Ribosome News and Research

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Human rRNA genes differed based on a person’s geographic ancestry

Genome research that explored gene variants that are considered a crucial building block for protein-synthesizing microscopic structures took an unexpected turn.

4 Feb 2022

Stanford study reveals how ribosomes may contribute to age-related diseases

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein folding.

20 Jan 2022

Viral RNA undergoes conformational changes to hijack host cells, says study

Scientists from the University of Colorado Anschutz Medical Campus recently identified how an RNA molecule from a virus develops a complex, three-dimensional structure, and is capable of changing its shape to hijack host proteins.

25 Nov 2021

Researchers develop new approach to selectively turn on gene therapies in target cells

Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection then triggers production of a specific protein from a transgene, or artificial gene.

From Massachusetts Institute of Technology (MIT) 29 Oct 2021

New eToeholds could make RNA therapeutics more safer and effective

RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.

29 Oct 2021

Novel platform enables sequence-unconstrained traceless protein synthesis

According to recent research published a multi-enzyme platform was created for sequence-unconstrained traceless protein synthesis and modification.

26 Oct 2021

Researchers capture the assembly of ribosomes within human cells

Ribosomes are the multi-component molecular machines that create complex proteins by binding building blocks together as per instructions encoded in the messenger RNAs of the cell.

16 Sep 2021

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

CMT, a rare hereditary condition, commences when genetic changes interrupt the transmission of nerve signals from the brain to the muscles of the extremities, specifically those of the lower limbs.

16 Sep 2021

Researchers reveal why nerve cell’s protein production slows down in CMT patients

A team led by MDC researcher Marina Chekulaeva has figured out why protein production slows down in the nerve cells of people suffering from Charcot-Marie-Tooth disease. This discovery could lead to a new therapeutic approach, the scientists report in the journal "Nucleic Acids Research".

16 Sep 2021

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Researchers have discovered an exclusive mechanism through which two transcription factors stabilize each other’s binding to DNA in fission yeast.

14 Sep 2021

Experts decode the genetic mechanism governing the speed of mRNA translation

The genetic material of all eukaryotic organisms is stored in the cell nucleus in the form of DNA. The DNA is first transcribed into messenger RNA in the cell cytoplasm and later translated into protein using ribosomes for it to be used, where ribosomes are small machines capable of decoding messenger RNA to synthesize the relevant proteins.

1 Sep 2021

Study analyzes the role of eIF4A3 protein in cancer cell growth

Cell growth requires new proteins and the same applies to cancer cells. Scientists analyzed the protein eIF4A3 and its role in the growth of cancer cells.

10 Aug 2021

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Antibiotics used to treat common bacterial infections may potentially be used to treat human illnesses such as cancer, at least theoretically.

27 May 2021

Study shows that autophagy plays a key role in messenger RNA degradation

Autophagy is essential in messenger RNA (mRNA) degradation, according to researchers from the Tokyo Institute of Technology (Tokyo Tech).

27 Apr 2021

Study highlights the importance of autophagy in gene regulation

A fine balance between the production and degradation of biomolecules is required for optimal cell function. Autophagy is a mechanism through which cells break down and recycle their own components.

20 Apr 2021

Study reveals RNA regulatory mechanisms within transcription-translation couplings

To gain a better understanding of how bacterial RNA gives rise to proteins scientists are now focusing on the special way this process takes place in bacteria.

15 Apr 2021

Mutant protein plays key role in Huntington’s disease

Back in 1993, researchers had discovered that Huntington’s disease is typically caused by a single mutated gene, known as HTT.

8 Mar 2021

Scientists gain new insights into ribosome formation to identify potential drug targets

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process.

2 Mar 2021

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

23 Feb 2021

Scientists discover how the 3D structure of eye-lens proteins is formed

The lens of the human eye gets its transparency and refractive power from the fact that certain proteins are densely packed in its cells.

11 Feb 2021

Ribosome News and Research

Human rRNA genes differed based on a person’s geographic ancestry

Stanford study reveals how ribosomes may contribute to age-related diseases

Viral RNA undergoes conformational changes to hijack host cells, says study

Researchers develop new approach to selectively turn on gene therapies in target cells

New eToeholds could make RNA therapeutics more safer and effective

Novel platform enables sequence-unconstrained traceless protein synthesis

Researchers capture the assembly of ribosomes within human cells

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

Researchers reveal why nerve cell’s protein production slows down in CMT patients

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Experts decode the genetic mechanism governing the speed of mRNA translation

Study analyzes the role of eIF4A3 protein in cancer cell growth

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Study shows that autophagy plays a key role in messenger RNA degradation

Study highlights the importance of autophagy in gene regulation

Study reveals RNA regulatory mechanisms within transcription-translation couplings

Mutant protein plays key role in Huntington’s disease

Scientists gain new insights into ribosome formation to identify potential drug targets

Study reveals specialized mechanism for translation of mitochondrial genome into proteins

Scientists discover how the 3D structure of eye-lens proteins is formed

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