Neural Stem Cells News and Research

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RNA Modification Offers Hope for Treating Neurological Diseases

The research team led by Yongchao C. Ma, Ph.D., at the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, uncovered a fundamental biological mechanism that holds promise for the development of novel treatments for neurological disorders like spinal muscular atrophy (SMA) and autism, as well as various types of cancer.

5 Apr 2024

Autofluorescence Reveals Clues to Stem Cell Dormancy

With the help of a tool created at the University of Wisconsin–Madison, researchers can better study the various states of stem cells in the nervous system by utilizing the light naturally emitted by biological specimens.

28 Mar 2024

Uncovering New Insights Into Primate Brain Evolution

In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.

27 Oct 2023

Lactate Signaling Found to Be Critical for Neuronal Differentiation

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

25 Jul 2023

Glycosylation Enzyme Regulates the Formation of Neurons and Astrocytes From Neural Stem Cells

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

17 May 2023

Analyzing the Cell Division in Stem Cells

What appears to be a simple task for a cell—splitting in two—is indeed a complex series of engineering puzzles. To produce two working cells, a splitting cell has to maneuver its interiors in such a way that the appropriate components will end up in each cell.

3 May 2023

Researchers find methods to awaken and revive neural stem cells

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. A team led by scientists from the Universities of Geneva (UNIGE) and Lausanne (UNIL) has discovered the importance of cell metabolism in this process and identified how to wake up these neural stem cells and reactivate them. Biologists succeeded in increasing the number of new neurons in the brain of adult and even elderly mice. These results, promising for the treatment of neurodegenerative diseases, are to be discovered in the journal Science Advances.

2 Mar 2023

New molecular understanding of how head injury may contribute to glioma risk

Researchers from the UCL Cancer Institute have provided important molecular understanding of how injury may contribute to the development of a relatively rare but often aggressive form of brain tumor called a glioma.

27 Feb 2023

Synthetic hydrogels provide an effective scaffold for brain tissue growth

Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.

24 Feb 2023

Scientists receive $2.5 million NIH grant to define the role of lipid droplets in muscle stem cell function

A team of Purdue University scientists led by Shihuan Kuang has received a $2.5 million grant from the National Institutes of Health to define the role of lipid droplets in muscle stem cell function, a study with implications in both humans and livestock.

24 Feb 2023

Involvement of the piRNA pathway in brain plasticity and successful aging

The Neurobiology of miRNA team, headed by Davide De Pietri Tonelli of the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology), established a link between a family of small RNA molecules known as piRNAs and brain inflammation.

16 Dec 2022

UC San Diego Alpha Clinic awarded $8 million to bring new stem cell-based therapies to patients

Stem cells show particular promise in treating diseases for which few other effective treatments exist.

25 Nov 2022

New guidelines to generate high-quality, well-structured organoids

Researchers have opened a new avenue for investigations of neurological development, disease, and therapies that cannot be undertaken in living people by employing stem cells to grow small brain-like structures in the lab.

30 Sep 2022

Spatial transcriptomic data highlights the features of the axolotl brain

The first spatiotemporal cellular atlas of axolotl (Ambystoma mexicanum) brain growth and regeneration, created by a multi-institute research team under the direction of BGI-Research, reveals how brain damage may recover itself.

8 Sep 2022

Researchers discover how the protein content of centrosomes may vary on cell type

The centrosome is the organelle that organizes the cytoskeleton during cell division, which is an important role in species ranging from yeast to humans. Due to its broad functions, scientists previously considered that the centrosome was quite similar in all cells.

17 Jun 2022

Scientists identify factors that regulate the development of brain cells in a specific order

Researchers have identified the complete series of 10 factors that regulate the development of brain cell types in the visual system of fruit flies-; including in what order these neurons develop.

From New York University (NYU) 7 Apr 2022

Understanding how cleaning up bad mitochondria affects stem cell division

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

1 Apr 2022

YME1L protein responsible for balancing the conversion of brain's neural stem cells

Researchers at the University of Cologne have discovered that the protein YME1L regulates the production of new nerve cells and the maintenance of neural stem cells in the adult brain.

16 Feb 2022

Stringent lineage tracing crucial for studies of nerve cell regeneration

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

30 Sep 2021

Novel protein interactions aid in the recovery process of brain damage

Patients suffering from brain damage largely depend on rehabilitation therapy for recovery, because no other effective treatment options are available.

21 Jun 2021