Sclerosis News and Research

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Avoiding Post-COVID ‘Brain Fog’

Memory loss and difficulties learning are two of the numerous perplexing symptoms in COVID-19 infected patients.

22 Mar 2024

Non-Immune Cells Form Memory, Boosts Inflammatory Response

An essential component of adaptive immunity is immunological memory, which is the capacity to react to a foreign material or antigen more quickly and intensely when exposed again.

21 Mar 2024

Decoding the Dynamics of Multiple Sclerosis Lesions

Scientists in Sweden were able to uncover the molecular mechanisms behind the development of lesions in multiple sclerosis by employing sophisticated techniques. The latest findings are detailed in the journal Cell by a team of researchers from Karolinska Institutet and Stockholm University.

21 Mar 2024

New Biomarker Offers Early Detection of ALS and FTD

Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk show host Wendy Williams), are linked by more than the fact that they both damage nerve cells critical to normal functioning -; the former affecting nerves in the brain and spinal cord leading to loss of movement, the latter eroding the brain regions controlling personality, behavior and language.

19 Mar 2024

Study Reveals Key Role of STAP-1 in Immune Function

A recent study has illuminated the significance of the protein STAP-1 in activating specific immune cells.

13 Mar 2024

NIH Researchers Map Vulnerable Sites on Epstein-Barr Virus gp42 Protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

13 Mar 2024

Study Reveals STAP-1 Protein's Role in Immune Disorders

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

12 Mar 2024

Breaking Down the Complex Mechanisms of Neurodegeneration

By using a novel neuronal cell culture model, researchers at the University of Zurich have illuminated the complex mechanisms behind neurodegeneration.

23 Feb 2024

Overlooked Sequence in Immunology Protein Holds Promise for New Autoimmune Therapies

Our immune system is remarkably powerful. It quickly assembles teams of cells to eliminate threats inside our bodies.

22 Feb 2024

Researchers Unveil New Mechanism of Immune Cell Training in Thymus Gland

Immune cells must learn not to attack the body itself. A team of researchers from the Technical University of Munich (TUM) and the Ludwig Maximilian University of Munich (LMU) has discovered a previously unknown mechanism behind this: other immune cells, the B cells, contribute to the "training" of the T cells in the thymus gland.

22 Feb 2024

Uncovering How to Protect Nerves in Neurodegenerative Diseases

Researchers at the Case Western Reserve University School of Medicine have led a team that has discovered a novel therapeutic strategy for treating neurodegenerative illnesses, raising the prospect of better care for conditions like multiple sclerosis, Alzheimer's disease, Parkinson's disease, and Vanishing White Matter disease.

21 Feb 2024

Stem Cell-Derived Brain Organoids on Ax-3 Mission Seek to Improve Modeling for Neurodegenerative Diseases

More than 5 million people worldwide are living with neurodegenerative disorders like Parkinson’s disease and primary progressive multiple sclerosis (PPMS).

19 Jan 2024

EBV-Targeting T-Cells Linked to Early MS Damage

The body's immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multiple sclerosis, according to a new study led by UTHealth Houston.

12 Jan 2024

Ancient DNA Reveals Reason for High Multiple Sclerosis and Alzheimer’s Rates in Europe

Researchers have created the world’s largest ancient human gene bank by analysing the bones and teeth of almost 5,000 humans who lived across western Europe and Asia up to 34,000 years ago.

10 Jan 2024

New Cell Model Paves Way for Faster Treatments for Neuromuscular Diseases

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

20 Dec 2023

From Mice to Men: New Studies Bridge the Gap in Brain Cell Gene Expression Across Species

Despite all our cells sharing the same DNA, there are thousands of different cell types in the human brain, each with a unique structure and function.

14 Dec 2023

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

5 Dec 2023

Research Offers a Promising Avenue for Improving T-Cell-Based Cancer Therapies

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

4 Oct 2023

Study Delves Deeper into Understanding How Humans Behave

Throughout a person’s life, many stimuli can turn on and off many of the genes, resulting in the variances that distinguish people.

20 Sep 2023

How Scientists are Using iPSCs to Develop New Therapies

In 1998, scientists reported being able to derive cells from human embryos that could develop into almost any cell in the body. In 2007, the field took a huge leap when scientists discovered they could reprogram human adult skin cells to act like these embryonic stem cells.

20 Sep 2023