Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.
Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.
The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.
When a condition is connected to a genetic mutation, it is generally negative news.
Scientists at Rejuveron Vascular Therapeutics AG, a company specializing in the development of therapies to tackle neurodegeneration, are using INTEGRA’s VIAFLO 384 handheld electronic pipette to accelerate their research.
As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins.
Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.
Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.
Scripps Research scientists have discovered evidence that a chemical present in rosemary might be a two-pronged weapon against SARS-CoV-2.
Scientists discovered hundreds of proteins that are constantly transferred throughout the healthy brain in small membrane-enclosed sacs.
A thread-like highway, called microtubule tracks, allows motor proteins to transport cargo inside neurons.
A group of researchers recently unearthed vital information on how gene expression is orchestrated.
Proteins are the building blocks of all living things and numerous studies are carried out to determine how these proteins are made and their function.
Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.
Dementia is a condition that involves severe loss of cognitive function.
Findings published this week reveal new insights into the role of fat cells in cognitive decline and neurodegeneration, according to a study that involves the oxidant amplification loop led by Marshall University scientists.
Scientists from DZNE revealed that certain viral diseases can contribute to neurodegeneration.
Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain. The findings pave the way for treatments to combat a health problem that affects more than 40% of American adults.
Researchers from Northwestern Medicine distinguished different variants of the gene GRIK2 that induces nonsyndromic neurodevelopmental disorder (NDD).
Increasing evidence points to the fact that gut microbiota performs a vital role in regulating the advancement of neurodegenerative diseases like Alzheimer’s.
Research offers a new genetic tool to pinpoint C9orf72 repeat expansion-carrying frontotemporal lobar degeneration from huge population-based cohorts.