Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.
Stem cells show particular promise in treating diseases for which few other effective treatments exist.
Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.
AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.
Stem cells are a type of cell that can be configured to transform into almost any sort of cell in the body. They are presently used in research on organ development as well as in the initial phases of embryo development.
Aging and age-related diseases present a complex challenge to biomedical researchers.
According to the latest research, medical and life science scientists will benefit from the most detailed atlas of zebrafish genetic data available.
A single gene that was previously discovered to be the main factor in a rare disease associated with epilepsy, autism, and developmental delay has been named as a key player in the development of healthy neurons.
A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery.
Mermaid Bio GmbH of Munich, Germany, and WEHI of Melbourne, Australia, recently announced cooperation to identify and develop a unique class of therapeutic candidates that modify misbehaving proteins inside cells that can cause a variety of diseases.
Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.
The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.
When a condition is connected to a genetic mutation, it is generally negative news.
Scientists at Rejuveron Vascular Therapeutics AG, a company specializing in the development of therapies to tackle neurodegeneration, are using INTEGRA’s VIAFLO 384 handheld electronic pipette to accelerate their research.
As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins.
Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.
Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.
Scripps Research scientists have discovered evidence that a chemical present in rosemary might be a two-pronged weapon against SARS-CoV-2.
Scientists discovered hundreds of proteins that are constantly transferred throughout the healthy brain in small membrane-enclosed sacs.
A thread-like highway, called microtubule tracks, allows motor proteins to transport cargo inside neurons.
A group of researchers recently unearthed vital information on how gene expression is orchestrated.