Pharmacology News and Research

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Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.

New discovery offers insight into how cells maintain the integrity of DNA

Researchers from Case Western Reserve University have identified a new mechanism by which a protein known for repairing damaged DNA also protects the integrity of DNA by preserving its structural shape.

19 Jan 2022

Scientists examine key mechanisms underlying genomic imprinting

Hereditary diseases, along with cancers and cardiovascular diseases, may be linked to genomic imprinting.

13 Jan 2022

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

Researchers at the University of Illinois Chicago have designed a high-quality assay that can be used in at-home tests for rapid COVID-19 screening.

4 Jan 2022

Researchers develop new CAR T cells that act as a "micropharmacy"

Immunotherapies called chimeric antigen receptor (CAR) T cells use genetically engineered versions of a patient's own immune cells to fight cancer. These treatments have energized cancer care, especially for people with certain types of blood cancers.

3 Jan 2022

New computational method could help quickly screen billions of drug compounds

Receptors are docking stations found on the surface of cells. Compounds such as caffeinE, dopamine, THC, and LSD, all bind to these receptors.

17 Dec 2021

Driving up the immune response at tumor site may help boost immunotherapy

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

15 Dec 2021

Scientists develop advanced imaging technique to analyze oxygenation within bone tissue

Without doubt, the future of life sciences is sure to have technology that can measure biological parameters real-time in living organisms.

23 Nov 2021

Study results facilitate construction of complex nanoscale computing agents

Scientists for the first time developed a nano computing agent that regulates the function of a specific protein involved in cell movement and cancer metastasis.

From Penn State University 19 Nov 2021

Microbiome discovery may help improve treatment for patients facing gut damage

University of Calgary researchers probing the gut -; "the inner tube of life" -; have for the first time discovered specific factors in its workings that in the future may help improve treatment for patients facing gut damage or gastrointestinal disease.

15 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Mitochondria of diabetic patients can't keep track of time, study finds

Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night.

21 Oct 2021

Novel technique shows molecule conformations in live cells

Comprehending how proteins twist, bend, and shape-shift, as they work in cells, is vital to gain insights into diseases and normal biology.

21 Oct 2021

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

12 Oct 2021

Experts state muscle-secreted neurturin provides similar results as exercise

Scientists from the Karolinska Institutet pinpointed a protein that enhances motor coordination, muscular metabolism, and exercise performance in mice.

1 Oct 2021

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Researchers elucidate why certain drugs, in clinical trials, for treating a kind of acute myeloid leukemia often fail and revealed a means to restore their efficacy.

1 Oct 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, shows study

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021