Rheumatoid arthritis (RA) is a chronic disease of the joints that can cause a disabling degree of pain and significantly interfere with an individual’s day-to-day living.
A new study from the USC Michelson Center for Convergent Bioscience’s Bridge Institute, in partnership with multinational teams from India, Australia, and Switzerland, sheds insight on these proteins.
Throughout a person’s life, many stimuli can turn on and off many of the genes, resulting in the variances that distinguish people.
Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis.
While the exterior features of a woman can alter throughout pregnancy, scientists are surprisingly ignorant about the interior biological changes that take place.
Conditions like ulcerative colitis and Crohn's disease, which cause inflammation in the body, can be identified or tracked by measuring a protein called calprotectin.
Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life.
The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.
Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).
People afflicted with autoimmune diseases may someday receive help through treatments now under development by a Lawrence Livermore National Laboratory (LLNL) licensee and its' collaborations with two major pharmaceutical companies.
Among the most promising areas of scientific inquiry is the study of the human microbiome and its effect on health. To fuel more rapid progress in this field, Andrea and Donald Goodman and Renee and Meyer Luskin have made a $20 million gift to establish the UCLA Goodman–Luskin Microbiome Center.
Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.
Institut Pasteur, Université Paris Cité, the CNRS, and the Collège de France researchers have employed paleogenomics to trace 10,000 years of human immune system evolution. They examined the genomes of over 2,800 individuals who lived in Europe over the past 10 millennia.
A recent study guided by the Instituto Gulbenkian de Ciência (IGC) shows how anticancer drugs reduce inflammation, establishing them as prospective sepsis treatments.
Trinity researchers have made a significant advance in understanding how inflammation is controlled. They recently discovered that a crucial immunological alarm protein that was previously thought to quiet the immune response apparently performs the opposite.
Four genetic mutations have been linked to progressive multifocal leukoencephalopathy (PML), a rare but sometimes fatal brain infection that can be provoked by dozens of FDA-approved drugs.
The method correctly categorizes macrophage states, which is crucial since these cells can alter their behavior and function as either pro- or anti-inflammatory agents during an immune response.
There is still a large unmet medical need for the treatment of ulcerative colitis, despite recent improvements in the understanding of the pathogenic mechanisms of ulcerative colitis.
Many people with dietary allergies may have minor symptoms when they consume foods that trigger them, but for some, the consequences could be lethal. In lab experiments, a bacterial chemical called butyrate produced by healthy microbiomes has shown promise in preventing allergy reactions, but it is unpleasant to consume.
Mitochondria are self-contained organelles that reside inside cells and are tasked with producing the chemical energy required to power vital tasks necessary for life and wellbeing. They have their own mini-chromosome and DNA.
According to a recent study of information from the Veterans Affairs Million Veteran Program, there are genetic correlations between COVID-19 severity and specific medical disorders that are established risk factors for severe COVID-19.