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Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

From UC San Diego 20 Aug 2021

New method can efficiently convert plant matter into high-value bioproducts

A team of scientists at the University of Illinois Urbana-Champaign developed a bioprocess using engineered yeast that completely and efficiently converted plant matter consisting of acetate and xylose into high-value bioproducts.

18 Aug 2021

Study assesses the effectiveness of T-cell immune response to different SARS-CoV-2 variants

New mutations of the SARS-CoV-2 virus have been emerging continuously, enabling a more potent spread of the virus and allowing it to evade antibodies.

16 Aug 2021

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

The single-stranded genetic material RNA is best known for guiding the assembly of proteins in our cells and carrying the genetic code for viruses like SARS-CoV-2 and HIV.

16 Aug 2021

New molecule can effectively deplete cancer-protecting cells inside tumors

A new study has discovered a two-arm molecule that can effectively deplete cancer-protecting cells within tumors.

16 Aug 2021

Study shows plants reuse secondary metabolites in primary metabolism

Plant researchers identified that plants are capable of reusing specialized metabolic products and break them down to recover nutrients.

12 Aug 2021

Dileucine turns up muscle-building process more than leucine, study finds

In a randomized control study of 10 healthy young men, researchers compared how consuming the single amino acid leucine or its two-molecule equivalent, dileucine, influenced muscle-building and breakdown.

10 Aug 2021

Scientists show how lab-grown beating heart cells are vulnerable to SARS-CoV-2 infection

Cambridge scientists have grown beating heart cells in the lab and shown how they are vulnerable to SARS-CoV-2 infection. In a study published in Communications Biology, they used this system to show that an experimental peptide drug called DX600 can prevent the virus entering the heart cells.

6 Aug 2021

Experimental small molecule could help treat Parkinson’s disease in future

A new study has demonstrated the removal of damaged mitochondria from the brain cells of mice treated with a small molecule compound for Parkinson’s disease.

5 Aug 2021

Study reveals melanoma is associated with a chemical conversion in DNA

According to recent research, the mutations giving rise to melanoma are the outcome of a chemical conversion in DNA triggered by sunlight.

3 Aug 2021

Study: Biomarker can predict response to immunotherapies in breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

28 Jul 2021

Yeast study reveals a protein involved in gross chromosomal rearrangements

Gross chromosomal rearrangements--where portions of the genome become moved, deleted, or inverted--can lead to cell death and diseases such as cancer in complex multicellular organisms.

23 Jul 2021

Already characterized active substances exhibit unexpected effects

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

New study uncovers how enterococcal cytolysins affect cells

Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers have uncovered how they do so.

22 Jul 2021

Researchers discover nucleotide sequences characteristic of microRNA isoforms

$Microcrystal electron diffraction could help obtain potential pharmaceutical structures$

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

In the process of drug development, solving structures of potential therapeutics with X-ray diffraction (XRD) has been a presumed, critical step so far.

16 Jul 2021

Molecule News and Research

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

New method can efficiently convert plant matter into high-value bioproducts

Study assesses the effectiveness of T-cell immune response to different SARS-CoV-2 variants

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

New molecule can effectively deplete cancer-protecting cells inside tumors

Study shows plants reuse secondary metabolites in primary metabolism

Dileucine turns up muscle-building process more than leucine, study finds

Scientists show how lab-grown beating heart cells are vulnerable to SARS-CoV-2 infection

Experimental small molecule could help treat Parkinson’s disease in future

Study reveals melanoma is associated with a chemical conversion in DNA

Study: Biomarker can predict response to immunotherapies in breast cancer patients

Yeast study reveals a protein involved in gross chromosomal rearrangements

Already characterized active substances exhibit unexpected effects

New study uncovers how enterococcal cytolysins affect cells

Researchers discover nucleotide sequences characteristic of microRNA isoforms

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Study unravels gene expression control mechanism with immunity and cancer implications

New study could prevent T cell exhaustion in the immune system’s fight against cancer

Study shows how single cells take up fatty acids, offering new insights into cancer biology

Microcrystal electron diffraction could help obtain potential pharmaceutical structures

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