Polymerase News and Research

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Bispecific antibodies for SARS-CoV-2 variant neutralization

Bispecific antibodies targeting multiple SARS-CoV-2 sites offer enhanced neutralization against emerging variants, advancing COVID-19 treatment strategies.

14 Mar 2025

Cryo-EM Reveals 3D Structure of Nipah Virus RNA Polymerase

The replication of the Nipah virus's genetic material in infected cells has been demonstrated for the first time by researchers from the Max Planck Institute (MPI) for Multidisciplinary Sciences and the University Medical Center Göttingen (UMG). In humans, the virus can cause fatal encephalitis.

11 Mar 2025

Low-Cost, Flexible Protein Detection Platform for Global Health

Chemical and biomolecular engineers at Georgia Tech have created a plug-and-play platform for the detection of disease protein biomarkers that is straightforward, adaptable, and user-friendly, eliminating the need for expensive laboratory equipment.

10 Mar 2025

Understanding TEFM's Role in mtDNA Stability

Mitochondrial deoxyribonucleic acid (mtDNA) is vital for cellular energy production and the overall functionality of cells.

6 Mar 2025

New CRISPR Method Enhances Surveillance of Antibiotic Resistance in Wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals.

4 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

Fruit Fly Immune Responses May Help Predict Human Susceptibility to New Viruses

Study on Drosophilidae shows positive correlations in viral susceptibility, highlighting evolutionary trends that may predict novel virus threats to humans.

12 Feb 2025

New Microfluidic Device can Detect SARS-Cov-2 with Revolutionary Sensitivity

VirusHB-Chip offers groundbreaking sensitivity in detecting SARS-CoV-2 in plasma, saliva, and stool, transforming COVID-19 diagnostics and treatment strategies.

30 Jan 2025

New Insights into the Structure and Function of a Key Viral Protein

Researchers at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a crucial part of the Nipah virus, a deadly bat-borne infection that has been responsible for human outbreaks every year since its discovery in 1999.

21 Jan 2025

Understanding RapA's Function in E. coli R-loop Control

From a genetic perspective, it is the worst-case scenario for a bacterium: during transcription, freshly created RNA adheres to its DNA template to form a three-stranded structure called an R-loop.

15 Jan 2025

Arabidopsis Study Finds that Centromeres Call the Shots in Retrotransposon Integration

Centromeres play a crucial role in cell division, with CENH3 guiding retrotransposon Tal1 integration, revealing insights into genome evolution and stability.

10 Jan 2025

A revolutionary antibody approach to fight cancer by restoring cellular fitness

Ovarian cancer cells exploit cell competition by altering Flower protein isoforms in stromal cells, promoting tumor survival and potential therapeutic targets.

18 Dec 2024

A breakthrough in muscle cell regeneration and alignment with ultrasonic vibrations.

This study explores the use of ultrasonication to align and enhance the differentiation of myotubes, providing a non-invasive, scalable approach for tissue engineering and regenerative medicine.

13 Dec 2024

Genetic engineering study explored new strategies to combat heat stress in potato crops

This study highlights the impact of the AP3 pathway in potatoes, showing enhanced tuber yield and photosynthetic performance under heat stress, with potential applications for mitigating climate change impacts on crop production.

12 Dec 2024

Single Mutation Could Make H5N1 Bird Flu More Dangerous to Humans

Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one change can increase the risk of becoming a pandemic virus?

6 Dec 2024

The Role of RNA Polymerase and Ribosomes in Gene Expression

DNA within a cell contains the genetic instructions necessary for building proteins.

29 Nov 2024

Advanced Sequencing Uncovers Cause of Rare Mitochondrial Encephalopathy

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 births.

19 Nov 2024

Plastics in Wastewater Found to Harbor Foodborne Pathogens

The study identifies pathogens in plastispheres from WWTPs, underscoring the environmental risks of microplastics and the need for better management strategies.

18 Nov 2024

Caterpillar Fungus Compound Blocks Cancer Growth Signals Within 30 Minutes

Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for cell proliferation and survival.

15 Nov 2024

The Dangers of Zoonotic Diseases

According to a recent study published in Nature, mice and ferrets infected in a high-containment laboratory setting died from a highly pathogenic avian influenza (HPAI) H5N1 virus that was isolated from the eye of a farm worker who contracted the virus from contact with dairy cows.

29 Oct 2024