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Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Study demonstrates how DNA-like molecules could have joined to form the origin of life

Nagoya University scientists in Japan have demonstrated how DNA-like molecules could have come together as a precursor to the origins of life.

7 Apr 2021

Unique mini-microscope enables imaging of brain activity in freely moving mice

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days.

6 Apr 2021

Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021

Neurod4 gene found to be the key factor in nerve regeneration after spinal cord injury

Nagoya University researchers have identified a gene that plays a crucial role in regenerating neurons of African clawed frog tadpoles, which has an unusually high capacity for nerve regeneration.

31 Mar 2021

Depletion of stem cells could be a significant factor behind miscarriage

Depletion of a certain type of stem cell in the womb lining during pregnancy could be a significant factor behind miscarriage, according to a study released today in STEM CELLS. The study, by researchers at Warwick Medical School, University of Warwick, Coventry, England, reports on how recurrent pregnancy loss is a result of the loss of decidual precursor cells prior to conception.

26 Mar 2021

Monitoring pollen levels using environmental DNA

In this interview, AZoLifeSciences speaks to Dr. Ben Wheeler about his latest research and how we monitor pollen levels using environmental DNA.

25 Mar 2021

Study shows SARS-CoV-2 antibodies wane at different rates

Researchers from Duke-NUS Medical School, the National Centre for Infectious Diseases (NCID), and the Agency for Science, Technology and Research (A*STAR) Infectious Diseases Labs have discovered that antibodies against SARS-CoV-2 decline at different speeds, and these antibodies last for only a few days in some people but remain for many years in other individuals.

24 Mar 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

Disease-driving B cells play a role in non-alcoholic fatty liver disease

A study by researchers proposes that disease-driving B cells—a kind of white blood cell—have a role in the development of non-alcoholic fatty liver disease.

23 Mar 2021

Study shows beneficial effects of gene therapy can be observed even after several decades

A new study shows that the advantageous effects of gene therapy can be observed several decades after the body clears the transplanted blood stem cells.

18 Mar 2021

New highly sensitive RNA detection method advances in situ transcriptomics

Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.

18 Mar 2021

Medical School News and Research

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

Study demonstrates how DNA-like molecules could have joined to form the origin of life

Unique mini-microscope enables imaging of brain activity in freely moving mice

Supercomputer simulations help uncover the mechanism for HIV replication

Neurod4 gene found to be the key factor in nerve regeneration after spinal cord injury

Depletion of stem cells could be a significant factor behind miscarriage

Monitoring pollen levels using environmental DNA

Study shows SARS-CoV-2 antibodies wane at different rates

Gender difference accounts for major psychiatric disorders

Disease-driving B cells play a role in non-alcoholic fatty liver disease

Study shows beneficial effects of gene therapy can be observed even after several decades

New highly sensitive RNA detection method advances in situ transcriptomics

Collective behavior of bacterial swarms may lead to the emergence of antibiotic resistance

Regenerating bone marrow after chemotherapy

New software tool enables swift analysis of datasets generated from single-cell sequencing

Researchers identify gene variant associated with childhood asthma

Genetic testing technology is extremely unreliable in detecting very rare genetic variants

Gene-based blood test may predict treatment success in people with metastatic melanoma

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

New AI-based method produces new diversity of AAV capsids for optimized gene therapy

Discovering a new genetic mutation in Schizophrenia

Developing a new CRISPR technique

Monitoring pollen levels using environmental DNA

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