Psychiatry News and Research

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Psychiatry is the treatment, study and prevention of mental disorders.

Same Gene Mutations Can Require Different Treatments in Autism and Schizophrenia

For patients with disorders such as autism and schizophrenia, mutations in the same gene could require different treatments, according to new research from Yale School of Medicine (YSM).

6 May 2025

New Gene Editing Tool Alters Mitochondrial Mutation Levels in Stem Cells

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.

5 May 2025

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Dr. Jeremy Poschmann discusses data-driven approaches in genomics, revealing how immune profiling can predict disease risk and improve patient outcomes.

1 May 2025

New Genetic Insights From Long Read Sequencing in a Teen With Complex Psychiatric Conditions

In a manuscript published today in the American Journal of Psychiatry titled Long-Read Genome Sequencing in Clinical Psychiatry: RFX3 Haploinsufficiency in a Hospitalized Adolescent With Autism, Intellectual Disability, and Behavioral Decompensation, authors describe how they leveraged long-read genomic sequencing (LRS) to make a genetic diagnosis in a17-year-old male with autism spectrum disorder, intellectual disability, and acute behavioral decompensation that would not have been possible by standard methods.

12 Apr 2025

MitoBrainMap Unlocks Secrets of Brain Energy Distribution

Everything the brain does-from storing memories to interpreting sights to regulating emotions-requires energy, all produced by cellular organelles called mitochondria.

28 Mar 2025

Novel Synthetic Antibiotics Against Drug-Resistant Pathogens

Frogs have flourished for hundreds of millions of years, occupying nearly every habitat on Earth, from tropical rainforests to subarctic woodlands.

26 Mar 2025

UCL Study Reveals How Our Brains Simplify Social Interactions

Our brains use basic 'building blocks' of information to keep track of how people interact, enabling us to navigate complex social interactions, finds a new study led by University College London (UCL) researchers.

14 Mar 2025

Study Clarifies Genetic Thresholds for Diagnosing SCA6

The Department of Neurology at Niigata University and National Center of Neurology and Psychiatry has identified pathogenic thresholds for the CAG repeat units (RU) of the CACNA1A gene that causes SCA6.

3 Mar 2025

Mismatch Repair Genes Found to be Key Drivers of Huntington's Disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

12 Feb 2025

New Research Identifies Brain Cells Linked to Alcohol-Induced Insomnia

Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia.

8 Feb 2025

Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

17 Jan 2025

Neuropilin2 Gene Disruption Impacts Brain Circuitry in Autism and Epilepsy

The gene neuropilin2 encodes a receptor involved in cell-cell interactions in the brain and plays a key role in regulating the development of neural circuits.

10 Jan 2025

New Insights into How Early Life Experiences Influence Genetic Expression and Brain Health

In a comprehensive Genomic Press Interview, renowned neuroscientist Dr. Michael Meaney reveals pivotal discoveries about the intricate relationship between genes and environment in shaping brain health.

2 Jan 2025

Bumetanide Treatment Alters Early and Late Social Behaviors in Fragile X Mice

In a comprehensive Genomic Press Interview, researchers from the University of Texas Health Science Center at San Antonio and Hirosaki University have uncovered critical new insights into the developmental trajectory of social behaviors in fragile X syndrome, the leading genetic cause of autism spectrum disorder.

30 Dec 2024

Dopamine and Serotonin Act as Opposing Forces in Learning and Reward

If you've heard of two of the brain's chemical neurotransmitters, it's probably dopamine and serotonin. Never mind that glutamate and GABA do most of the work -; it's the thrill of dopamine as the "pleasure chemical" and serotonin as tender mood-stabilizer that attract all the headlines.

26 Nov 2024

Rutgers Researchers Uncover How Brain Cells Form Functional Networks

Rutgers researchers at the Brain Health Institute (BHI) and Center for Advanced Human Brain Imaging Research (CAHBIR) have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain – interconnected systems that support everything from sensory processing to complex decision-making – paving the way for new insights into brain health and disease.

23 Nov 2024