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Automated electron microscopy helps visualize neural function and behavior

Researchers are still clueless about how the neural networks are linked together to make functional circuits.

12 Jan 2021

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

CAR T cells are a breakthrough class of effective but often toxic cancer therapies. To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug.

7 Jan 2021

Study reveals lower transfer of protective SARS-CoV-2 antibodies via the placenta

Recent analyses indicate that pregnant women and newborns may face elevated risks of developing more severe cases of COVID-19 following SARS-CoV-2 infection.

24 Dec 2020

Scientists find new way to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

18 Dec 2020

Gene expression database sheds light on pneumococcal infection

Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome).

16 Dec 2020

New gene therapy approach can improve uterine blood flow in placental insufficiency

A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency, as reported in the peer-reviewed journal Human Gene Therapy.

16 Dec 2020

Researchers provide a list of genes implicated in congenital heart disease

Over two million babies, children, and adults in the United States are living with congenital heart disease--a range of birth defects affecting the heart's structure or function.

15 Dec 2020

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers.

11 Dec 2020

Study sheds light on molecular underpinnings of long-term memory

On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery.

10 Dec 2020

Obesity allows cancer cells to outcompete tumor-killing immune cells, study finds

Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival.

10 Dec 2020

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

According to a new study, a novel T cell genetically engineered by scientists from The University of Arizona Health Sciences can target and attack pathogenic T cells that are responsible for causing Type 1 diabetes. These latest findings may result in new immunotherapy therapies.

7 Dec 2020

Researchers determine 3D structures of RNA hybridization with artificial nucleic acids

As medical research progresses, traditional treatment protocols are being rapidly exhausted. New approaches to treat diseases that do not respond to conventional drugs are the need of the hour.

4 Dec 2020

Specific immune mechanism in COVID-19 patients triggers inflammatory process

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

3 Dec 2020

Research may lead to new strategies for calcium malabsorption

A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role.

2 Dec 2020

Study: Gut microbiota directly shapes the makeup of human immune system

In recent years, the microbiota -- the community of bacteria and other microorganisms that live on and in the human body -- has captured the attention of scientists and the public, in part because it's become easier to study. It has been linked to many aspects of human health.

1 Dec 2020

Researchers identify new gene involved in neurodevelopmental disorders

Researchers and physicians constantly search for novel disease genes that can allow them to figure out why medical problems are not diagnosed in patients.

24 Nov 2020

Adipose tissue plays key role in the aggravation of COVID-19

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

23 Nov 2020