Neutrophils News and Research

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Study sheds light on blood and immune systems development in prenatal bone marrow

Researchers carried out the first extensive investigation of the formation of the blood and immune systems in the prenatal bone marrow.

4 Oct 2021

Newly identified antibacterial mechanism could inspire novel strategies to combat bacterial pathogens

Similar to how a spider traps its prey, the cells of the human immune system cooperate to trap and “eat” bacteria.

14 Sep 2021

Scientists are paving the way for cancer treatments with fewer side effects

In recent years, immunotherapy has revolutionized the field of cancer treatment. However, inflammatory reactions in healthy tissues frequently trigger side effects that can be serious and lead to the permanent discontinuation of treatment.

5 Jul 2021

Researchers analyze and describe immune cells in the human bile duct

The immune cells that reside in the human bile duct have been studied and described in depth by researchers at Karolinska Institutet.

25 Jun 2021

Prevalent protein in the blood plays a vital role in human fertilization, infection resistance

Albumin activates a proton channel which allows sperm to penetrate and fertilize an egg and white blood cells to secrete large amounts of inflammatory mediators.

23 Jun 2021

New fluorescent probe that can discriminate B lymphocytes over T lymphocytes

Human blood contains several different components, including plasma, red blood cells (RBCs), white blood cells (WBCs), and platelets.

15 Apr 2021

Key molecule determines the pathogenesis of lupus

A new research work, published in JCI, has discovered that the endoplasmic reticulum of a neutrophil becomes stressed in the autoimmune disorder lupus.

29 Mar 2021

Immune receptor proteins can help treat autoimmune diseases

TARM1 is a receptor protein, whose function in the working of the immune system is not known yet. Now, in a new research work, Japanese researchers have analyzed mouse models to investigate the promising role of TARM1 protein in the pathogenesis of rheumatoid arthritis.

From Tokyo University of Science 18 Mar 2021

Mast Cells: High-speed messengers of the immune defense

In order to fight pathogens, mast cells regulate inflammatory reactions of the immune system.

10 Feb 2021

Main bioactive compound of ginger root counteracts autoimmune diseases in mice

Naturopathic medicine, or herbal medicine, is all the rage, especially among young people. But how much of this is supported by science?

7 Jan 2021

White blood cells can be trained to attack tumor cells

Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.

9 Nov 2020

Scientists identify a genetic basis for ANCA-associated vasculitis

Autoimmune disease is fundamentally a mystery: whyever should an organism systematically set out to harm itself? Now, researchers at the University of Tsukuba have identified a genetic basis for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, an autoimmune systemic disease that damages organs by targeting small blood vessels in a genetic association study.

5 Nov 2020

'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Anti-inflammatory mediator could play key role in wound healing

"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.

27 Oct 2020

Study pinpoints specific protein involved in the mass production of antibodies

A team of researchers has discovered how a specific protein called JAGN1 plays a crucial role in the production of antibodies.

17 Sep 2020

Study shows immune cells contribute to brain infection

A new study shows how the immune system has a damaging effect on a severe brain condition, which is most commonly caused by the cold sore virus.

17 Sep 2020

Sticky DNA webs may cause tissue damage linked to severe COVID-19

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published on September 14 in the Journal of Experimental Medicine (JEM).

15 Sep 2020

LJI scientists tracked down rare stem cells that generate neutrophils in humans

Neutrophils are the warriors of the immune system. They are always ready to spring to action to help heal injuries or fight off disease. Unless, that is, something goes wrong in their developmental process.

19 Aug 2020

Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Researchers from the Albert Einstein College of Medicine have demonstrated that chronic psychological stress can result in painful vessel-clogging episodes—a frequent cause of hospitalizations and the most typical complication of sickle-cell disease or SCD.

31 Jul 2020