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Infant's immune system may be better than the adult immune system

As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

New technology can help detect the activity of CRISPR gene editing tools

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy's Oak Ridge National Laboratory.

13 Dec 2021

Researchers regenerate cartilage using novel protein fragment

The existing methods for the regeneration of injured cartilage generate tissue that breaks down. This deterioration eventually leads to osteoarthritis—the commonly seen form of arthritis—affecting over 32.5 million grown-ups in the United States, as per the Centers for Disease Control and Prevention.

13 Dec 2021

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

Research team grows mini-stomach across varying stages of development

A group of researchers led from Great Ormond Street Hospital (GOSH) hinged on recent progress to culture “mini-organs” in a lab, called organoids.

From University College London 7 Dec 2021

Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

A novel therapeutic approach inhibits the growth of metastatic tumors in mice by coercing cancer cells into a dormant state—where they cannot proliferate.

25 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Simultaneously Measuring 7,000 Proteins: Groundbreaking Proteomics from SomaLogic

In this interview, we speak to Roy Smythe, CEO of SomaLogic, about their groundbreaking proteomics technology that can simultaneously measure 7,000 proteins.

From SomaLogic 4 Nov 2021

OHSU part of new project investigating stem cell therapy as potential glaucoma treatment

Oregon Health & Science University is part of a national research project investigating stem cell therapy as a potential treatment for glaucoma, the world's second leading cause of blindness.

1 Nov 2021

SARS-CoV-2 virus may be able to infect the inner ear, study shows

Many Covid-19 patients have reported symptoms affecting the ears, including hearing loss and tinnitus. Dizziness and balance problems can also occur, suggesting that the SARS-CoV-2 virus may be able to infect the inner ear.

1 Nov 2021

Study identifies genes involved in people with osteoarthritis

The major cause of pain and disability globally is osteoarthritis.

1 Nov 2021

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

29 Oct 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Internal workings of next-word prediction models closely fit the human brain

In the past few years, artificial intelligence models of language have become very good at certain tasks. Most notably, they excel at predicting the next word in a string of text; this technology helps search engines and texting apps predict the next word you are going to type.

26 Oct 2021

Targeted drug shows promise against brain metastases from kidney cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

22 Oct 2021

Surgery News and Research

Infant's immune system may be better than the adult immune system

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

New technology can help detect the activity of CRISPR gene editing tools

Researchers regenerate cartilage using novel protein fragment

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

Research team grows mini-stomach across varying stages of development

Novel therapeutic approach forces cancer cells to dormancy, prevents metastasis

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Simultaneously Measuring 7,000 Proteins: Groundbreaking Proteomics from SomaLogic

OHSU part of new project investigating stem cell therapy as potential glaucoma treatment

SARS-CoV-2 virus may be able to infect the inner ear, study shows

Study identifies genes involved in people with osteoarthritis

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Internal workings of next-word prediction models closely fit the human brain

Targeted drug shows promise against brain metastases from kidney cancer

New insights into the role of fat cells in cognitive decline and neurodegeneration

High tumor-infiltrating lymphocytes could indicate a better chance of survival in esophageal cancer

Type A immunoglobulins play a key role in keeping the intestinal flora in balance

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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