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Scientists Gain Insights into Biophysical Properties of Neurons with New Workflow

Biophysically detailed neuronal models provide a unique window into the workings of individual neurons.

5 Oct 2023

Brain's Choreography of Movement Unveiled in Zebrafish Study

The zebrafish brain, though simpler than its human counterpart, is a complex network of neurons that engage in a ceaseless dance of electrical activity.

11 Sep 2023

Bats' Navigation Brain Cells Also Encode Social Information

The same neurons that help bats navigate through space may also help them navigate collective social environments, finds a new study published today in the journal Nature.

31 Aug 2023

The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated Neurons

Studying the complex interactions between synaptic nerve endings as well as their development has now become much easier.

30 Aug 2023

Global Map of How the Animal’s Nervous System is Organized to Control Behavior

To understand the full relationship between brain activity and behavior, scientists have needed a way to map this relationship for all of the neurons across a whole brain-;a so far insurmountable challenge.

22 Aug 2023

Noelin1-3 Proteins Have Major Influence on Learning and Memory Formation in the Mammalian Brain

A German-American research team headed by Prof. Dr. Bernd Fakler from the Faculty of Medicine at the University of Freiburg demonstrated the major influence of Noelin1-3 proteins on learning and memory formation in the mammalian brain.

21 Aug 2023

Aging Disrupts Gene Expression in Specific Regions of the Brain

Most of us who've reached middle age have noticed a slowing in memory and cognition, but scientists don't have a clear picture of the molecular changes that take place in the brain to cause it.

18 Aug 2023

Noelin Proteins’ Key Role in Strengthening Neuronal Signals

As per a research study in mice from the National Eye Institute (NEI) and the University of Freiberg, Germany, the Noelin family belonging to secreted proteins bind to the exterior part of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane.

17 Aug 2023

Reprogramming Human Cells to Mimic Embryonic Stem Cells

Australian scientists have overcome a long-standing challenge in regenerative medicine in a remarkable discovery published in Nature.

17 Aug 2023

The Role of the Golgi Apparatus in the Development of Postnatal Neurons

Neurons are the cells that constitute brain circuits and employ chemicals and electricity to receive and transmit information that allows the body to perform anything from thinking to sensing to movement.

31 Jul 2023

Lactate Signaling Found to Be Critical for Neuronal Differentiation

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

25 Jul 2023

Developing a Fluorescent Sensor to Visualize Neuronal Self-Connectivity

How do brain cells, or neurons, distinguish their own processes and those of other neurons when they send out processes to connect with other neurons? A molecule known as clustered protocadherin (Pcdh) plays an important role in this puzzle.

19 Jul 2023

Novel Drug Compound Reduces Sensory Hypersensitivity in Fragile X Mice

Boosting the activity of inhibitory interneurons in Fragile X mice reduced their hypersensitivity to sensory stimuli, according to a new Neuron study led by UCLA Health researchers.

14 Jul 2023

Glucose-Sensing Neurons May Play a Role in Regulating Blood Sugar

The body's blood glucose level needs to be maintained in a relatively narrow range. It cannot be too high, as it can lead to diabetes, and it cannot be too low because it can cause fainting or even death.

12 Jul 2023

Analyzing Glioma Progression and Implicating CPNs’ Long-Range Projections

Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor. Despite treatment, GBM recurrence is inevitable and tends to occur outside surgical margins or in locations remote to the primary tumor, highlighting the central role played by tumor infiltration in this malicious disease.

29 Jun 2023

Review: Role of Alternative Splicing Defects in Major Neurodegenerative Diseases

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs -; single-stranded RNAs involved in protein synthesis -; and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

New Mechanism to Maintain Astrocyte-Neuron Communication

Neurons and astrocytes are the two types of cells required by the brain to enjoy the scent of morning coffee and freshly baked cookies or to discern the warning smell of something burning.

16 Jun 2023

Novel Technique Overcomes Challenges of Bioprinting

Printing living cells into functional tissues is a highly complex process, and with each technological advancement, new challenges emerge. The Levato lab at UMC Utrecht has successfully combined two promising printing processes to boost cell density, cell survival, and specialization in bioprints. The solution: granular biogels or resins.

8 Jun 2023

Scientists Discover the Mechanisms of Synaptic Pruning in Brain Development

Researchers at Kyushu University have uncovered the mechanisms of a fundamental yet critically under-looked phase in brain development: synaptic pruning.

8 Jun 2023

High-Resolution, Stable Brain Stimulation by Ultraflexible Nanoelectrodes

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

31 May 2023