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Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that that high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2, the virus that causes COVID-19.

20 Aug 2020

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

20 Aug 2020

A new scientific method approved for measuring flavanols,procyanidins in cocoa-based products

AOAC INTERNATIONAL today announced the approval of a new scientific method for measuring flavanols and procyanidins in cocoa powders, cocoa liquors, chocolates and cocoa extracts.

19 Aug 2020

Drugs designed to lower alpha-ketoglutarate levels could help fight DIPG tumors

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures.

19 Aug 2020

Protein produced by nervous system may be the key to treating inflammatory diseases

A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).

18 Aug 2020

Researchers show how two X chromosomes communicate during embryo development

Researchers at Massachusetts General Hospital (MGH) have solved a mystery that has long puzzled scientists: How do the bodies of female humans and all other mammals decide which of the two X chromosomes it carries in each cell should be active and which one should be silent?

18 Aug 2020

Single-cell analysis uncovers new details concerning mitochondrial diseases

Investigators led by a team at Massachusetts General Hospital (MGH) have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases-- inherited disorders that interfere with energy production in the body and currently have no cure.

14 Aug 2020

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Aspirin may increase risk of disease progression in older adults with advanced cancer

Results from a recent clinical trial indicate that for older adults with advanced cancer, initiating aspirin may increase their risk of disease progression and early death.

11 Aug 2020

Gene therapy to the inner retina prevents blindness in Cln3-deficient mice

Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease.

11 Aug 2020

UC Riverside physicist receives NIH grant to study how pathogens evolve

For several years, physicist John Barton at the University of California, Riverside, has been working on developing models to understand and predict how pathogens, such as HIV, evolve. This research pursuit has just received support from the National Institutes of Health.

11 Aug 2020

Synthetic peptide makes multidrug-resistant bacteria sensitive to antibiotics

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

7 Aug 2020

Rutgers expert highlights the effects of climate change on allergies, autoimmunity and the microbiome

Climate change and disruption of the ecosystem have the potential to profoundly impact the human body. Xue Ming, professor of neurology at Rutgers New Jersey Medical School, who recently published a paper in the International Journal of Environmental Research and Public Health on the effects of climate change on allergies, autoimmunity and the microbiome -- the beneficial microorganisms that live on and inside the human body -- discusses how the delicate balance of the environment affects conditions such as allergies, autism and immune disorders.

6 Aug 2020

Medical School News and Research

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

A new scientific method approved for measuring flavanols,procyanidins in cocoa-based products

Drugs designed to lower alpha-ketoglutarate levels could help fight DIPG tumors

Protein produced by nervous system may be the key to treating inflammatory diseases

Researchers show how two X chromosomes communicate during embryo development

Single-cell analysis uncovers new details concerning mitochondrial diseases

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

Aspirin may increase risk of disease progression in older adults with advanced cancer

Gene therapy to the inner retina prevents blindness in Cln3-deficient mice

UC Riverside physicist receives NIH grant to study how pathogens evolve

Synthetic peptide makes multidrug-resistant bacteria sensitive to antibiotics

Rutgers expert highlights the effects of climate change on allergies, autoimmunity and the microbiome

Researchers discover genetic cause of severe auto inflammatory syndrome

Identifying a new genetic cause of inherited neuropathy

Rapid drug development yields potential treatment for yellow fever

Scientists use computational biology to identify functional elements in the human genome

Grotesque side effects from unproven stem cell therapies more common than thought

Researchers uncover a novel mechanism by which cancer cells adapt to stress

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

Discovering a new genetic mutation in Schizophrenia

Developing a new CRISPR technique

Monitoring pollen levels using environmental DNA

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