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Expanding the Fruit Fly Tree of Life with New Genomic Data

A multitude of new genomic sequence data fills major gaps in the fruit fly tree of life, Bernard Kim from Stanford University, US, and colleagues report in the open-access journal PLOS Biology, publishing July 18th.

19 Jul 2024

Enhanced Maize Transformation Efficiency Through Ternary Vectors and Morphogenic Regulators

Maize is one of the classical model organisms for genetic research. However, the low transformation frequency remains an important bottleneck for many gene-editing applications.

25 Jun 2024

Study Reveals Allele-Specific DNA Methylation in Hybrid Poplar Regeneration

Understanding plant regeneration at the molecular level is pivotal for advancements in genetic transformation and genome editing.

27 May 2024

Exploring the Evolution of Mitosis: Lessons from Close Relatives of Fungi and Animals

Cell division is one of the most fundamental processes of life. From bacteria to blue whales, every living being on Earth relies on cell division for growth, reproduction, and species survival.

23 May 2024

Unlocking Brown Fat's Potential: Study Reveals Key Protein in Obesity Regulation

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

30 Apr 2024

Study Provides Insights Into Molecular Mechanisms Underlying Healthy Aging in Drosophila

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut."

28 Feb 2024

Study Suggests a Link Between DNA Methylation Disorder and Epigenetic Clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation."

7 Feb 2024

Universal Networking Principles Wire Up Different Brains

A new study by physicists and neuroscientists from the University of Chicago, Harvard and Yale describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.

18 Jan 2024

Sirtuin 6 Boosts DNA Repair in Aging Cartilage Cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes."

20 Dec 2023

Decoding Zebrafish Development: A Comprehensive Gene Expression Atlas

Scientists from the National Institutes of Health have released a comprehensive guide to the development of zebrafish, outlining the gene expression patterns activated in almost every cell type during the initial five days of growth.

19 Dec 2023

Omicron's Cellular Senescence May Explain Cytokine Storms and Long-COVID

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence."

18 Dec 2023

Arabidopsis thaliana’s Pioneering Role in Complete Genome Sequencing

Arabidopsis thaliana, a globally cultivated species for genetic research, achieved the milestone of being the first plant to undergo complete genome sequencing.

18 Dec 2023

Study Highlights Cellular and Molecular Characteristics of Senescent Ocular Surface Cells

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 18, entitled, "Gene expression signatures of human senescent corneal and conjunctival epithelial cells."

4 Oct 2023

New Discovery Leads to Underlying Factors to Gene Size Variations

The present understanding of genomic stability and variability is mostly based on a few model species, leaving the scope and generality of these discoveries uncertain.

9 Aug 2023

Malaria Parasite’s Meiosis Could Hold the Key to New Treatments

Researchers from the Universities of Leicester and Nottingham have been awarded nearly £600,000 to investigate how sexual development and gene shuffling inside the malaria parasite can help regulate malaria transmission.

7 Aug 2023

New Insight Into the Physiology of NO-Reducing Microorganisms

Nitric oxide (NO) is a central molecule in the global cycling of nitrogen, and also toxic. Little is known about if and how microbes can use NO as a substrate for growth.

11 Jul 2023

Novel Peptide may be Key to Understanding Skin Aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "A novel peptide 'T14' reflects age and photo-aging in human skin."

6 Jul 2023

New Approach to Revolutionize Synthetic Biology

For the first time, scientists at the Lawrence Berkeley National Laboratory of the Department of Energy (Berkeley Lab) have created a genome-scale method to map the regulatory role of transcription factors, proteins that are essential for controlling gene expression, and a plant’s physiological features.

22 Jun 2023

Study Provides Evidence for Involvement of p53/p16/RB-E2F-DREAM Repressional Targets in Cellular Senescence

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex."

14 Jun 2023

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

2 Jun 2023