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Colombia takes steps to preserve its biodiversity via genomic studies

Researchers from UEA predict that the second-most diverse nation in the world will benefit ecologically, economically, and socially from joining the Earth Biogenome Project.

20 Jan 2022

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

17 Jan 2022

Changes in the activity of gene networks may explain arteriosclerosis risk

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

13 Jan 2022

Researchers map the cellular landscape in diabetic foot ulcers

Diabetic foot ulcerations – open sores or wounds that refuse to heal – are a devastating complication affecting more than 15 percent of people with diabetes and resulting in more than 70,000 lower extremity amputations per year in the United States alone.

11 Jan 2022

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

A folic acid-like drug changes a DNA process within brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

6 Jan 2022

Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

DNA analyses reveals insights into ancestry, social organization of ancient people in the Nile Valley

The first genome-wide ancient human DNA data from Sudan reveals new insights into the ancestry and social organization of people who lived more than 1,000 years ago in the Nile Valley, an important genetic and cultural crossroads.

20 Dec 2021

Researchers use CRISPR-Cas9 to successfully target brown fat

Fat is an essential component of life, however too much fat leads to numerous health issues. Investigating the role played by fat or adipose tissue is significant to get a better understanding of obesity and other problems.

17 Dec 2021

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

New classification method divides breast cancers into 12 distinct biological groups

Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, or their pathology.

9 Dec 2021

Immune cells utilize the body’s fat stores to combat infection, says study

A recent study carried out by the University of East Anglia and Quadram Institute shows how immune cells utilize the body’s fat stores to combat infection.

9 Dec 2021

People previously infected by Chikungunya virus may develop partial immunity to Mayaro virus

A study conducted at the University of São Paulo (USP) in Brazil suggests people previously infected by Chikungunya virus may develop partial immunity to Mayaro virus.

6 Dec 2021

Immune cells in the brain mediate the link between gut microbiome and amyloid beta deposits

New research from the University of Chicago points to microglia, key immune cells in the brain, as a key mediator in the relationship between the gut microbiome and b-amyloid deposits in male mice in a model of Alzheimer's disease.

3 Dec 2021

Anti-idiotype antibodies may explain the long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. Researchers are working to find effective vaccines and therapies, as well as understand the long-term effects of the infection.

26 Nov 2021

New details about Shigella's translocon may help develop effective strategy to block infection

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells.

24 Nov 2021

Research demonstrates how diet affects immunity through the gut microbiome

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

17 Nov 2021

Macrophages found in cardiac tissue protect the failing heart, says study

The Centers for Disease Control and Prevention states that heart failure impacts over six million Americans and is the major reason for death.