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New research on mitochondrial function can play significant part in serious disease

Disorders of the cells' energy supply can cause a number of serious diseases, but also seem to be connected to aging.

22 Feb 2021

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

19 Feb 2021

Using soil bacteria for antibiotic production

In this interview, AZoLifeSciences speaks to Dr. Christophe Corre about his latest research that investigated soil bacteria and how it could be used to produce antibiotics.

19 Feb 2021

Study reveals novel antibody binding implicated in liver and breast cancer

In the field of structural biology, certain molecules are so uncommon that they can only be captured with a special set of tools.

18 Feb 2021

New hydrogel shrinks tumors in melanoma mice model

Recently, messenger RNA, also called mRNA, vaccines, to combat the COVID-19 infection have made headlines worldwide, but researchers have already been experimenting with mRNA vaccines to prevent or cure other illnesses, including certain types of cancer.

18 Feb 2021

Study reveals the structure of heat shock proteins that could treat Huntington's disease

In Huntington's disease, a faulty protein aggregates in brain cells and eventually kills them. Such protein aggregates could, in principle, be prevented with a heat shock protein.

15 Feb 2021

Animal model yields important insights into T cell exhaustion

T lymphocytes, or T cells, are an important component of our immune system. They can recognize foreign proteins, so-called antigens, as peptide fragments - for instance, those derived from viruses or cancer cells.

15 Feb 2021

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.

15 Feb 2021

Study reveals key process by which plants switch between different stress responses

To design effective strategies that protect significant agricultural crops from climate change, it is important to understand how plants react to stressful environmental conditions.

15 Feb 2021

Study reveals a new role of SRC-3 protein in various cancers

New research has revealed a new role of the steroid receptor coactivator 3, also called SRC-3/NCOA3.

15 Feb 2021

Tiny population of neurons may play a significant role in depression

A tiny population of neurons known to be important to appetite appear to also have a significant role in depression that results from unpredictable, chronic stress, scientists say.

12 Feb 2021

An outlook on latest trends in peptide drug discovery and development

Currently, there are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of diseases such as diabetes, cancer, hormone disorders, HIV infection, and multiple sclerosis.

11 Feb 2021

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer. Moreover, doctors cannot accurately predict which of their patients will respond.

11 Feb 2021

Manufacturers of fragrance products are pivoting to a new way to source ingredients

In the face of a changing climate and crop diseases, manufacturers of products containing natural flavors and fragrances are pivoting to a new way to source ingredients.

11 Feb 2021

Researchers program genome tool to target specific histone proteins

If finding a needle in a haystack is hard enough, then one should try finding a particular molecule on the needle.

11 Feb 2021

New simplified approach for producing pharmaceutical substances

Tetrahydroisoquinolines (THIQ) are organic compounds, whose structure includes a benzene ring merged with a nitrogen-containing cycle.

11 Feb 2021

Light-activated protein can be used to study single synapses of neurons

Neurons are the primary cells of the nervous system, and the signals that are transmitted between them are responsible for all our actions and our cognitive ability.

10 Feb 2021

Study uncovers how cells actively seek information to make better collective decisions

Cells, like humans, cast votes to make decisions as a group. But how do they know what to vote for? Researchers at the Francis Crick Institute and King's College London have uncovered how cells actively seek information in order to make faster and better collective decisions to coordinate the growth of new blood vessels. This provides a new basis for understanding intelligence in cells.

9 Feb 2021

$1.8 million NIH grant supports research on extracellular vesicles

Scientists have known for decades that our cells constantly shed tiny pieces known as extracellular vesicles (EVs), but until relatively recently they believed that this process was merely a way for cells to rid themselves of material that was no longer needed.

8 Feb 2021

Vaccine based on virus-like particle could generate antibodies to prevent malaria

An inexpensive, long-lasting and easy-to-administer vaccine against malaria could be a game-changer for millions of people living in countries where the mosquito-borne disease is endemic.

5 Feb 2021

Molecule News and Research

New research on mitochondrial function can play significant part in serious disease

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Using soil bacteria for antibiotic production

Study reveals novel antibody binding implicated in liver and breast cancer

New hydrogel shrinks tumors in melanoma mice model

Study reveals the structure of heat shock proteins that could treat Huntington's disease

Animal model yields important insights into T cell exhaustion

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Study reveals key process by which plants switch between different stress responses

Study reveals a new role of SRC-3 protein in various cancers

Tiny population of neurons may play a significant role in depression

An outlook on latest trends in peptide drug discovery and development

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

Manufacturers of fragrance products are pivoting to a new way to source ingredients

Researchers program genome tool to target specific histone proteins

New simplified approach for producing pharmaceutical substances

Light-activated protein can be used to study single synapses of neurons

Study uncovers how cells actively seek information to make better collective decisions

$1.8 million NIH grant supports research on extracellular vesicles

Vaccine based on virus-like particle could generate antibodies to prevent malaria

Two new Alzheimer’s genes discovered

How is climate change affecting the allergy season?

Using soil bacteria for antibiotic production

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