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New role for huntingtin protein—neuronal regeneration

A recent study led by the University at Buffalo proposes a novel role for the huntingtin protein (HTT), which leads to Huntington’s disease when mutated.

28 Sep 2022

An inventory of human genetic variation through upgrading the 1000 genomes project resource

The first large-scale WGS project to produce a catalog of human genetic variation was the 1000 Genomes Project (1kGP), which was released as an open-access resource seven years ago.

8 Sep 2022

Study explains the dynamics underlying liver damage

The immune system may attack the liver when fat builds up there. The chemical that triggers these responses has been discovered by Weill Cornell Medicine researchers in a recent study, and this information helps to explain the dynamics of liver damage that can accompany type 2 diabetes and obesity.

23 Aug 2022

BIDMC researchers develop a transformative approach to make more of beige adipose tissues

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

18 Aug 2022

Researchers develop first biohybrid model of human ventricles with helically aligned beating cardiac cells

Heart disease -; the leading cause of death in the U.S. -; is so deadly in part because the heart, unlike other organs, cannot repair itself after injury.

11 Jul 2022

New study shows mother’s gut microbes may help in the healthy growth of the placenta

According to a recent study from the University of East Anglia, a mother’s gut microbes can aid in the formation of the placenta and the healthy development of the baby.

1 Jul 2022

New computer model helps identify mutations that drive tumor growth

Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

22 Jun 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

27 May 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Research may lead to new therapies for metabolic disorders and other diseases

Researchers at UT Southwestern have uncovered a molecular path that allows cells to detect when their lipid supplies are running low, triggering a flurry of activity that avoids starvation.

23 May 2022

Elective course in biodesign enables students to expand their abilities as medical device innovators

Educators at the Renaissance School of Medicine (RSOM) at Stony Brook University highlighted the success of their three-year, elective course in biodesign that has enabled students to expand their abilities as innovators to creating potential medical devices for the future.

11 May 2022

New technique uses genetic data that may better predict disease risk in a population

Polygenic risk scores (PRS) are promising tools for forecasting disease risk, but current versions have bias built-in, which can reduce their accuracy in some populations and lead to health disparities.

10 May 2022

Study reveals advance in cell biology may lead to effective cancer therapy technique

According to researchers at Weill Cornell Medicine and the Dana-Farber Cancer Institute, a protein called CDC7, which has long been assumed to play an important role in cell division, may be replaced by another protein called CDK1.

10 May 2022

Study shows how key cause of cancer growth in cell formation may lead to prevention

The University of Warwick’s research gives fresh information on a major cause of cancer growth during cell division (or mitosis), as well as potential treatments for avoiding it.

10 May 2022

Study shows how nanotechnology may help for structural research of RNA molecules

Humans live in a world created and managed by RNA—the genetic molecule DNA’s equally important sibling.

3 May 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

Discovery could help break the cycle of rapid transmission of TB

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

15 Apr 2022

Gut viruses contribute to human health, but provoke inflammation when perturbed

Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine?

11 Apr 2022

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

11 Apr 2022

Medical School News and Research

New role for huntingtin protein—neuronal regeneration

An inventory of human genetic variation through upgrading the 1000 genomes project resource

Study explains the dynamics underlying liver damage

BIDMC researchers develop a transformative approach to make more of beige adipose tissues

Researchers develop first biohybrid model of human ventricles with helically aligned beating cardiac cells

New study shows mother’s gut microbes may help in the healthy growth of the placenta

New computer model helps identify mutations that drive tumor growth

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Researchers devise a new treatment approach to cure aggressive brain tumors

Research may lead to new therapies for metabolic disorders and other diseases

Elective course in biodesign enables students to expand their abilities as medical device innovators

New technique uses genetic data that may better predict disease risk in a population

Study reveals advance in cell biology may lead to effective cancer therapy technique

Study shows how key cause of cancer growth in cell formation may lead to prevention

Study shows how nanotechnology may help for structural research of RNA molecules

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

Discovery could help break the cycle of rapid transmission of TB

Spatial maps offer insights into the battle between melanoma cells and immune cells

Gut viruses contribute to human health, but provoke inflammation when perturbed

Microcolonies in the GI tract comprise an important niche for cell-cell signaling and plasmid transfer

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

Turning to Sustainable Science for a Healthier Tomorrow

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