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Personal genome sequencing and personalized medicine

Genetic mutations have given life on Earth a stunning variety of various sizes, colors, and shapes. Some changes are beneficial, while others are dangerous or ineffective. There are about 4.5 million genetic variants per individual.

31 Mar 2023

Previously unknown telomere and cancer connection to the immune system revealed

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

31 Mar 2023

Study reports a new target to fight against antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

30 Mar 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

24 Mar 2023

New type of neural implant could restore limb function to amputees

Researchers have developed a new type of neural implant that could restore limb function to amputees and others who have lost the use of their arms or legs.

23 Mar 2023

Curcumin could enhance ovarian cancer treatments

A pharmacology researcher at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) has co-authored a new study that makes a strong case for why a golden spice commonly found in curry could enhance ovarian cancer treatments.

23 Mar 2023

Key Hox genes control stem cells involved in bone formation and repair

A new study discovered that genes that have long been known to regulate bone formation before birth also govern bone healing later in life.

From New York University (NYU) 21 Mar 2023

Keeping lymph nodes in the body can boost the efficacy of cancer immunotherapy

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

21 Mar 2023

Neoadjuvant dual immunotherapy and chemotherapy improve outcomes in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

20 Mar 2023

Aston University receives funding for the development of a diagnostic tool for children with brain tumors

Birmingham based charity, Help Harry Help Others and Aston University researchers, are working together to develop a pioneering pre-surgical diagnostic tool, which could see the eventual outcome of children with brain tumors drastically improve.

15 Mar 2023

Study identifies previously unknown cell types that drive the onset of osteoarthritis

A Michigan Medicine study has identified a new potential target for treating osteoarthritis – a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.

10 Mar 2023

Study shows mothers provide necessary microbes to babies born via cesarean

Can newborns delivered by cesarean surgery lack vital microbes? Recent data suggests that “no” could be the answer. Mothers are able to transmit bacteria to their babies through alternative, compensating channels, according to research published in the journal Cell Host & Microbe on March 8th, 2023.

10 Mar 2023

Revolutionary drug blocks a gene associated with driving the spread of bone cancer

Researchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer.

8 Mar 2023

Study pinpoints a key cause of metastasis from an aggressive form of pediatric brain cancer

New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.

7 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Gaining insights into the muscle damage protective effect

Loss of muscle strength can be one of the most damaging outcomes when someone is unable to move a part of their body for a long period of time.

2 Mar 2023

Redefining low-risk WNT-pathway medulloblastoma based on newer biological information

A new research perspective was published in Oncotarget's Volume 14 on February 7, 2023, entitled, "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?"

28 Feb 2023

Women over 50 with genetic BRCA1 or BRCA2 mutation face a high risk of cancer

Although genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mutations continue to face a high risk of cancer incidence after age 50, even if they have not been previously diagnosed with cancer.

27 Feb 2023

Genes can be used to better predict the likelihood of kidney cancer recurrence

A decade-long international study into kidney cancer has shown that doctors can predict the likelihood of a patient's disease returning by looking at DNA mutations in their tumors.

24 Feb 2023