Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.
A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.
Researchers at the University of Illinois Chicago have designed a high-quality assay that can be used in at-home tests for rapid COVID-19 screening.
Immunotherapies called chimeric antigen receptor (CAR) T cells use genetically engineered versions of a patient's own immune cells to fight cancer. These treatments have energized cancer care, especially for people with certain types of blood cancers.
Receptors are docking stations found on the surface of cells. Compounds such as caffeinE, dopamine, THC, and LSD, all bind to these receptors.
Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.
Without doubt, the future of life sciences is sure to have technology that can measure biological parameters real-time in living organisms.
Scientists for the first time developed a nano computing agent that regulates the function of a specific protein involved in cell movement and cancer metastasis.
University of Calgary researchers probing the gut -; "the inner tube of life" -; have for the first time discovered specific factors in its workings that in the future may help improve treatment for patients facing gut damage or gastrointestinal disease.
Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.
Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night.
Comprehending how proteins twist, bend, and shape-shift, as they work in cells, is vital to gain insights into diseases and normal biology.
A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.
Scientists from the Karolinska Institutet pinpointed a protein that enhances motor coordination, muscular metabolism, and exercise performance in mice.
Researchers elucidate why certain drugs, in clinical trials, for treating a kind of acute myeloid leukemia often fail and revealed a means to restore their efficacy.
When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.
Researchers from Northwestern Medicine distinguished different variants of the gene GRIK2 that induces nonsyndromic neurodevelopmental disorder (NDD).
Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.
A new study reports that circulating tumor cells that exhibit the features of stem cells employ ICAM1 to enable the formation of CTC clusters.
Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs.
Studying the role genes play on basic biology and disease is now easier, faster and more efficient, say researchers at Baylor College of Medicine.