Protein Synthesis News and Research

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Addressing Protein Leakage in Cells to Improve the Accuracy of Single-Cell Proteomic Data

A new study in Nature Communications presents a solution to protein leakage in single-cell proteomics, improving data quality by identifying and excluding permeabilized cells using a machine learning classifier.

19 May 2025

Novel Compound Targets Salmonella's Infection Mechanism

Pathogenic Salmonella strains inject effector proteins into gastrointestinal tract cells, allowing them to infiltrate and grow. Bacteria are often consumed with contaminated food.

15 Apr 2025

Meet Lariocidin: A Game-Changing Antibiotic That Outsmarts Resistance

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant bacterial infections effectively.

4 Apr 2025

Researchers Unearth Powerful New Antibiotic from Soil

Researchers at McMaster have made a significant discovery that may be the answer to combating antimicrobial resistance, nearly thirty years after the last time a novel class of antibiotics was brought to market.

28 Mar 2025

SRS Microscopy Unlocks New Insights into Cellular Metabolism and Disease

Cellular metabolism plays a critical role in various physiological and pathological processes. High resolution imaging of intracellular metabolic activities is crucial for understanding many biological pathways, and for facilitating disease prognosis and treatment assessment.

14 Mar 2025

Targeting NMDA Receptor Subunit Shows Promise for Fragile X Syndrome

Building on more than two decades of research, a study by MIT neuroscientists at The Picower Institute for Learning and Memory reports a new way to treat pathology and symptoms of fragile X syndrome, the most common genetically-caused autism spectrum disorder.

21 Feb 2025

Breakthrough mRNA Technology Paves the Way for Precision Medicine

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

20 Feb 2025

New Study Uncovers Evolutionary Link in B6 Metabolism

An investigation conducted by a group of scientists at the University of Kentucky’s Martin-Gatton College of Agriculture, Food and Environment has uncovered an unexpected biochemical link between the immune responses of plants and the neurological health of humans.

18 Feb 2025

Researchers Discover New Role of Mitofusin 2 in Cellular Health

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading cause in the currently incurable neurological disease Charcot-Marie-Tooth (CMT).

17 Feb 2025

Synthetic Condensates Turbocharge Protein Production in Bacteria

Biomedical engineers at Duke University have developed a novel synthetic method that enhances bacteria's ability to produce higher quantities of specific proteins, including those that would typically harm them, such as antibiotics.

12 Feb 2025

New Study Reveals Energy-Saving Strategies in Neuronal Protein Synthesis

Nerve cells use incredible energy-saving techniques while still carrying out their primary functions.

10 Feb 2025

Microscopy Technique Tracks Ribosome Activity

A novel microscopy method has been created by researchers from the Tanenbaum group at the Hubrecht Institute to view the activity of ribosomes in cells.

3 Feb 2025

Compound from Sea Sponge Could be Used as a Chemical Probe for Research

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects.

15 Jan 2025

Researchers Discover Genetic Markers for PFAS-Induced Neurotoxicity

Per- and polyfluorinated alkyl substances (PFAS) earn their "forever chemical" moniker by persisting in water, soil and even the human brain.

7 Jan 2025

Novel Approach to Monitor ER-Related Protein Quality Control

Protein synthesis in eukaryotic cells found in plants, animals, and fungi involves more than just the straightforward ribosome assembly of amino acids.

9 Dec 2024

Unraveling the Mystery of Bacterial Protein Synthesis

The process by which cells make protein molecules, which are necessary for life and growth, is known as protein biosynthesis, and it is a very complicated and tightly controlled process.

5 Dec 2024

From Yeast to Humans: Decoding the Link Between Nucleolar Size and Aging

Research reveals that nucleolar enlargement in yeast disrupts genomic integrity, linking size to lifespan and offering insights into aging mechanisms.

5 Dec 2024

The Role of RNA Polymerase and Ribosomes in Gene Expression

DNA within a cell contains the genetic instructions necessary for building proteins.

29 Nov 2024

Unveiling the Hidden Potential of SnoRNAs

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health.

25 Nov 2024