Neurons News and Research

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Gene governing cell division could shield against Alzheimer’s

According to a recent study by researchers at the University of Colorado Anschutz Medical Campus, the overexpression of a gene linked to cell division and the structure and function of neurons could prevent and protect against cognitive deterioration in both mice and people with Alzheimer’s disease (AD).

28 Oct 2022

Key to developing more effective obesity treatments

The amygdala, a part of the brain, is in charge of strong emotions such as fear. Scientists have shown that the amygdala may be at fault for overeating.

25 Oct 2022

Nonconducting W434F mutant varies in structure and conformation

Potassium (K+) channels are tiny, highly specialized conduits found in every live cell that transfer K+ ions in an exceedingly selective and quick manner across cell membranes.

13 Oct 2022

Spores integrate environmental signals over time

When exposed to starvation and stress, certain bacteria enter a dormant state in which life functions cease. These cells, known as spores, can resist punishing extremes of heat, pressure, and even the extreme conditions of outer space by entering a profound hibernation.

7 Oct 2022

Cell illumination and targeted cell editing using RNA-based editing technology

An RNA-based editing tool has been developed by Duke University researchers, which targets specific cells rather than genes. Any cell type can be precisely targeted, and any protein of interest can be added only to that cell type.

6 Oct 2022

New guidelines to generate high-quality, well-structured organoids

Researchers have opened a new avenue for investigations of neurological development, disease, and therapies that cannot be undertaken in living people by employing stem cells to grow small brain-like structures in the lab.

30 Sep 2022

Researchers use zebrafish larvae to study how the brain reacts to warmer temperatures

Which organisms survive and which succumb when the climate changes? A small larval fish is providing surprising insight into how the brain reacts when the temperature rises.

30 Sep 2022

New role for huntingtin protein—neuronal regeneration

A recent study led by the University at Buffalo proposes a novel role for the huntingtin protein (HTT), which leads to Huntington’s disease when mutated.

28 Sep 2022

An analysis of old genes’ influence on sea anemones

For the neuronal cell types’ categorization as more complicated creatures, the genetic fingerprint of Nematostella vectensis—the sea anemone—reveals that the members of this evolutionarily very ancient animal phylum employ identical gene cascades.

22 Sep 2022

Researchers reveal key developmental difference between the brains of modern humans and Neanderthals

AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neanderthals, due to the change of a single amino acid in the protein TKTL1.

From The Max Planck Institute 20 Sep 2022

Human-specific gene involves in neocortical expansion during evolution

Great ape animal experiments have long been prohibited in Europe due to ethical concerns. An alternative to using animals in investigations is the use of organoids, which are three-dimensional cell structures that can be generated in the lab and are only a few millimeters in size.

From The Max Planck Institute 14 Sep 2022

Characterizing the transcription profile of microglia in a mouse model

Researchers from Tohoku University have now shown that the consolidation and extinction of contextual fear conditioning alter the microglial genes connected to the synapse—structures that permit neurons to communicate with one another.

13 Sep 2022

The deep relationship between Tob gene and common mental health conditions

The Tob gene is well known for its connection to cancer. Scientists have discovered that this gene also has a significant role in lowering depression, fear, and anxiety in a multidisciplinary study that blends molecular biology with neuroscience.

12 Sep 2022

Spatial transcriptomic data highlights the features of the axolotl brain

The first spatiotemporal cellular atlas of axolotl (Ambystoma mexicanum) brain growth and regeneration, created by a multi-institute research team under the direction of BGI-Research, reveals how brain damage may recover itself.

8 Sep 2022

Generalizable strategy to program gene stability of microbial communities

Biomedical engineers at Duke University have revealed a microbial community phenomenon that is analogous to teaching neighbors how to perform critical jobs by ripping out and sharing parts of the brain.

8 Sep 2022

Simple blood test helps identify patients developing neurotoxic side effects

The treatment of various tumors has been transformed by cell-based immunotherapy, often known as CAR-T cell therapy. To target and combat specific forms of leukemia and lymphoma, the treatment employs genetically engineered T cells.

8 Sep 2022

Brain cells with the same birthdate display distinct connectivity

According to a recent study, brain cells with the same “birthdate” are more likely to connect into cooperative signaling circuits that perform a variety of tasks, including memory storage.

From New York University (NYU) 25 Aug 2022

Scientists discover latent stem cells that respond to injury in the central nervous system of mice

Scientists at the Francis Crick Institute have identified a group of latent stem cells that respond to injury in the central nervous system of mice. If a similar type of cell exists in humans, they could offer a new therapeutic approach to treat brain and spinal cord injuries.

23 Aug 2022

Engineers develop the world's smallest EEG caps for mini brains

It could be the world's tiniest EEG electrode cap, created to measure activity in a brain model the size of a pen dot. Its designers expect the device to lead to better understanding of neural disorders and how potentially dangerous chemicals affect the brain.

18 Aug 2022

Researchers face challenges with stem cell lines that carry major DNA damage

Stem cells are a type of cell that can be configured to transform into almost any sort of cell in the body. They are presently used in research on organ development as well as in the initial phases of embryo development.

15 Aug 2022