Phosphatase News and Research

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Study Reveals Structure of Two Nucleic Acid-Degrading Enzymes

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

3 Apr 2024

Algal Blooms May Pose More Health Risks Than Previously Thought

Florida's 156-mile-long Indian River Lagoon (IRL) borders five different counties and has five inlets that connect the lagoon with the Atlantic Ocean.

16 Jan 2024

Salmonella Employs Unique Tactics to Escape Cellular Defense

Salmonella enterica, a disease-causing bacterium, employs a variety of strategies to evade the human body’s defense mechanisms, much like thieves.

29 May 2023

New gene helps drive the development of the common lung cancer type

At the NYU Langone Health’s Perlmutter Cancer Center, a team headed by scientists has determined a gene that forces the development of the second most common type of lung carcinoma.

From New York University (NYU) 11 Jan 2023

Discovering H2O2 sensing capacity in plants that control immunity

All aerobic organisms produce the molecule hydrogen peroxide (H2O2). When present in low concentrations, it acts as a crucial secondary signal to control a variety of biological processes, including but not limited to plant-microbe interactions, abiotic stress tolerance, pollen tube growth, root hair formation, leaf cell expansion, and Casparian strip formation.

20 Oct 2022

Delicate strategy employed by pathogens to suppress pyroptosis

Mycobacterium tuberculosis (Mtb), the bacteria that causes tuberculosis (TB), continues to be a major infectious threat to global public health.

18 Oct 2022

Lager beer consumption may increase men’s gut microbiome’s diversity

Like wine, beer can have health benefits when consumed in moderation. Non-alcoholic beers have become wildly popular recently, but are these drinks also healthful?

16 Jun 2022

Scientists develop DNA-based fluorescent nanoantenna to evaluate protein activity

Researchers at the Université de Montréal have developed a nanoantenna to track protein movements.

13 Jan 2022

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Acute myeloid leukemia (AML) is an aggressive cancer of white blood cells with few effective targeted therapies available to treat it.

12 Jan 2022

Regulating the activity of a protein enhances health span, says research

Scientists from KAIST put forth novel insights for enhancing the health span by controlling a protein’s activity.

25 Nov 2021

Targeting Shp2 as a cancer therapy may worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

10 Nov 2021

Researchers identify novel cytokinin signaling component

The classical historic plant hormones, cytokinins, regulate different aspects of plant growth and development. These include crucial agronomic traits like grain number in rice.

19 Oct 2021

Study unravels novel centromeric functional protein

Scientists have discovered a new centromeric functional protein and dubbed it Adaptor of polo1 (Apolo1). The findings of the study were reported in Cell Reports.

27 Jul 2021

Insights on double-strand break repair may provide better understanding of cancer development

The BRCA1 protein known widely for its role in hereditary breast cancer is also a vital part of the cellular system repairing double-stranded DNA breaks.

From Osaka University 16 Jul 2021

Researchers explore the regulatory role of protein in human health and disease

Researchers from the University of Virginia, Lehigh University and the Massachusetts Institute of Technology are pooling their respective labs' expertise to unlock the mysteries of a protein that plays a critical regulatory role in human health and disease.

5 Feb 2021

Protein phosphatase inhibition could contribute to the treatment of cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Study shows how DUSP8 protein regulates glucose tolerance, insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

24 Aug 2020

Study reveals key biochemical processes that advance understanding of colorectal cancer

A new insight into cell signals that control cancer growth and migration could help in the search for effective anti-cancer drugs. A McGill-led study reveals key biochemical processes that advance our understanding of colorectal cancer, the third most common cancer among Canadians.

13 Aug 2020

Oxytocin can help control and prevent osteoporosis

Oxytocin, produced by the hypothalamus and sometimes known as the "love hormone" for its involvement in pair bonding and orgasm, can be a strong ally in the control and prevention of osteoporosis, according to a study by scientists at São Paulo State University in Brazil.

11 Aug 2020