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The Role of CRISPR-Cas9 in Treating Primary Immunodeficiency Disorders

Severe Combined Immunodeficiencies (SCIDs) encompass a collection of serious primary immunodeficiency disorders primarily instigated by genetic mutations that disrupt the development of T-cells.

30 Oct 2023

Novel Replacement Strategy Opens the Door to Therapeutic Interventions for Genomic Diseases

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development.

27 Oct 2023

Broken String Biosciences Strengthens Senior Leadership Team to Accelerate Product Development and Commercialization

Broken String Biosciences today announced the expansion of its senior leadership team with the appointments of Vincent Smith, PhD, as Chief Technology Officer and Jessica Rich as VP Business Development.

3 Oct 2023

NC State Researchers Develop New Method to Produce Seedless Plants

North Carolina State University researchers have successfully transferred an important gene from one compartment of a plant cell to another to produce tobacco plants that lack pollen and viable seeds, while otherwise growing normally.

19 Sep 2023

Researchers Develop New Way to Genetically Suppress Malaria-Carrying Mosquitoes

Malaria remains one of the world's deadliest diseases. Each year malaria infections result in hundreds of thousands of deaths, with the majority of fatalities occurring in children under five.

6 Jul 2023

Assembled DNA Nanostructures Without the Use of Magnesium Yield Greater Stability

Researchers at the University at Albany’s RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium.

7 Jun 2023

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Researchers have developed a chicken egg that may be safe for people with egg white allergies. Chicken egg allergies are one of the most common allergies in children.

18 May 2023

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 is frequently used to alter the genome by researching and editing disease-related genes. However, this approach is coupled with undesirable side effects including mutations and toxicity.

11 Apr 2023

Researchers expand the known defensive abilities of CRISPR–Cas systems

Viruses can infect bacteria and archaea, just as they can humans. These microbes have evolved their own immune defense mechanisms to combat their pathogens. Bacterial defenses, like CRISPR-Cas systems, contain a variety of proteins and functions that aid bacteria in protecting themselves from foreign intruders.

5 Jan 2023

New CRISPR RNA-guided Caspases could lead to promising antiviral and tissue engineering tools

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

26 Aug 2022

New technology can help detect the activity of CRISPR gene editing tools

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy's Oak Ridge National Laboratory.

13 Dec 2021

Study unravels the DNA repair mechanism by enzymes

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Nuclease News and Research

The Role of CRISPR-Cas9 in Treating Primary Immunodeficiency Disorders

Novel Replacement Strategy Opens the Door to Therapeutic Interventions for Genomic Diseases

Broken String Biosciences Strengthens Senior Leadership Team to Accelerate Product Development and Commercialization

NC State Researchers Develop New Method to Produce Seedless Plants

Researchers Develop New Way to Genetically Suppress Malaria-Carrying Mosquitoes

Assembled DNA Nanostructures Without the Use of Magnesium Yield Greater Stability

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Optimized Genome-Editing Method Vastly Reduces Mutations

Researchers expand the known defensive abilities of CRISPR–Cas systems

New CRISPR RNA-guided Caspases could lead to promising antiviral and tissue engineering tools

New technology can help detect the activity of CRISPR gene editing tools

Study unravels the DNA repair mechanism by enzymes

Newly identified antibacterial mechanism could inspire novel strategies to combat bacterial pathogens

Study shows that autophagy plays a key role in messenger RNA degradation

Study highlights the importance of autophagy in gene regulation

Study reveals mechanisms behind the activation of MRN complex

New study facilitates the use of gene editing technique on plants

Newly identified Cas9 nucleases can improve genome editing

Researchers determine 3D structures of RNA hybridization with artificial nucleic acids

Exploiting CRISPR systems for the fast detection of SARS-CoV-2

The Exclusome, A New Mammalian "Containter"

Breaking Down the Onso System: PacBio's Genomic Advancement

The Last Piece of Our Genome: Sequencing the Y Chromosome

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