Signaling Pathway News and Research

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New gene helps drive the development of the common lung cancer type

At the NYU Langone Health’s Perlmutter Cancer Center, a team headed by scientists has determined a gene that forces the development of the second most common type of lung carcinoma.

From New York University (NYU) 11 Jan 2023

Deubiquitinating enzymes vital for endosomal transport identified

The University of Konstanz’s Plant Physiology and Biochemistry research group has discovered previously unrecognized molecular mechanisms by which plants acclimatize to their environment—vital basic knowledge in times of climate change.

28 Nov 2022

The critical role of amino acid sensing pathways in driving colorectal cancer

A dietary modification may be essential to improving colon cancer treatment, according to research from the University of Michigan Rogel Cancer Center.

22 Nov 2022

Mitochondria play a crucial role in the regulation of the NF-κB signaling pathway

Mitochondria are highly regarded as the cell's powerhouse. However, these cellular organelles are essential for more than only energy production: Professor Konstanze Winklhofer and her colleagues at Ruhr University Bochum’s Faculty of Medicine have found that mitochondria play an essential role in signal transduction in innate immune pathways.

21 Nov 2022

Low protein synthesis in humans causes rare intestinal disease

According to a recent study, which will be published on November 1st, 2022, by Yun-Fei Li of Zhejiang University School of Medicine in Hangzhou, China, and colleagues, a decrease in protein synthesis in growing gut cells contributes to a rare genetic condition, and an affordable nutritional supplement could help reverse that decrease.

3 Nov 2022

Scientists uncover the robust mechanism used by insects

Researchers at IRB Barcelona, under the direction of Dr Marco Milan, have identified a very robust system that insects use for wing formation and regeneration.

25 Aug 2022

Biotrophic fungus uses host auxin signaling pathway for its own purposes

Ustilago maydis attacks and reproduces in the aerial parts of the corn plant. At the location of the infection, massive tumor-like tissue growths frequently develop. The size of these galls can exceed that of a child’s skull.

12 Aug 2022

Researchers find active protein in tumor cells might help in new cancer treatments

A discovery regarding how a particular protein is triggered in tumor cells, conducted by researchers at the University of California, Irvine, may lead to more effective therapies for some of the deadliest types of cancer.

20 Jul 2022

Research highlights how natural cellular molecules trigger plant immune responses

Natural cellular molecules that control vital plant immune responses have been found, according to two studies conducted by scientists at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, and their Chinese counterparts.

From The Max Planck Institute 11 Jul 2022

Scientists link the function of specific domain of proteins to a cancer trigger in humans

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

6 Jul 2022

New biomedical research tool may help advance molecular diagnostics and drug discovery

A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery.

30 Jun 2022

Researchers discover effective therapy for pediatric T-acute leukemia

The most frequent type of malignancy in kids is acute lymphoblastic leukemia (ALL).

27 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Researchers discover protein that enhances muscle mass

Humans are not just pumping iron in the gym, or not just oxygenating muscle cells, which keeps those muscles healthy, powerful, and developing—a process known as hypertrophy—that is defined as an increase in muscle mass, caused by an increase in muscle cell size.

29 Apr 2022

Researchers analyze leaf angle genetics for improved crop yields

Plants have long been the main source of nutrition. The demand for food production is always increasing as the human population grows exponentially. Since agricultural land is constrained, meeting this rising need will necessitate developing new ways to increase the productivity of existing crops.

29 Apr 2022

Signaling Pathway News and Research

New gene helps drive the development of the common lung cancer type

Deubiquitinating enzymes vital for endosomal transport identified

The critical role of amino acid sensing pathways in driving colorectal cancer

Mitochondria play a crucial role in the regulation of the NF-κB signaling pathway

Low protein synthesis in humans causes rare intestinal disease

Scientists uncover the robust mechanism used by insects

Biotrophic fungus uses host auxin signaling pathway for its own purposes

Researchers find active protein in tumor cells might help in new cancer treatments

Research highlights how natural cellular molecules trigger plant immune responses

Scientists link the function of specific domain of proteins to a cancer trigger in humans

New biomedical research tool may help advance molecular diagnostics and drug discovery

Researchers discover effective therapy for pediatric T-acute leukemia

Researchers discover a new interferon-gamma receptor signaling pathway

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Researchers discover protein that enhances muscle mass

Researchers analyze leaf angle genetics for improved crop yields

Bone growth protein may help treat newborns with rare genetic lung condition

Stem cell-mediated gene therapy technique helps to boost bone regeneration

Critical signaling pathways in immune cells could reduce Alzheimer’s progression

Study shows how T cell-derived interleukin-22 promotes antibacterial defense of colonic crypts

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