Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

UC San Diego Alpha Clinic awarded $8 million to bring new stem cell-based therapies to patients

Stem cells show particular promise in treating diseases for which few other effective treatments exist.

25 Nov 2022

Revitalized immune cells improve waste removal from the brain

Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.

11 Nov 2022

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

From The Max Planck Institute 20 Sep 2022

Researchers face challenges with stem cell lines that carry major DNA damage

Stem cells are a type of cell that can be configured to transform into almost any sort of cell in the body. They are presently used in research on organ development as well as in the initial phases of embryo development.

15 Aug 2022

Scientists demonstrate a new function of an enzyme that connects to age-related diseases

Aging and age-related diseases present a complex challenge to biomedical researchers.

20 Jul 2022

Researchers get a complete atlas of zebrafish genetic data for biomedical research

According to the latest research, medical and life science scientists will benefit from the most detailed atlas of zebrafish genetic data available.

5 Jul 2022

Research identifies the main gene that causes developmental disability syndrome

A single gene that was previously discovered to be the main factor in a rare disease associated with epilepsy, autism, and developmental delay has been named as a key player in the development of healthy neurons.

1 Jul 2022

New biomedical research tool may help advance molecular diagnostics and drug discovery

A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery.

30 Jun 2022

Researchers determine intracellular antibodies to cure diseases

Mermaid Bio GmbH of Munich, Germany, and WEHI of Melbourne, Australia, recently announced cooperation to identify and develop a unique class of therapeutic candidates that modify misbehaving proteins inside cells that can cause a variety of diseases.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 1 Jun 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Research associates autophagy and age-related nervous system degradation

The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.

20 Apr 2022

Noncoding DNA mutations prevent the brain from amyotrophic lateral sclerosis

When a condition is connected to a genetic mutation, it is generally negative news.

4 Apr 2022

INTEGRA’s VIAFLO 384 proves indispensable in neurodegeneration research

Scientists at Rejuveron Vascular Therapeutics AG, a company specializing in the development of therapies to tackle neurodegeneration, are using INTEGRA’s VIAFLO 384 handheld electronic pipette to accelerate their research.

From INTEGRA Biosciences 16 Mar 2022

Cryo-EM reveals how a bacterial protein senses and rescues stalled ribosomes

As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins.

11 Mar 2022

Novel molecular pathway shared by ALS and frontotemporal dementia identified

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

1 Mar 2022

New study uncovers potential driver of Parkinson’s disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.

24 Feb 2022