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Method can help detect specific glial cells integral to synapses

The brain contains two types of cells. Glial cells receive less attention for their significance in the function and disease of the brain than other neurons.

From Brown University 26 Jun 2020

Researchers discover new druggable pathway linked with tuberous sclerosis

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

25 Jun 2020

Genetic dysfunction of brain astrocytes promotes head pain in familial migraine

Neuroscientists of the University of Zurich shed a new light on the mechanisms responsible for familial migraine: They show that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence.

25 Jun 2020

Astrocytes may play a key role in neurodegenerative disorders

According to a new research performed in rodents, cells that usually nurture nerves may actually destroy them following a brain injury.

From New York University (NYU) 24 Jun 2020

Alzheimer's: New Gene May Drive Earliest Brain Changes

A newly discovered Alzheimer's gene may drive the first appearance of amyloid plaques in the brain, according to a study led by researchers.

23 Jun 2020

Scientists substantiate the existence of concept cells in the brain

For the first time, a team of researchers from Lobachevsky University has theoretically validated the existence of concept cells.

19 Jun 2020

Novel silicon-based antioxidant agent may prevent kidney failure and Parkinson's disease

Oxidative stress is the result of reactive oxygen species (ROS) generation, and can be damaging to cells and tissues.

From Osaka University 19 Jun 2020

Study reveals mechanism by which propionic acid induces brain disorders

Korea Brain Research Institute (KBRI, headed by Suh Pann-ghill) announced on the 11th that the research team led by Dr. Mun Ji-young revealed the mechanism of autism induced by an imbalance of human gut microorganisms.

19 Jun 2020

cryo-EM images reveal proteins involved in brain activity

When the body continues to perform its daily biological processes neurotransmitters, regulate the level of electrical activity inside the brain.

18 Jun 2020

Gut bacteria may modify host animal's behavior, influence food choices

Gut bacteria are tiny but may play an outsized role not only in the host animal's digestive health, but in their overall well-being.

18 Jun 2020

Solving A Parkinson's Disease Puzzle Through Protein Design

Dopamine is a neurotransmitter involved in everything and the receptors have been a longstanding target for treating disorders like Parkinson's disease.

17 Jun 2020

Fish Oil May Help With Depression

A study shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.

17 Jun 2020

Activating specific neurons can trigger hibernation-like state in mice

In Sci-Fi movies, astronauts often enter an inactive state in "hibernation chambers" to cross the vastness of space.

15 Jun 2020

Inhibitory interneurons excite the developing brain, study finds

Brain function depends on inhibitory cells that balance or 'brake' excitation. These neurons allow the brain to process information and also prevent runaway seizures.

15 Jun 2020

New protein design could help in drug discovery for Parkinson’s disease

The neurotransmitter dopamine plays a vital role in everything, starting from motor control to higher cognitive functions, arousal, motivation, sexual gratification, and reinforcement.

12 Jun 2020

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.

11 Jun 2020

Interaction between neurons and glial cells boosts appetite

Tanycytes are essentially glial cells, which interact with neurons in the brain to inform this organ about the type of food consumed by individuals.

From The University of Warwick 9 Jun 2020

Automated 3D brain imaging data analysis helps unravel complex neural circuits

Automated 3-D brain imaging data analysis technology offers more reliable and standardized analysis of the spatial organization of complex neural circuits.

9 Jun 2020

Single-cell-resolution technologies help map brain regions in humans and primates

Using the single-cell-resolution transcriptomics technologies, researchers have performed a large-scale analysis of gene expression in 33 different brain regions of chimpanzees, bonobos, macaques, and humans, and successfully generated a map of the various brain regions with their particular cell structures.

5 Jun 2020

Study uncovers why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

4 Jun 2020