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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Protein's 'silent code' influences cell movement

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% of their amino acid sequence.

8 Jul 2021

Making memories necessitates a lot of DNA breakage

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

7 Jul 2021

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Neurodevelopmental disorders may be caused by a new genetic variation in a single gene

Genetic variations of a neuro-associated gene termed SPTBN1 have been revealed to cause a neurodevelopmental disorder, according to researchers.

5 Jul 2021

New machine learning method predicts how genes in particular cells are controlled

Researchers from the University of Illinois Chicago have created software that can aid researchers in identifying gene regulators faster.

2 Jul 2021

New 3Cs multiplex approach enables the study of the effect of genetic changes

Dr Manual Kaulich’s team at Goethe University has developed a new 3Cs multiplex approach that permits the effect of genetic alterations in any two genes to be investigated simultaneously in cell cultures.

25 Jun 2021

New methodology assesses whole-genome sequencing data of SARS-CoV-2 mutations

According to researchers from Harvard T.H. Chan School of Public Health and MIT, the use of genome-wide association studies (GWAS) methodology to assess whole-genome sequencing data of SARS-CoV-2 mutations and COVID-19 mortality data can help identify highly pathogenic variants of the virus that should be flagged for containment.

25 Jun 2021

Researchers create first plant embryo gene expression atlas at the single-cell level

A team of researchers from the GMI has created the first plant embryo gene expression atlas at the single-cell level.

22 Jun 2021

Study reveals how cells “read” synthetic ingredients added to a genetic code

If the genome is considered the recipe for life, then base pairs represent the individual ingredients. DNA is made up of these chemical structures, and every living thing on the planet has just four of them.

21 Jun 2021

Genetically engineering NK cells can target and kill glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

18 Jun 2021

'Enabler cells' in tumors could promote cancer metastasis

Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists.

17 Jun 2021

Researchers systematically analyze alternative splicing in the family of glutamate receptors

Alternative splicing can lead to the formation of numerous protein variants. For the first time, alternative splicing has now been systematically analysed for the family of glutamate receptors.

17 Jun 2021

Molecular breeding can enhance the quality of olives

Olives, well-known for their characteristic bitter taste, are in high demand owing to the popularity of the oil that's derived from them.

17 Jun 2021

Newly identified protein regulates the flow of materials in the Drosophila ovary

According to a research work performed by Northwestern Medicine and published in the Current Biology journal, a protein helps guide the flow of materials in the ovary of Drosophila fruit flies during the formation of egg cells.

17 Jun 2021

New method reveals high-resolution structure of biomolecules

A new study integrates molecular dynamics simulations and experimental data to inspect biomolecules in their natural environment.

16 Jun 2021

Human cells can convert RNA sequences into DNA

Cells include machinery that replicates DNA into a new set, and this, in turn, develops into a newly formed cell.

15 Jun 2021

Study sheds new light on the early stages of viral evolution

Scientists from the Universities of York and Leeds, in association with Hilvert Laboratory at the ETH Zurich, have investigated the evolution, structure, and assembly of virus-like particles. According to the researchers, this breakthrough discovery will impact the way viruses are treated in the future.

11 Jun 2021

New “phase separation” protects against premature aging, neurological disorders

According to a new study, a mechanism through which an RNA, called NORAD, drives the Pumilio protein to create liquid droplets in cells—similar to oil in water—appears to closely control the activity of this protein.

11 Jun 2021

Scientists discover two drugs that provide effective SARS-CoV-2 suppression

COVID-19 continues to claim lives across the world and is infecting millions more. Although several vaccines have recently become available, making significant strides towards preventing COVID-19, what about the treatment of those who already have the infection?

From Tokyo University of Science 4 Jun 2021

Scientists develop new method that enables single-cell RNA sequencing in large number of cells

RNA sequencing is a powerful technology for studying cells and diseases. In particular, single-cell RNA sequencing helps uncover the heterogeneity and diversity of our body.

2 Jun 2021

RNA News and Research

Protein's 'silent code' influences cell movement

Making memories necessitates a lot of DNA breakage

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Neurodevelopmental disorders may be caused by a new genetic variation in a single gene

New machine learning method predicts how genes in particular cells are controlled

New 3Cs multiplex approach enables the study of the effect of genetic changes

New methodology assesses whole-genome sequencing data of SARS-CoV-2 mutations

Researchers create first plant embryo gene expression atlas at the single-cell level

Study reveals how cells “read” synthetic ingredients added to a genetic code

Genetically engineering NK cells can target and kill glioblastoma stem cells

'Enabler cells' in tumors could promote cancer metastasis

Researchers systematically analyze alternative splicing in the family of glutamate receptors

Molecular breeding can enhance the quality of olives

Newly identified protein regulates the flow of materials in the Drosophila ovary

New method reveals high-resolution structure of biomolecules

Human cells can convert RNA sequences into DNA

Study sheds new light on the early stages of viral evolution

New “phase separation” protects against premature aging, neurological disorders

Scientists discover two drugs that provide effective SARS-CoV-2 suppression

Scientists develop new method that enables single-cell RNA sequencing in large number of cells

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