Neurosurgery News and Research

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Inhibiting astrocyte hyperactivity can reverse cognitive deficits associated with social deprivation

Here is an important reason to stay in touch with friends and family: social isolation causes memory and learning deficits and other behavioral changes.

15 Feb 2023

Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Notalgia paresthetica-;a nerve disorder characterized by a persistent itch in the upper back-;is a common and underdiagnosed condition worldwide.

9 Feb 2023

Innovative approach to mRNA delivery

A group of scientists spearheaded by The University of Texas MD Anderson Cancer Center has created a unique messenger RNA (mRNA) delivery system utilizing extracellular vesicles (EVs).

16 Jan 2023

A more efficient way to deliver gene therapies to the CNS

For gene therapy, the blood-brain barrier (BBB) poses a formidable obstacle. The BBB, which is made up of cells that are closely packed together, prevents poisons and pathogens from accessing brain tissue while also blocking potential treatments for diseases that impact the CNS.

12 Oct 2022

Cell illumination and targeted cell editing using RNA-based editing technology

An RNA-based editing tool has been developed by Duke University researchers, which targets specific cells rather than genes. Any cell type can be precisely targeted, and any protein of interest can be added only to that cell type.

6 Oct 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Cedars-Sinai builds bio-realistic and intricate computer models of brain cells

Researchers at Cedars-Sinai have produced an unprecedented number of bio-realistic and intricate computer models of individual brain cells.

11 Aug 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Elective course in biodesign enables students to expand their abilities as medical device innovators

Educators at the Renaissance School of Medicine (RSOM) at Stony Brook University highlighted the success of their three-year, elective course in biodesign that has enabled students to expand their abilities as innovators to creating potential medical devices for the future.

11 May 2022

Researchers discover how new techniques may alter the synaptic connection of neurons

The brain has the potential to change the way neurons communicate with one another. That is how it prevents out-of-control brain activity. Scientists have discovered a mechanism that plays a key role in this.

21 Apr 2022

Genomics provides a deeper understanding of the cause of hydrocephalus

The cerebral ventricles—four linked cavities of the brain that are packed with cerebrospinal fluid—become enlarged in hydrocephalus, or “water on the brain;” however, the cause is unknown in many instances.

20 Apr 2022

Bioprinting bone along with two growth factor encoding genes improves bone repair

Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing.

From Penn State University 13 Apr 2022

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

High-resolution 3D map reveals cellular structure of the human metathalamus

A new, high-resolution 3D map of a previously unmapped area of the brain has been reconstructed by a team of researchers as part of the Human Brain Project (HBP). The German-based group developed a cytoarchitectonic map (a map of the cellular structure of the brain, down to the individual neurons) of the metathalamus, an area involved in processing audiovisual information.

4 Apr 2022

Study identifies two types of brain cells that play a key role in creating memories

In a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human experience into distinct segments that can be recalled later.

8 Mar 2022

New method helps distinguish bacterial DNA from human and other non-bacterial cells

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

4 Feb 2022

Neurosurgery News and Research

Inhibiting astrocyte hyperactivity can reverse cognitive deficits associated with social deprivation

Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Innovative approach to mRNA delivery

A more efficient way to deliver gene therapies to the CNS

Cell illumination and targeted cell editing using RNA-based editing technology

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Cedars-Sinai builds bio-realistic and intricate computer models of brain cells

Researchers devise a new treatment approach to cure aggressive brain tumors

Elective course in biodesign enables students to expand their abilities as medical device innovators

Researchers discover how new techniques may alter the synaptic connection of neurons

Genomics provides a deeper understanding of the cause of hydrocephalus

Bioprinting bone along with two growth factor encoding genes improves bone repair

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

High-resolution 3D map reveals cellular structure of the human metathalamus

Study identifies two types of brain cells that play a key role in creating memories

New method helps distinguish bacterial DNA from human and other non-bacterial cells

Researchers catalog the complete cells that form the blood vessels of the human brain

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Changes in the activity of gene networks may explain arteriosclerosis risk

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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