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New computer model helps identify mutations that drive tumor growth

Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

22 Jun 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

27 May 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Research may lead to new therapies for metabolic disorders and other diseases

Researchers at UT Southwestern have uncovered a molecular path that allows cells to detect when their lipid supplies are running low, triggering a flurry of activity that avoids starvation.

23 May 2022

Elective course in biodesign enables students to expand their abilities as medical device innovators

Educators at the Renaissance School of Medicine (RSOM) at Stony Brook University highlighted the success of their three-year, elective course in biodesign that has enabled students to expand their abilities as innovators to creating potential medical devices for the future.

11 May 2022

New technique uses genetic data that may better predict disease risk in a population

Polygenic risk scores (PRS) are promising tools for forecasting disease risk, but current versions have bias built-in, which can reduce their accuracy in some populations and lead to health disparities.

10 May 2022

Study reveals advance in cell biology may lead to effective cancer therapy technique

According to researchers at Weill Cornell Medicine and the Dana-Farber Cancer Institute, a protein called CDC7, which has long been assumed to play an important role in cell division, may be replaced by another protein called CDK1.

10 May 2022

Study shows how key cause of cancer growth in cell formation may lead to prevention

The University of Warwick’s research gives fresh information on a major cause of cancer growth during cell division (or mitosis), as well as potential treatments for avoiding it.

10 May 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

Discovery could help break the cycle of rapid transmission of TB

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

15 Apr 2022

Gut viruses contribute to human health, but provoke inflammation when perturbed

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

11 Apr 2022

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

11 Apr 2022

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

Medical School News and Research

New computer model helps identify mutations that drive tumor growth

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Researchers devise a new treatment approach to cure aggressive brain tumors

Research may lead to new therapies for metabolic disorders and other diseases

Elective course in biodesign enables students to expand their abilities as medical device innovators

New technique uses genetic data that may better predict disease risk in a population

Study reveals advance in cell biology may lead to effective cancer therapy technique

Study shows how key cause of cancer growth in cell formation may lead to prevention

Study shows how nanotechnology may help for structural research of RNA molecules

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

Discovery could help break the cycle of rapid transmission of TB

Spatial maps offer insights into the battle between melanoma cells and immune cells

Gut viruses contribute to human health, but provoke inflammation when perturbed

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

Certain RNA molecules may serve as markers of cellular stress in different diseases

Researchers discover new type of cell that may play a key role in human lung diseases

RNA targeted by small molecule drugs, likely to create new pathways for disease treatment

Gene mutation influences autism development, study finds

Researchers create an atlas of cell types present in the white adipose tissue of humans, mice

Integrating Software and Solutions to Accelerate Antibody Discovery

CHEMUK 2022: the IBioIC on Industrial Biotechnology

Tackling Food Waste to Protect Our Planet

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