Surgery News and Research

RSS

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Liver fibrosis might be treatable with selective immunotoxins

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

13 Jul 2021

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

13 Jul 2021

Universal stem cells exhibit the potential for more cost-effective cell therapy

Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.

8 Jul 2021

Western high-fat diet can increase the risk of painful conditions

A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a groundbreaking paper authored by a team led by The University of Texas Health Science Center at San Antonio, also referred to as UT Health San Antonio.

24 Jun 2021

Genetically engineering NK cells can target and kill glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

18 Jun 2021

New technology offers an alternative way to produce highly detailed images of the brain

The gold standard in functional brain imaging for over two decades, functional magnetic resonance imaging (fMRI) has transformed the landscape of research and clinical care. Yet, because of its cost and functional limitations, scientists have continued to look for new ways to see into the human brain.

15 Jun 2021

World Food Safety Day 2021: An Interview with the World Health Organization (WHO)

AZoLifeSciences interviews Francesco Branca, director of the Department of Nutrition and Food Safety at the World Health Organization, for World Food Safety Day 2021.

From World Health Organization (WHO) 14 Jun 2021

New research focuses on possible treatment options for childhood brain cancer

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.

11 Jun 2021

New insights on how synovial sarcoma develops and spreads

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

7 Jun 2021

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Treatment with an immunotherapy drug following kidney cancer surgery, prolonged disease-free survival rates in patients at high risk for recurrence, according to an interim report of a phase 3 clinical trial of adjuvant immunotherapy in this patient population.

4 Jun 2021

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery. These findings of a large SWOG Cancer Research Network clinical trial, S1404, will be presented at the ASCO annual meeting June 6, 2021.

4 Jun 2021

Neuromorphic chip recognizes complex biosignals, can help monitor epilepsy

Current neural network algorithms produce impressive results that help solve an incredible number of problems.

27 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

Metagenomic sequencing helps examine differences in the gut microbiome after injury

Researchers used metagenomic sequencing to identify variations in virus and bacterial populations that occur following spinal cord injury in mice.

13 May 2021

New method can enable early detection and treatment of cerebral aneurysms

Cerebral aneurysms are malformations caused by abnormalities on the walls of blood vessels in the brain. When these blood vessels rupture, about 30% of the sufferers die on the spot, giving these the rightful label of 'ticking bombs in the head'.

11 May 2021

Lack of functional GAS2 gene causes severe hearing impairment in mice

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

10 May 2021

New technology efficiently detects gene mutation in blood with low error rate

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

5 May 2021

Study reveals genetic mutation associated with exfoliation syndrome

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma.

5 May 2021

Holographic histopathology increases imaging speed, resolution for diagnostics

Histology involves the investigation of biological tissues at the microscopic level. Histology is also known as microscopic anatomy and is commonly used to diagnose cancer and other diseases.

3 May 2021

Surgery News and Research

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Liver fibrosis might be treatable with selective immunotoxins

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Universal stem cells exhibit the potential for more cost-effective cell therapy

Western high-fat diet can increase the risk of painful conditions

Genetically engineering NK cells can target and kill glioblastoma stem cells

New technology offers an alternative way to produce highly detailed images of the brain

World Food Safety Day 2021: An Interview with the World Health Organization (WHO)

New research focuses on possible treatment options for childhood brain cancer

New insights on how synovial sarcoma develops and spreads

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Neuromorphic chip recognizes complex biosignals, can help monitor epilepsy

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Metagenomic sequencing helps examine differences in the gut microbiome after injury

New method can enable early detection and treatment of cerebral aneurysms

Lack of functional GAS2 gene causes severe hearing impairment in mice

New technology efficiently detects gene mutation in blood with low error rate

Study reveals genetic mutation associated with exfoliation syndrome

Holographic histopathology increases imaging speed, resolution for diagnostics

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics