In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.
Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells.
Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.
Yan Zhao gestured toward the trees outside his campus window on a rainy afternoon.
Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.
In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.
Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.
A novel technique has been devised by researchers from the University of Leipzig and the University of Vilnius in Lithuania to monitor the smallest twists and torques of molecules in milliseconds.
Prosthetics moved by thoughts. Targeted treatments for aggressive brain cancer. Soldiers with enhanced vision or bionic ears.
Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.
Prof. Haojun Liang of the Chinese Academy of Sciences’ (CAS) University of Science and Technology of China (USTC) suggested a new way to escape from metastability for self-assembly in a far-from-equilibrium system. The study was published in the journal PNAS.
A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.
Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.
Recently, a new metal labeling strategy has been suggested by researchers from the Suzhou Institute of Biomedical Engineering and Technology (SIBET) of the Chinese Academy of Sciences (CAS) to boost mass cytometry’s sensitivity and increase the number of MC detection channels.
Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.
Nanoparticles can be used to deliver messenger RNA encoding proteins to the lungs, results of a new study carried out at MIT and the University of Massachusetts Medical School show.
New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.
Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.
Using a specialized MRI sensor, MIT researchers have shown that they can detect light deep within tissues such as the brain.
Neurons are the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles, and for transforming and relaying the electrical signals at every step in between.