Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.
Neurons cannot simulate their DNA and hence they work continuously to repair any damage caused to their genome.
A research team has made a novel finding that indicates that experimental antibody treatments for Alzheimer’s disease have an accidental adverse impact.
On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.
Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.
To design effective strategies that protect significant agricultural crops from climate change, it is important to understand how plants react to stressful environmental conditions.
Findings from a new study on Alzheimer's disease could eventually help clinicians identify people at the highest risk for developing the progressive brain disorder.
A City of Hope-led research team found that the same gene that increases the risk for Alzheimer's disease, ApoE4, can increase the susceptibility to and severity of COVID-19.
In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.
Scientists from The Mount Sinai Hospital and the National Center for Geriatrics and Gerontology based in Japan have recently discovered novel molecular mechanisms that drive late-onset Alzheimer’s disease (LOAD).
Scientists have devised a new method for isolating a kind of brain cell that is related to symptoms of Parkinson’s disease.
Alzheimer's disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole.
Transcription factor proteins can be described as the light switches of the human genome. These proteins bind to DNA and allow genes to turn “on” or “off.”
Scientists have created an animal model that simulates cerebellar neurodegeneration and motor dysfunction.
A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye.
According to a study, failures in a quality control system that defends protein-building fidelity in cells can result in motor neuron degeneration.
TK Adenosine triphosphate, or ATP, is the cellular energy currency that is as valuable to the human body as the dollar is to the US economy. Too high or too low levels of ATP in some cell types have been linked to a variety of diseases.
Researchers had identified an actin cytoskeketal nucleator, called Arp2/3 complex, more than 20 years ago.
Osaka, Japan - Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS).
Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies.
Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.