Metabolites News and Research

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Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021

Study reveals molecular mechanisms involved in the maintenance of naïve embryonic stem cells

Researchers have explained mechanisms that play a role in maintaining the embryonic stem cells in the most optimized state for use in regenerative medicine.

26 Mar 2021

New technique can measure thousands of proteins in a few minutes

Researchers from Charité - Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes.

26 Mar 2021

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

A multi-institutional collaboration has revealed that α-solanine, a toxic compound found in potato plants, is a divergent of the bitter-tasting α-tomatine, which is found in tomato plants.

26 Mar 2021

Scientists identify new biomarkers in the blood of patients with malignant melanoma

A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant melanoma.

26 Mar 2021

Study reveals a promising material to control root-knot nematodes

Root-knot nematodes are known to infect a wide variety of plants, including many agriculturally significant species, as well as a variety of ornamentals and vegetables.

23 Mar 2021

Volatile signal in plants activates defense and inhibits growth processes

An international research team has performed a new study that revealed that Arabidopsis thaliana plants create beta-cyclocitral when attacked by herbivores.

10 Mar 2021

New automated workflow to identify genetic basis of microbial growth inhibition

Researchers at the Earlham Institute (EI) have created a new automated workflow using liquid handling robots to identify the genetic basis to prevent plant pathogens, which can be used on a much larger and rapid scale than current methods.

5 Mar 2021

Scientists map previously unknown metabolic pathways to produce memory T cell

Immunologists have plotted a previously unfamiliar biological pathway through which the immune system produces T cells that destroy viruses.

26 Feb 2021

Study reveals link between group of metabolites in blood and satiety perception

Results of the European study SATIN (SATiety INnovation) reveal a relation between certain metabolites in the blood and the satiety perceived after consuming food.

23 Feb 2021

Study reveals distinct gut microbiome signature associated with healthy aging, longevity

The gut microbiome is considered an essential part of the body, but its significance in the human aging process is still vague.

22 Feb 2021

Study may lead to alternative treatment for potentially addictive opioid pain killers

When two naturally occurring lipids are altered using a process called epoxidation, they are transformed into powerful agents that target numerous cannabinoid receptors in neurons, disrupting pathways that promote inflammation and pain.

11 Feb 2021

New protein quality control system could enhance full-length translation in bacteria

Professor Sang Woo’s research group has designed a synthetic protein quality control system to improve the full-length translation in bacteria.

9 Feb 2021

Fecal microbiota transplant helps cancer patients respond to immunotherapy

For patients with cancers that do not respond to immunotherapy drugs, adjusting the composition of microorganisms in the intestines--known as the gut microbiome--through the use of a stool, or fecal, transplants may help some of these individuals respond to the immunotherapy drugs, a new study suggests.

From National Cancer Institute (NCI) 5 Feb 2021

Researchers gain a deep insight into the evolutionary history of bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients. These include receptors for bitter compounds, which first evolved during evolution in bony fishes such as the coelacanth.

3 Feb 2021

Changes in mitochondria could cause health problems in Space

News-Medical speaks to Dr. Beheshti from NASA about his latest research that investigated whether changes in mitochondria could cause health problems in Space.

From NASA 29 Jan 2021

Juicing technique can influence phytochemical content, antioxidant activity of vegetable juices

With the New Year, many people are making resolutions to eat healthier, by eating more vegetables, for example. But those who don't like the taste or texture of some vegetables might prefer to drink them in a home-squeezed juice.

28 Jan 2021

Fecal microbiome differs in healthy and food-allergic twins

A new study out of the University of Chicago and Stanford University on pairs of twins with and without food allergies has identified potential microbial players in this condition. The results were published on Jan. 19 in the Journal of Clinical Investigation.

20 Jan 2021

Study explains operating mode of mitochondrial sorting and assembly machinery

Mitochondria are vital for the human body as cellular powerhouses: They possess more than 1,000 different proteins, required for many central metabolic pathways. Disfunction of these leads to severe diseases, especially of the nervous system and the heart.

18 Jan 2021

UT Southwestern biochemist is honoured for breakthrough metabolic research

UT Southwestern Biochemist Benjamin Tu, Ph.D., is the recipient of the 2021 Edith and Peter O'Donnell Award in Science from TAMEST (The Academy of Medicine, Engineering and Science of Texas). He was chosen for his pioneering research on cellular roles of small molecule metabolites that may have relevance for cancer treatments and other diseases.

15 Jan 2021

Metabolites News and Research

Supercomputer simulations help uncover the mechanism for HIV replication

Study reveals molecular mechanisms involved in the maintenance of naïve embryonic stem cells

New technique can measure thousands of proteins in a few minutes

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

Scientists identify new biomarkers in the blood of patients with malignant melanoma

Study reveals a promising material to control root-knot nematodes

Volatile signal in plants activates defense and inhibits growth processes

New automated workflow to identify genetic basis of microbial growth inhibition

Scientists map previously unknown metabolic pathways to produce memory T cell

Study reveals link between group of metabolites in blood and satiety perception

Study reveals distinct gut microbiome signature associated with healthy aging, longevity

Study may lead to alternative treatment for potentially addictive opioid pain killers

New protein quality control system could enhance full-length translation in bacteria

Fecal microbiota transplant helps cancer patients respond to immunotherapy

Researchers gain a deep insight into the evolutionary history of bitter receptors

Changes in mitochondria could cause health problems in Space

Juicing technique can influence phytochemical content, antioxidant activity of vegetable juices

Fecal microbiome differs in healthy and food-allergic twins

Study explains operating mode of mitochondrial sorting and assembly machinery

UT Southwestern biochemist is honoured for breakthrough metabolic research

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