Pharmacology News and Research

RSS

Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.

Research may lead to new therapies for metabolic disorders and other diseases

Researchers at UT Southwestern have uncovered a molecular path that allows cells to detect when their lipid supplies are running low, triggering a flurry of activity that avoids starvation.

23 May 2022

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Prostate cancer that has spread to other regions of the body is commonly treated with hormone treatment, but many individuals develop resistance to it, making their disease more aggressive and potentially fatal.

12 May 2022

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Spatial maps offer insights into the battle between melanoma cells and immune cells

Melanoma is a somewhat unusual cancer-;one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs.

From Harvard Medical School 15 Apr 2022

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

In new research, UT Southwestern scientists report that imaging a key immunity protein known as STING at near-atomic resolution reveals a previously undiscovered binding location that appears to be crucial for launching immunological attacks.

11 Apr 2022

Gut microbiota may play a role in resistance to blood pressure medicines

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

6 Apr 2022

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Researchers have identified a family of proteins that is significantly elevated in the saliva of patients hospitalized with COVID-19.

5 Apr 2022

Researchers identify new set of protein biomarkers for cancer using breast milk

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

5 Apr 2022

Older rats more vulnerable to caffeine-induced ventricular tachyarrhythmia than younger ones

The Food and Drug Administration recommends healthy adults not exceed 400 milligrams (mg) of caffeine-; approximately four cups of brewed coffee-; a day.

4 Apr 2022

Plant compound may be a good therapeutic candidate for treating food allergies

Researchers combined advanced computational methods with experimental studies to gain new insight, at the cell level, into how the plant compound formononetin might be used to treat food allergies.

4 Apr 2022

Researchers discover a unique technique to fight hospital-borne disease

A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.

From New York University (NYU) 4 Apr 2022

Researchers show how proteins form DNA-repair mechanism in living bacteria

Two recent research have shown a completely new perspective of how bacterial cells repair broken parts of their DNA (lesions).

From New York University (NYU) 1 Apr 2022

ATM kinase inhibitor combines with target therapies to wipe out cancer cells

While cancer therapies that target specific genes or disease pathways might prolong life span, they can also result in highly resistant tumors when tiny reservoirs of cancer cells survive therapy, develop, and spread.

1 Apr 2022

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice.

31 Mar 2022

Researchers analyze a powerful tool to enhance drug discovery

Hormones or chemical messengers link to cell membrane receptors to tweak how the cell responds, creating a metaphorical interaction and traffic network on the surface of cell membranes inside human body.

23 Mar 2022

Novel mechanistic insight into how gut bacteria work to tame intestinal inflammation

Bile acids made by the liver have long been known for their critical role in helping to absorb the food we ingest.

From Harvard Medical School 17 Mar 2022

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.

14 Mar 2022

Pharmacology News and Research

Research may lead to new therapies for metabolic disorders and other diseases

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Spatial maps offer insights into the battle between melanoma cells and immune cells

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

Gut microbiota may play a role in resistance to blood pressure medicines

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Researchers identify new set of protein biomarkers for cancer using breast milk

Older rats more vulnerable to caffeine-induced ventricular tachyarrhythmia than younger ones

Plant compound may be a good therapeutic candidate for treating food allergies

Researchers discover a unique technique to fight hospital-borne disease

Researchers show how proteins form DNA-repair mechanism in living bacteria

ATM kinase inhibitor combines with target therapies to wipe out cancer cells

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

Researchers analyze a powerful tool to enhance drug discovery

Novel mechanistic insight into how gut bacteria work to tame intestinal inflammation

Insight into oligodendrocyte cells could lead to new treatments for neurodegenerative diseases

Astrocyte networks are essential for spatial learning and memory formation, study shows

Researchers identify the underlying molecular mechanism for development of chronic pain

Central signaling pathway likely to help reduce the progression of autoimmune disorders

Drug Discovery eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics