Mutation News and Research

RSS

Choosing alternate pathways of DNA repair to limit harmful chromosomal rearrangements

Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism.

From Osaka University 30 Apr 2020

Study finds utrophin-based therapy could be used to treat Duchenne muscular dystrophy

If an actor is not in a position to perform in the theatre, an understudy—preferably one with some practice in the role—can take that role on stage.

27 Apr 2020

Understanding evolution of early life may be trickier than previously thought

Biologists have long hoped to understand the nature of the earliest living organisms on Earth. If they could, they might then be able to say something about how, when, and where life arose on Earth, and perhaps by extension, whether life is common in the Universe.

23 Apr 2020

Researchers develop new molecular workflow to study single-cell genomics of diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

23 Apr 2020

New study could lead to effective immunotherapy treatments for cancer patients

According to a study recently published in the eLife journal, researchers have devised a new method to chart the molecules present on tumor cells that indicate their presence to the immune system.

22 Apr 2020

Advanced simulations show how to improve efficiency of gene therapy

Diseases with a genetic cause could, in theory, be treated by supplying a correct version of the faulty gene.

20 Apr 2020

New algorithm predicts the evolution of genetic mutations in species

David McCandlish and Juannan Zhou, both quantitative biologists at the Cold Spring Harbor Laboratory, have designed a new algorithm that has predictive power, providing researchers the ability to observe the way particular genetic mutations combine to make crucial proteins change over the duration of a species’ evolution.

16 Apr 2020

Genetic architecture of life span is context dependent, study finds

Scientists believe about 25 percent of the differences in human life span is determined by genetics -- with the rest determined by environmental and lifestyle factors. But they don't yet know all the genes that contribute to a long life.

15 Apr 2020

Combined effect of rare mutations has negative impact on health and longevity

In a study published recently in the eLife journal, researchers have reported that the combined effects of rare and damaging mutations that occur at birth itself have adverse effects on health span and longevity.

13 Apr 2020

Study examines molecular causes of spondylocostal dysostosis

Researchers from EMBL Barcelona’s Ebisuya group collaborated with colleagues from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, to investigate oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro.

7 Apr 2020

UMSOM researchers uncover mechanism to explain role of genetic mutations in kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

6 Apr 2020

Scientists Discover Gene That Increases Risk Of Alzheimer's Disease

Researchers from UBC and the Central South University (CSU) in China have for the first time identified a gene that increases the risk of Alzheimer's disease.

2 Apr 2020

Stem cell strategy can help improve the effectiveness of cardiac repair

Human stem cells have been typically perceived as one of the potential cell sources for cardiac regeneration treatment. However, the substandard performance following transplantation into the failing hearts has limited their applications in clinical use.

30 Mar 2020

Mutation News and Research

Choosing alternate pathways of DNA repair to limit harmful chromosomal rearrangements

Study finds utrophin-based therapy could be used to treat Duchenne muscular dystrophy

Understanding evolution of early life may be trickier than previously thought

Researchers develop new molecular workflow to study single-cell genomics of diseases

New study could lead to effective immunotherapy treatments for cancer patients

Advanced simulations show how to improve efficiency of gene therapy

New algorithm predicts the evolution of genetic mutations in species

Genetic architecture of life span is context dependent, study finds

Combined effect of rare mutations has negative impact on health and longevity

Study examines molecular causes of spondylocostal dysostosis

UMSOM researchers uncover mechanism to explain role of genetic mutations in kidney disease

Scientists Discover Gene That Increases Risk Of Alzheimer's Disease

Stem cell strategy can help improve the effectiveness of cardiac repair

Large mutations may explain diverse outcomes from autism genes

Researchers capture occurrence of bursts of diversity in microbiota in real time

Study finds impact of specific gene on neurodevelopment, causing ASD and macrocephaly

New canine study can benefit diagnostics and treatment of retinitis pigmentosa

Researchers successfully crystallize and map novel conformation of LeuT transporter

New method has revealed how cells communicate

Distinct loss-of-function variants cause shared clinical features in neuronal development disorders

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Latest in Genomics