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Scientists Uncover Key Plant Metabolite to Block Biofilm Development

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

13 Jan 2025

Research Shows How Sleep Clears Brain Waste

A good night's sleep does more than just help you feel rested-it might literally clear your mind. A new study published January 8 in the Cell Press journal Cell shows how deep sleep may wash away waste buildup in the brain during waking hours, an essential process for maintaining brain health.

10 Jan 2025

Scientists Uncover Circuit Controlling Neuron Migration in Brain Development

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

10 Jan 2025

Illuminating RNA Function with Innovative Bioluminescent Probes

The molecule that reads the genetic data contained in DNA is called RNA. Researchers at the University of California, Irvine have found a method to tag RNA with a glowing bioluminescent molecule, which enables them to track RNA in real time as it travels throughout the body.

10 Jan 2025

RNAConnect Debuts The New UltraMarathonRT® RT-qPCR Kit to Improve Reliability Of Gene Expression Analysis

RNAConnect, developer of enzymatic tools for visualizing and manipulating RNA, today announced the release of the UltraMarathonRT® Two-Step RT-qPCR Kit, a next-generation tool for RNA researchers conducting gene expression analysis.

9 Jan 2025

Breakthrough in Nanopore Technology Could Transform Disease Detection

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

3 Jan 2025

New Study Reveals DNA’s Role in Stabilizing Cellular Structures

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life: DNA and the element magnesium.

26 Dec 2024

New Method Improves Quantification of Endocytosis in Living Cells

Living cells and tissues show a high capacity to absorb various chemical compounds from the surrounding environment.

23 Dec 2024

New Synthetic Biology Tool Improves Genetic Circuit Integration and Functionality

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

23 Dec 2024

High-Resolution Technique Maps Ribosome Elongation Cycle

At one time or another, most of us have played with a flipbook, using our thumbs to rapidly flip a series of pictures to create an illusion of movement.

20 Dec 2024

A Novel Method for Synthesizing Piperidines for Modern Medicine

A team of chemists from Scripps Research and Rice University has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study, published in Science, combines biocatalytic carbon-hydrogen oxidation and radical cross-coupling, offering a streamlined and cost-effective approach to create complex, three-dimensional molecules.

19 Dec 2024

Neural Stem Cells Found to Rejuvenate the Aging Brain

Much like plants in a thriving forest, certain cells in the brain create a nurturing environment, enhancing the health and resilience of their neighbors, while others promote stress and damage, akin to a noxious weed in an ecosystem.

19 Dec 2024

Scientists Mimic Fungal Process to Create Novel Medicines

Since the unintentional 1928 discovery of penicillin by Alexander Fleming, fungi have been a treasure trove of medicinal compounds for almost a century.

19 Dec 2024

Researchers Map Influenza Virus RNA Protective Coat at Atomic Level

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of eight RNA molecules.

17 Dec 2024

Advancing Sequential DNA Computing for Programmable Devices

DNA stores the instructions for life and, along with enzymes and other molecules, computes everything from hair color to risk of developing diseases.

13 Dec 2024

Programmable G-protein-coupled receptors redefine therapeutic applications.

This study demonstrates the development of PAGERs (programmable antigen-gated engineered receptors), combining antigen specificity, modular adaptability, and drug-controlled activation, with potential applications in synthetic biology, therapeutics, and neuroscience.

12 Dec 2024

Ribosomal Fingerprints: A Novel Approach to Early Cancer Detection

Different types of cancer have unique molecular 'fingerprints' which are detectable in early stages of the disease and can be picked up with near-perfect accuracy by small, portable scanners in just a few hours, according to a study published today in the journal Molecular Cell.

11 Dec 2024