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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Gene expression changes help understand the mechanism behind noise-induced hearing loss

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.

30 Sep 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, shows study

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021

Tumor suppressor protein binding to RNA also binds DNA, says study

Scientists from the Medical University of South Carolina earlier displayed how hnRNP E1 attaches to metastatic-linked RNAs to prevent their translation.

27 Sep 2021

Scientists analyze the molecular machinery of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Researchers develop a DNA sensor to target and detect infectious viruses in minutes

A new sensor can detect not only whether a virus is present, but whether it's infectious – an important distinction for containing viral spread.

23 Sep 2021

Potential biomarkers help diagnose progressive stages of liver disease

Results of national research pinpointed potential biomarkers that could ultimately be employed for the diagnosis of progressive stages of liver disease.

23 Sep 2021

Researchers provide novel treatment target for common skin condition

Recent research indicates that a familiar inflammatory skin condition might arise due to inadequately regulated sex hormones.

23 Sep 2021

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.

22 Sep 2021

Study unravels novel therapeutic option for the treatment of psoriasis

A group of clinical experts and international scientists have revealed a novel cell type in human skin that contributes to inflammatory skin diseases like psoriasis (PSO) and atopic dermatitis (AD).

17 Sep 2021

UC Riverside scientists aim to turn edible plants into mRNA vaccine factories

The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.

17 Sep 2021

Researchers capture the assembly of ribosomes within human cells

Ribosomes are the multi-component molecular machines that create complex proteins by binding building blocks together as per instructions encoded in the messenger RNAs of the cell.

16 Sep 2021

Researchers infer chemical steps involved in methylthiolation of tRNAs

Recent research revealed the chemical steps in a vital cellular modification mechanism that inserts a chemical tag to certain RNAs. Interference of this process in humans can result in cancers, diabetes, and neuronal diseases.

From Penn State University 16 Sep 2021

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them.

16 Sep 2021

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Neil Hayes, MD, MPH, director of the Center for Cancer Research at the University of Tennessee Health Science Center, is one of two principal investigators for a $1.8 million grant that extends the work of The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

16 Sep 2021

Aptamers for Targeting SARS-CoV-2 Proteins

AMSBIO has further expanded its product range to help in the fight against COVID-19 with the introduction of a new range of aptamers targeting SARS-CoV-2 proteins to aid development of new kits and assays.

From AMS Biotechnology 15 Sep 2021

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

14 Sep 2021

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Researchers have discovered an exclusive mechanism through which two transcription factors stabilize each other’s binding to DNA in fission yeast.

14 Sep 2021

Study could help choose the ideal DNA extraction method for microbiome research

Let's face it, we are a results-driven society. Too focused on the outcome, people don't often think about the "how." For instance, did you think about "how" you got to work this morning or did you just get there? In microbiome studies the results are the graphs and the data but the "how," like commuting, is often just part of a routine.

13 Sep 2021

Viruses buried in marsupials' DNA may help protect against future infections

Fossils of ancient viruses are preserved in the genomes of all animals, including humans, and have long been regarded as junk DNA. But are they truly junk, or do they actually serve a useful purpose?

From The University of New South Wales (UNSW) 9 Sep 2021

Study unearths previously unknown role of CTCF, the transcription regulator

Researchers discovered evidence that CTCF governs chromatin accessibility, the mechanism of opening tightly spooled DNA facilitating gene expression.

9 Sep 2021

RNA News and Research

Gene expression changes help understand the mechanism behind noise-induced hearing loss

Supercoiling and looping can transmit mechanical stress along the DNA backbone, shows study

Tumor suppressor protein binding to RNA also binds DNA, says study

Scientists analyze the molecular machinery of poxviruses at an atomic level

Researchers develop a DNA sensor to target and detect infectious viruses in minutes

Potential biomarkers help diagnose progressive stages of liver disease

Researchers provide novel treatment target for common skin condition

Genetic and epigenetic origin of pediatric liver cancer uncovered

Study unravels novel therapeutic option for the treatment of psoriasis

UC Riverside scientists aim to turn edible plants into mRNA vaccine factories

Researchers capture the assembly of ribosomes within human cells

Researchers infer chemical steps involved in methylthiolation of tRNAs

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Aptamers for Targeting SARS-CoV-2 Proteins

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Study could help choose the ideal DNA extraction method for microbiome research

Viruses buried in marsupials' DNA may help protect against future infections

Study unearths previously unknown role of CTCF, the transcription regulator

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