Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Scientists Pioneer mRNA Approach to Target Alzheimer's Protein

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

29 Mar 2024

Nanoparticle-Based Therapy Shows Promise in Eradicating Tumors

A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types.

28 Mar 2024

Scientists Create "Immunologically Silent" DNA Vaccine for Potent Virus Defense

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

31 Jan 2024

Tailored Nanoparticles Deliver siRNA to Reduce Neuroinflammation in Alzheimer's Disease Models

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells.

11 Dec 2023

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

31 Oct 2023

New Synthetic Catalyst Breaks Down Cellulose: Study

Yan Zhao gestured toward the trees outside his campus window on a rainy afternoon.

22 Aug 2023

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

Berkeley Lab and Genentech Team Up to Develop Next-Generation Drug Delivery System

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

18 Jul 2023

Gene Recognition of CRISPR-Cas Visualized With New Method

A novel technique has been devised by researchers from the University of Leipzig and the University of Vilnius in Lithuania to monitor the smallest twists and torques of molecules in milliseconds.

13 Jul 2023

The Future of Nanobiotechnology: Ethical Considerations

Prosthetics moved by thoughts. Targeted treatments for aggressive brain cancer. Soldiers with enhanced vision or bionic ears.

13 Jul 2023

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

29 Jun 2023

A New Method to Escape from Metastability

Prof. Haojun Liang of the Chinese Academy of Sciences’ (CAS) University of Science and Technology of China (USTC) suggested a new way to escape from metastability for self-assembly in a far-from-equilibrium system. The study was published in the journal PNAS.

12 Jun 2023

Researchers Develop a System to Deliver Antioxidants to the Mitochondria

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

11 May 2023

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.

4 Apr 2023

Metal labeling strategy for single-cell multiplexing with mass cytometry

Recently, a new metal labeling strategy has been suggested by researchers from the Suzhou Institute of Biomedical Engineering and Technology (SIBET) of the Chinese Academy of Sciences (CAS) to boost mass cytometry’s sensitivity and increase the number of MC detection channels.

31 Mar 2023

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

31 Mar 2023

New nanoparticles can perform gene editing in the lungs, paving the way for inhalable therapies

Nanoparticles can be used to deliver messenger RNA encoding proteins to the lungs, results of a new study carried out at MIT and the University of Massachusetts Medical School show.

From Massachusetts Institute of Technology (MIT) 30 Mar 2023

LDL-mediated nanoparticle drug delivery could potentially circumvent high-grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

8 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023