified a key signal that the fetus uses to control its supply of nutrients from the placenta, revealing a tug-of-war between genes inherited from the father and from the mother. The study, carried out in mice, could help explain why some babies grow poorly in the womb.

28 Dec 2021

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

24 Dec 2021

Researchers develop novel technique to monitor remote immune mechanisms

The human immune system works hard to maintain an individual’s health and protect against viruses, bacteria, parasites, fungi, and cancerous cells.

17 Dec 2021

Study finding helps better comprehend necroptosis for treating diseases

A group of scientists from WEHI, for the first time, visualized a human cell death complex associated with autoimmune and inflammatory conditions.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 14 Dec 2021

Infant's immune system may be better than the adult immune system

As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Study shows how proteases help keep cells clean

Waste collectors collect and dispose of household waste. In cells, a similar process works to eliminate damaged and potentially hazardous proteins.

13 Dec 2021

First molecular structure of TDP-43 could pave the way for new ALS therapies

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Medical Research News and Research

Hematopoietic stem cells play key focus of stem-cell-based medical research

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

Mother's unhealthy vaginal microbiome may contribute to mortality and altered development in babies

An Interview with The Million Veteran Program (MVP)

Stanford study reveals how ribosomes may contribute to age-related diseases

Coffee found to have a stimulating effect on some digestive processes

Columbia researchers develop new blood test to measure the pace of biological aging

First molecular images of enzyme may help solve the mystery cause of hereditary neurodegenerative diseases

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Neurons derived from human stem cells can predict the cardinal features of psychiatric illness

A folic acid-like drug changes a DNA process within brain tumors

Study reveals a tug-of-war between genes inherited from the father and the mother

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Researchers develop novel technique to monitor remote immune mechanisms

Study finding helps better comprehend necroptosis for treating diseases

Infant's immune system may be better than the adult immune system

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Study shows how proteases help keep cells clean

First molecular structure of TDP-43 could pave the way for new ALS therapies

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