Nucleotide News and Research

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The Genetic Secret Behind Human Skull Morphology

Researchers at the Universities of Helsinki, Barcelona, and Tokyo Medical and Dental University (TMDU) have discovered a single nucleotide alteration that is crucial to the evolution of human skull morphology and influences the expression of the TBX1 gene and the formation of the skull base.

18 Apr 2024

Deciphering the Significance of m6A RNA Modification in HIV-1 Genome

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells, a new study has found.

13 Apr 2024

Study Reveals Structure of Two Nucleic Acid-Degrading Enzymes

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

3 Apr 2024

Microsatellites' Stability Through Deep Time: Insights from Adélie Penguin Genomes

Microsatellites are valuable tools for studying inheritance, genetic diversity, and population dynamics across a wide range of organisms including bacteria, plants, animals, and fungi. These

2 Apr 2024

Development of a Rapid miRNA Detection Method Based on Rolling Circle Amplification

This study is led by Professor Jue Ruan (Chinese Academy of Agricultural Sciences, Shenzhen, China). The authors developed a one-pot isothermal detection method based on rolling circle amplification (RCA) for rapid and specific detection of miRNAs and short RNA fragments.

30 Mar 2024

Key Insights into LAR-RPTP's Synaptic Regulation via Microexon Molecular Codes

The Synapse Diversity and Specificity Regulation Research Team (Director: Jaewon Ko) at DGIST (President Kunwoo Lee) reported on Tuesday the 27th that they have profiled the molecular code that constitutes brain neural circuits and discovered that it regulates specific excitatory synapse characteristics that contribute to memory of new object locations.

30 Mar 2024

AI Tool Discovers Hidden Diversity in Major Crops

Researchers have created a new computational tool that quickly and effectively exposes genetic variety inside DNA databases of different plant species, which is a significant advancement for agricultural science.

21 Mar 2024

DNA Origami Revolutionizes Cancer Immunotherapy: The DoriVac Breakthrough

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024

Quantifying Strain Variability in Natural Bacterial Populations

Researchers led by Kostas Konstantinidis from the Georgia Institute of Technology developed a novel approach to categorize bacteria into distinct species and strains, addressing a long-standing challenge in microbiology.

5 Mar 2024

New Research Supports Concept of "RNA World"

The Salk Institute’s most recent research offers new perspectives on the beginnings of life and strong evidence in favor of the RNA World theory.

5 Mar 2024

Retrotransposon-Based PRINT Technique Holds Potential for Precise Gene Insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

22 Feb 2024

CAR Peptide Accelerates Tissue Repair and Minimizes Scarring

Accelerating tissue injury repair while preventing the formation of less functioning scar tissue in the injured areas is one of the main objectives of medical science.

15 Feb 2024

Researchers Reveal Evolutionary Origin of Mysterious Immune System Molecule in Humans

Biological systems can behave as siblings in several ways, including by borrowing something and never giving it back.

31 Jan 2024

Study Sheds Light on a Decades-Long Mystery About How Retinal Photoreceptors Work

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical "vision" signals to the brain.

27 Jan 2024

Implications of the KMAP Ocean Gene Catalog 1.0

The greatest investigation of ocean DNA reveals the diverse world of ocean bacteria. The KMAP Global Ocean Gene Catalog 1.0, an open-source database containing over 317 million gene groups, has the potential to stimulate biotechnology innovation and reveal the function of marine microbes in reducing global warming and preserving human and environmental health.

17 Jan 2024

Investigating the Functional Mechanisms of RNA Replicase

It has long been a mystery how the complex molecular machinery of life sprang from modest beginnings.

17 Jan 2024

Uncovering How Tomatoes Fight Off Notorious Blight

Recently, The Plant Journal’s cover highlighted an innovative study that has garnered attention in the interesting field of plant biology.

10 Jan 2024

Genetic Twist in Tiny Protein Protects Against Parkinson's

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

3 Jan 2024

Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023